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254 results about "Abnormal thyroid" patented technology

Benign and malignant nodule grading evaluation system based on large model fusion ultrasonic imaging and thyroid gene marker

PendingCN120452757AImage analysisHealth-index calculationMalignancyGold standard (test)
The invention discloses a benign and malignant nodule grading evaluation system based on large model fusion ultrasonic imaging and thyroid gene markers, which can organically fuse non-invasive examination and serological detection, can simulate and diagnose multi-grade risk probability information provided by a gold standard, realizes similar risk grading estimation in a non-invasive mode, and has a wide application prospect. The thyroid nodule risk assessment method can provide visual explanation conforming to clinical logic based on comprehensive information of iconography and molecular biology, can significantly improve the accuracy of thyroid nodule risk assessment, can also effectively improve clinical decision-making efficiency and patient credibility, and has important clinical application prospects. The system comprises a data acquisition module, an ultrasonic image feature extraction module, a gene marker feature extraction module, a multi-modal fusion and hierarchical reasoning module and a generation module.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Thyroid ultrasonic robot automatic scanning method, device and equipment based on RGB image and depth information and medium

The invention relates to the technical field of computer vision, and discloses a thyroid ultrasonic robot automatic scanning method, device and equipment based on RGB images and depth information and a medium, and the method comprises the steps: obtaining image information and depth information, coding the depth information, fusing and recognizing a target scanning area, determining an initial scanning point and an initial scanning direction, controlling the scanning probe to scan and collect a real-time scanning image, analyzing the real-time scanning image to recognize a preset target and an artifact area, adjusting a scanning posture and a scanning path based on a recognition result, monitoring a continuous existence state of the preset target, and stopping scanning when the preset target is not recognized continuously. The target area is identified by fusing the multi-modal image information, the scanning posture and path are dynamically adjusted in combination with real-time image analysis, scanning termination is intelligently controlled according to the target detection result, the positioning accuracy, image quality and standardization level of ultrasonic scanning are improved, and the method is suitable for automatic ultrasonic imaging of thyroid and superficial organs.
Owner:SHENZHEN BEAUTIFUL RUBIKS CUBE ROBOT CO LTD

Thyroid intraoperative real-time navigation method and system based on multi-mode optical fusion

The invention discloses a thyroid intraoperative real-time navigation method and a thyroid intraoperative real-time navigation system based on multi-mode optical fusion. The thyroid intraoperative real-time navigation method comprises the following steps: outputting visible light through an endoscope and coupling light waves of a narrow-band multispectral light source to irradiate an operative field, exciting parathyroid glands to generate near-infrared fluorescence, and receiving reflected visible light, split light, near-infrared fluorescence and laser speckle signals through an endoscope probe. And separating the composite optical signal into four channels, and respectively generating an anatomical structure color image, a blood vessel spectroscopic image, a parathyroid gland near-infrared fluorescence image and a laser speckle image. Performing decorrelation processing on the laser speckle image to generate a blood flow dynamic pseudo-color decorrelation speckle image; an anatomical structure, a blood vessel center line, a parathyroid gland contour and blood flow dynamic feature points are extracted through a multi-modal registration technology, after affine transformation space alignment is conducted, a comprehensive imaging map containing the anatomical structure, blood vessel distribution and parathyroid gland function marking information is generated through a wavelet fusion algorithm, and intraoperative multi-dimensional real-time tissue navigation is achieved.
Owner:THE FIFTH AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV

Thyroid tumor diagnosis method and system based on ultrasonic and cytological image conjoint analysis

The invention discloses a thyroid tumor diagnosis method and system based on ultrasonic and cytological image conjoint analysis. The method comprises the following steps: converting a thyroid B ultrasonic image of a patient to be diagnosed into an image feature vector FUS; performing structured feature extraction on the thyroid cytological image of the patient to be diagnosed to obtain a structured feature vector FCYTO; the image feature vector FUS and the structured feature vector FCYTO are converted into a fusion Token sequence; and inputting the Token into a multi-modal feature fusion and prediction network based on a Transform architecture, and carrying out feature fusion and classification prediction so as to obtain the probability that the thyroid tumor of the patient to be diagnosed is malignant. The thyroid tumor diagnosis based on multi-modal fusion is carried out on the basis of ultrasonic and cytological images, so that the diagnosis accuracy is improved.
Owner:金凤实验室

Thyroid nodule ultrasonic image classification method and system based on feature extraction

The invention relates to the technical field of image classification, in particular to a thyroid nodule ultrasonic image classification method and system based on feature extraction, and the method comprises the following steps: based on thyroid nodule ultrasonic image data, calling a pixel normalization function to adjust a gray scale range to a set interval, screening an isolated noise region, and carrying out the smooth filtering, and acquiring the ultrasonic image after smoothing filtering. According to the method, by adjusting the gray scale range and screening isolated noise areas, gray scale distribution is balanced, noise interference is reduced, image readability is improved, edge change is recognized by analyzing the gradient direction through a small-scale convolution kernel, texture features are extracted through a medium-scale filter, redundancy is reduced in combination with pooling operation, and the feature hierarchical expression ability is enhanced; the edge sharpness parameter is calculated, the feature weight is optimized, the edge sharpness and the classification adaptability are improved, the local feature segmentation precision is improved, the classification boundary is adjusted according to the similarity score, the classification loss measurement is optimized, the error offset is reduced, and the classification stability and accuracy are improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Automatic diagnosis method for thyroid pathology image

The invention discloses an automatic diagnosis method of a thyroid pathological image, and belongs to the technical field of medical pathological image auxiliary intelligent diagnosis, and the method comprises the following steps: constructing a thyroid tumor pathological image data set, preprocessing a pathological image, carrying out multi-scale fusion, carrying out feature extraction, carrying out feature fusion, inputting a CLAM-SB multi-instance learning model, and generating a visual heat map. The invention provides a thyroid pathology image automatic diagnosis method based on weak supervision multi-instance learning and multi-scale feature fusion, which can effectively improve the accuracy of pathology tissue region segmentation and pathology image classification, reduce the workload of pathologists and improve the diagnosis efficiency and reliability.
Owner:THE SECOND AFFILIATED HOSPITAL OF GUANGXI UNIV OF SCI & TECH

Thyroid ultrasound image diagnosis method based on deep learning

The invention discloses a thyroid ultrasound image diagnosis method based on deep learning, and the method comprises the following steps: collecting a thyroid ultrasound original image set, and carrying out the preprocessing; performing focus segmentation on the standardized thyroid ultrasound image set; performing morphological constraint and boundary refinement; calculating the blood flow direction, blood flow velocity and blood flow power of each thyroid focus area and neighborhood; generating a preliminary fusion feature map based on a feature adaptive deep learning network, and fusing the preliminary fusion feature map with the thyroid focus blood flow feature vector set; obtaining a thyroid focus detection list through thyroid focus benign and malignant discrimination branches; and generating thyroid focus structured diagnosis data records based on the thyroid focus detection list, and writing the thyroid focus structured diagnosis data records into a computer-aided diagnosis system. According to the method, deep learning and multi-modal blood flow features are fused, intelligent diagnosis of the thyroid focus is achieved, and the method has the advantages of being high in precision, high in interference resistance and structured in result.
Owner:SHANGHAI TENTH PEOPLES HOSPITAL

Thyroid function abnormality detection system based on big data

InactiveCN120356678AMedical data miningMolecular entity identificationReference intervalsThyroid dysfunction
The invention relates to the technical field of health monitoring, in particular to a thyroid dysfunction detection system based on big data, which comprises a hormone data management module, a trend inflection point identification module, a section structure judgment module, a label dynamic updating module and a periodic evolution evaluation module. According to the method, continuous modeling is carried out on hormone concentration dynamic characteristics through multi-time-point data time sequence arrangement in hormone detection records, local extreme points of hormone values are recognized, key fluctuation inflection point positions are defined, an abnormal fluctuation range is recognized, and a reference interval ratio judgment mechanism is introduced to improve the abnormal recognition precision; the dynamic tracking of the function state change process is realized by recording the label evolution trajectory through the continuous state label comparison and updating process, the identification capability of potential function abnormality is enhanced by utilizing the quantitative evaluation of the individual state fluctuation stability, the identification efficiency and the monitoring timeliness of the key intervention individual are improved, and the monitoring accuracy is improved. And the continuity of thyroid function state change identification and the accuracy of intervention target identification are improved.
Owner:SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY (SHANDONG PROVINCIAL HOSPITAL)

Thyroid nodule ultrasound image segmentation method fusing factorization VMama and characteristic frequency band separation

The invention discloses a thyroid nodule ultrasound image segmentation method fusing factorization VMama and characteristic frequency band separation, and relates to the field of computer vision assisted medical treatment. Preprocessing the thyroid nodule ultrasonic image data set; inputting the processed image into an encoder of a segmentation model FMVM-DFFT for processing, extracting image features in a multi-level manner by using an FMVSS module based on VSS, and further finely extracting and fusing feature information under different frequencies by using a feature frequency band separation module DFFT; the method comprises the following steps of: transforming input features into a frequency domain from a space domain by adopting improved fast Fourier transform, decomposing the input features into high and low frequency components, respectively optimizing the high and low frequency components through point-by-point convolution and a channel attention module, recombining the high and low frequency components in a complex domain, and restoring the high and low frequency components to the space domain through inverse Fourier transform; then, through dynamic convolution, layer normalization processing and reserved input features, merging and transmitting to a decoder; the details of the segmentation result are further optimized; the problem that edge segmentation is inaccurate and not fine is solved.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Thyroid image segmentation method and system for obtaining multi-scale feature fusion based on UNet and deformable convolution

The invention discloses a thyroid image segmentation method and system for obtaining multi-scale feature fusion based on UNet and deformable convolution, and belongs to the technical field of medical image processing and computer vision. A model DAmUNet of a deformable convolution and multi-scale attention feature fusion module is introduced into a UNet network architecture, the deformable convolution is adopted in an encoder and a decoder to replace traditional convolution, in the deepest layer of the encoder, the multi-scale attention feature fusion module is adopted, encoding features of the encoder with different resolutions are used as input, and the multi-scale attention feature fusion module is used as input. Channel weighting is carried out on the deepest layer coding features through a double-input channel attention mechanism to generate fusion features; and taking the fusion features as decoder input, and finally obtaining a pixel-level segmentation result of the thyroid region. The method effectively improves the segmentation precision and robustness, is excellent in Dice, IoU and other indexes, and can be widely applied to the scenes of thyroid volume calculation, preoperative evaluation and the like.
Owner:ZHEJIANG CENT FOR DISEASE CONTROL & PREVENTION +1

Thyroid ultrasound signal intelligent analysis and diagnosis method and system

The invention provides a thyroid ultrasonic signal intelligent analysis and diagnosis method and system, and relates to the technical field of ultrasonic signal analysis, and the method comprises the steps: calculating different depth noise distribution, automatically adjusting a filtering parameter value, and carrying out the filtering through anisotropic diffusion; segmenting the processed image to obtain a nodule region; acoustic characteristic data, acoustic characteristic parameter data and image characteristic data are extracted to form a comprehensive characteristic vector, and dimension reduction is carried out; and calculating a feature association weight for optimization to obtain a classification result, and generating a diagnosis report. The thyroid ultrasound image analysis precision is improved, and intelligent diagnosis of benign and malignant nodules is achieved.
Owner:HEBEI XIONGAN HONGZE TECHNOLOGY CO LTD +1

Disease diagnosis method and system based on multi-mode space-frequency domain adaptive fusion

The invention discloses a disease diagnosis method and system based on multi-modal space-frequency domain adaptive fusion, and relates to the field of artificial intelligence and biomedical engineering.The method comprises the steps that multi-modal data are standardized, the unified and standardized multi-modal data are coded, and multi-modal initial feature representation is obtained; after projection and gating alignment and cross-modal interactive attention alignment are carried out on the initial feature representation of each modal, enhanced representations of each modal are obtained, and then the enhanced representations of each modal are fused into a shared feature representation; performing deep feature extraction on the enhanced representation of each mode to obtain deep features of each mode, and performing adaptive multi-domain feature enhancement processing to obtain multi-domain enhanced features of each mode; performing semantic alignment on the multi-domain enhanced features of each mode, and then performing fusion through a hierarchical attention mechanism to obtain fusion features; and the fusion features are input into a diagnosis network for prediction, a disease diagnosis result is obtained, and the intelligent diagnosis precision and robustness of papillary thyroid carcinoma are improved.
Owner:SHANDONG UNIV

Thyroid ultrasound image nodule segmentation method based on spatial-temporal characteristics and frequency enhancement

The invention discloses a thyroid ultrasound image nodule segmentation method based on spatio-temporal characteristics and frequency enhancement, and relates to the technical field of medical image processing, and the method comprises the following specific steps: multi-scale characteristic extraction: carrying out the gray normalization and median filtering preprocessing of a thyroid ultrasound image, and carrying out the segmentation of the thyroid ultrasound image nodule; extracting multi-scale features under different resolutions by using a pre-trained backbone network, obtaining the multi-scale features under different resolutions by the backbone network through multilayer convolution and pooling operation, and generating basic and advanced features through convolution operation; by designing an intra-frame feature extraction architecture based on frequency feature fusion and an efficient spatial-temporal feature aggregation mechanism, intra-frame and inter-frame collaborative optimization is realized, intra-frame and inter-frame high and low frequency features are solved by means of octave convolution, the perceptual ability of a model to ultrasonic image details and semantic information is improved, inter-frame and inter-frame feature fusion is realized, and the perceptual ability of the model to ultrasonic image details and semantic information is improved. A local circulation neighborhood propagation mechanism is adopted, and interference of thyroid movement on time sequence feature extraction is effectively restrained.
Owner:SICHUAN UNIV

Intelligent thyroid ultrasound diagnosis report generation method based on multi-modal large language model

The invention discloses a thyroid ultrasound diagnosis report intelligent generation method based on a multi-mode large language model, and relates to a thyroid ultrasound diagnosis report intelligent generation method. The objective of the invention is to solve the problems of lack of term standardization and insufficient complex focus feature analysis in the prior art. According to the method, a full-flow technical system of double-flow coding, cross-modal alignment, dynamic man-machine cooperation and multi-dimensional evaluation is constructed. Multi-scale feature fusion of a thyroid global form and a nodule ROI region is realized through ResNet-50 and ConvNeXt double-flow coding networks, image-text semantic alignment is optimized by adopting a CLIP symmetry loss function, and training resource consumption is reduced in combination with an LoRA parameter fine tuning technology. A dynamic man-machine collaborative closed-loop mechanism is innovatively introduced, model parameters are iteratively optimized through doctor correction data, and a four-dimensional clinical evaluation system comprising ROUGE-L, BLEU-4, CIDEr and expert blind evaluation is established. The invention belongs to the technical field of medical artificial intelligence auxiliary diagnosis.
Owner:HARBIN INST OF TECH +1

Thyroid nodule image classification method and imaging method

PendingCN120526205AImage enhancementImage analysisNodular thyroidRadiology
The invention discloses a thyroid nodule image classification method. The thyroid nodule image classification method comprises the steps of obtaining an image of an existing thyroid part and performing preprocessing to construct a training data set; constructing a thyroid nodule image classification initial model based on the convolution module, the attention mechanism and the full connection layer, and training to obtain a thyroid nodule image classification model; and classifying actual thyroid nodule images by using the obtained thyroid nodule image classification model. The invention also discloses an imaging method comprising the thyroid nodule image classification method. The thyroid nodule image classification model is constructed and trained based on the convolution module, the attention mechanism and the full connection layer, classification and imaging of the thyroid nodule images are achieved, and the thyroid nodule image classification method is higher in reliability, better in accuracy and better in applicability.
Owner:CENT SOUTH UNIV

Thyroid whole-cycle health management method

The invention relates to the field of medical health management, and discloses a thyroid-oriented whole-cycle health management method, which comprises the following steps of: firstly obtaining thyroid multi-source information data of a target population to form a data set, then extracting fusion features to generate a time sequence feature vector, and analyzing and calculating occurrence risk factors and scores of feature dimensions in a preset time window according to the time sequence feature vector; a comprehensive risk score is obtained through time sequence analysis, risk grades are divided, high-risk individuals are marked, and a personalized screening strategy is generated; then combining historical data of high-risk individuals, analyzing key driving paths with high risk scores, associating an external knowledge base to predict recurrence frequency, and finally dynamically adjusting and optimizing screening and intervention strategies according to the recurrence frequency; precise evaluation, grading and personalized management of individual thyroid health risks are achieved, then risk key driving paths are found out, recurrence is predicted, and the strategy is dynamically optimized to improve the disease prevention and treatment effect.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Lysosomal targeting bifunctional molecules for degradation of thyroid stimulating hormone receptor autoantibodies

The present disclosure provides lysosomal targeting bifunctional molecules that target disease causing anti-TSHR autoantibodies for degradation. The lysosomal targeting bifunctional molecules include a ligand moiety that specifically binds to an asialoglycoprotein receptor (ASGPR), and which is linked via a carrier protein to a thyroid stimulating hormone receptor (TSHR) polypeptide that specifically binds target anti-TSHR autoantibodies.
Owner:LYCIA THERAPEUTICS INC

Thyroid-related eye disease intraorbital soft tissue volume measurement method and system

The invention provides a thyroid-related eye disease intraorbital soft tissue volume measurement method and system, and is applied to the technical field of data processing. Three-dimensional medical image data and system abnormal state information are obtained, the three-dimensional medical image data comprise CT images and MRI images, and the system abnormal state information comprises artifacts, isolated noisy points and irregular boundaries; data preprocessing is carried out on the three-dimensional medical image data, standardized image data is generated, and the standardized image data is formed by carrying out ternary processing on spatial registration, noise suppression and gray level normalization; processing the standardized image data and the system abnormal state information to generate an initial segmentation mask; processing the initial segmentation mask to generate an optimized mask; processing the optimized mask and the three-dimensional medical image data to generate soft tissue volume data; and processing the soft tissue volume data, the system abnormal state information and the historical volume data to generate a volume dynamic change report.
Owner:PEKING UNIVERSITY THIRD HOSPITAL (THE THIRD CLINICAL MEDICAL SCHOOL OF PEKING UNIVERSITY)

SH1 homologous cluster fully human TSH receptor blocking monoclonal antibody group as well as preparation method and application of SH1 homologous cluster fully human TSH receptor blocking monoclonal antibody group

The invention discloses a group of blocking monoclonal antibodies of an SH1 homologous cluster fully human thyrotropin receptor (TSHR) (a TSH receptor, TSHR) as well as a preparation method and application of the blocking monoclonal antibodies of the SH1 homologous cluster fully human thyrotropin receptor (TSHR). The method comprises the following steps: sorting plasma cells and memory single B cells for specifically recognizing TSHR in peripheral blood of a patient with high TSH receptor blocking antibody (TBAb) titer by using flow cytometry, cloning antibody light and heavy chains in vitro and performing recombinant expression, and performing antibody property screening verification by using hTSHR-CHO cells. The blocking monoclonal antibody specifically targeting the human TSHR is obtained. The fully human TSH receptor blocking monoclonal antibody disclosed by the invention can be specifically combined with TSHR, and can effectively block signal transduction after the TSH is combined with the receptor; the synthesis and secretion of thyroid hormone are inhibited; expression and fibrosis of effector cell orbital fibroblasts TSHR for inhibiting thyroid-related eye diseases are remarkably relieved, and wide application prospects are achieved in treatment of Graves' diseases and diseases such as thyroid eye diseases caused by hyperthyroidism.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Thyroid ultrasound-assisted diagnosis method and system based on text-driven visual pre-training and cross-modal feature fusion

The invention belongs to the cross field of multiple subjects such as artificial intelligence, computer vision, natural language processing and medical image processing, and discloses a thyroid ultrasound-assisted diagnosis method and system based on text-driven vision pre-training and cross-modal feature fusion. Wherein the model building and training stage comprises the following steps of: preprocessing to obtain an unlabeled image-text pair data set and a labeled image-text pair data set; an image encoder and a text encoder are constructed, pre-training is carried out, and text-driven visual pre-training is realized; using a cross-modal splicing attention fusion module (CMCAF) to realize fusion of text features and image features, inputting the fused text features and image features to a full-connection layer classifier, and performing training optimization through supervision; the application stage is to predict benign and malignant thyroid nodules for the to-be-predicted image-text pairs. The medical image multi-modal fusion method has the advantages of high accuracy, low dependence on pathological labels, high model interpretability, good clinical deployment feasibility and the like, and the problem of the existing AI model in the aspect of medical image multi-modal fusion is effectively solved.
Owner:HUAZHONG UNIV OF SCI & TECH

Thyroid-related eye disease auxiliary verification method based on SPECT / CT and federated learning

PendingCN120689316AImage enhancementImage analysisExtraocular musclesAccurate segmentation
The invention discloses a thyroid-related eye disease auxiliary verification method based on SPECT / CT and federal learning. The thyroid-related eye disease auxiliary verification method comprises the steps that A, image data standardization and orbit area extraction are carried out; b, extracting a preliminary segmentation mask of each rectus in the CT image; c, fusing the structure prior mask, and obtaining an extraocular muscle fine segmentation mask through multi-mode collaborative segmentation; d, utilizing extraocular muscle fine segmentation masks, SPECT and CT images, fusing segmentation prior and multi-modal features to perform deep discrimination, performing automatic prediction of thyroid-related eye disease activity staging, and outputting a prediction probability; and E, based on a dynamic model combination strategy of style similarity and uncertainty quantization, obtaining a dynamic combination model of segmentation and classification adapted to new domain feature distribution, and predicting TAO activity. According to the method, accurate segmentation of extraocular muscle structures and accurate prediction of TAO activity in an invisible data center can be realized, auxiliary verification data support is provided for diagnosis of thyroid-related eye diseases, and the diagnosis accuracy is improved.
Owner:ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

Thyroid tumor evaluation system based on combination of ultrasonic image and pathological data

The invention discloses a thyroid tumor evaluation system based on combination of an ultrasonic image and pathological data, and relates to the technical field of auxiliary decision making. Comprising the steps that an image acquisition module preprocesses a thyroid ultrasound image; the pathology acquisition module is used for extracting structured data containing pathology malignancy scores and molecular marker expression parameters; the feature extraction module generates feature vectors from the images and the pathological data respectively; the region screening module dynamically generates an image region sensitivity threshold value based on the molecular marker and the pathological malignant score; a weighted extraction module recognizes an image suspicious region and generates weighted features according to the image suspicious region; the multi-modal fusion module fuses bimodal features through a weight distribution rule; and the evaluation decision module outputs benign and malignant prediction results and confidence scores. Dynamic sensitivity regulation and control of deep coupling of pathological semantics and image features are realized, and image suspicious region identification precision and cross-modal decision reliability precision are improved.
Owner:THE THIRD PEOPLES HOSPITAL OF CHENGDU

Lightweight multi-feature fusion thyroid nodule classification method

The invention discloses a lightweight multi-feature fusion thyroid nodule classification method. Relates to the technical field of medical image processing, in particular to the technical field of a lightweight multi-feature fusion thyroid nodule classification method. According to the method, the Hifuse model is improved, so that the parameter quantity and the calculation complexity can be reduced while the global features and the local features of the image are fully mined and the benign and malignant thyroid nodules are comprehensively discriminated in a multi-view and multi-azimuth manner. The method comprises the following steps: acquiring and preprocessing a thyroid nodule ultrasonic diagnosis report image data set; a Hifuse model is constructed and improved; a radiomics feature learning module is introduced into the Hifuse model, the local attention module is replaced by the improved local attention module, and the global attention module is replaced by an Officient ViM global extraction module; and completing thyroid nodule classification by adopting the trained Hifuse improved model.
Owner:CHANGCHUN UNIV OF SCI & TECH

Recognition method for recurrent laryngeal nerves and adjacent anatomical structures thereof in ultrasonic image

The invention relates to the technical field of medical information processing, and particularly discloses a method for identifying a recurrent laryngeal nerve and an adjacent anatomical structure thereof in an ultrasonic image, and the method comprises the steps: obtaining a two-dimensional thyroid region ultrasonic image, and carrying out the fine marking of the recurrent laryngeal nerve, the true thyroid envelope, the false thyroid envelope and the connective tissue; performing uniform size adjustment, normalization and data enhancement on the marked image; performing semantic segmentation on the image to obtain a segmented image containing the recurrent laryngeal nerve and an adjacent anatomical structure region; extracting depth features of the local structure of the segmented image; extracting high-dimensional geometric structure features of the segmented image; fusing the extracted features to form a comprehensive feature vector; and inputting the fused comprehensive feature vector into a classification module to perform automatic classification and identification of the recurrent laryngeal nerve and the adjacent structure thereof. According to the invention, the recognition accuracy and stability in the ultrasonic image can be improved.
Owner:PEKING UNIVERSITY THIRD HOSPITAL (THE THIRD CLINICAL MEDICAL SCHOOL OF PEKING UNIVERSITY)

Second-level subclinical hypothyroidism screening model construction method based on conventional physical examination data

The invention discloses a method for constructing a secondary subclinical hypothyroidism screening model based on conventional physical examination data, which comprises the following steps of: constructing a high-quality data set containing the conventional physical examination data, and defining a sample tag in the high-quality data set as a G2SCH positive group or negative group; performing feature selection on the data set by adopting different feature selection methods, and screening out key feature subsets; an oversampling method is adopted to synthesize minority class samples in the data set according to different class balance proportions; adopting a plurality of machine learning algorithms to carry out model prediction training with sample labels as supervision on the basis of data sets of different classes of balance proportions and different key feature subsets, and constructing a plurality of candidate G2SCH screening models; and evaluating and selecting an optimal G2SCH screening model. According to the method, G2SCH screening can be carried out based on conventional physical examination data, dependence on thyroid hormone specialized detection indexes in an existing medical scene is overcome, and the method is suitable for the medical scene with limited resources.
Owner:ZHEJIANG UNIV

Thyroid nodule segmentation system based on dynamic fusion of multi-echo features

The invention discloses a thyroid nodule segmentation system capable of dynamically fusing multi-echo features, relates to the technical field of artificial intelligence and ultrasonic image analysis, and realizes accurate identification and segmentation of thyroid nodule multi-echo types through cooperative work of three feature branches of low echo, high echo and equal echo. A special feature extraction module is designed for each branch for a specific echo type, the extraction process of different echo nodule features is optimized, the capturing capability of key features is enhanced, and the adaptability of the model to a complex ultrasonic image is remarkably improved; according to the method, adaptive weight distribution of different echo type features is realized through attention weighted fusion of the multi-modal feature maps, the mechanism generates attention weights by using a double-layer full-connection network, and weighted fusion is performed on the feature maps after Softmax normalization, so that the problem of fixed weight or lack of adaptability in a traditional feature fusion method is solved.
Owner:四川脉得影深信息技术有限公司

Thyroid eye disease activity evaluation method and system based on eye image

InactiveCN121329947AImage enhancementImage analysisGraves' ophthalmopathyFeature extraction
The invention discloses a thyroid eye disease activity evaluation method and system based on an eye image, and aims to solve the problems that the existing clinical activity score cannot reflect continuous change of an illness state and is susceptible to subjective influence. The method comprises the following steps: acquiring original image data containing an eye region; performing standardized preprocessing on the image data; extracting multi-scale inflammatory features and structural features from the preprocessed image; carrying out cross-modal fusion on the extracted multi-scale features; calculating an activity quantitative score based on the fused comprehensive features; and outputting a visual report of the quantitative score and the evaluation conclusion. The system comprises an image acquisition module, an image preprocessing module, a feature extraction module, a feature fusion module, an activity evaluation module and a result output module. According to the technical scheme, objective quantitative evaluation of thyroid eye disease activity can be achieved, the consistency and repeatability of evaluation results are improved, remote image acquisition and automatic analysis are supported, and the space-time limitation of traditional clinical evaluation is broken through.
Owner:EYE HOSPITAL AFFILIATED TO NANCHANG UNIV

ETE detection method and ETE detection device

An ETE detection method is disclosed. The ETE detection method according to the present invention comprises the steps of: providing an ultrasound image to a first learning model pre-trained to extract a thyroid region, thereby acquiring a first boundary of the thyroid, and providing the ultrasound image to a second learning model pre-trained to extract a nodule region, thereby acquiring a second boundary of a nodule; and outputting a superimposed image in which the first boundary and the second boundary overlap, thereby enabling ETE detection.
Owner:KT CORP

Methods of reducing side effects associated with thyroid

PendingCN121695155AOrganic active ingredientsMetabolism disorderSide effectThyroid Hormone Receptor Agonists
The present disclosure relates to methods of administering thyroid hormone receptor agonists. The present disclosure provides methods wherein the methods maintain the activity of a given thyroid receptor agonist in ameliorating or curing obesity, hyperlipidemia, hypercholesterolemia, diabetes, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, atherosclerosis, cardiovascular disease, hypothyroidism, and related conditions, meanwhile, thyroid-related and thyroid axis-related side effects are reduced or eliminated.
Owner:VIKING THERAPEUTICS INC +1

Thyroid nodule home intervention system and method based on AR navigation and DRL

The invention discloses a thyroid nodule home intervention system and method based on AR navigation and DRL, and relates to the technical field of thyroid nodule home management and intervention.The thyroid nodule home intervention system based on AR navigation and DRL comprises a client module arranged on a user mobile terminal and used for carrying out thyroid nodule home intervention on a thyroid nodule; the guiding module is used for guiding a user to perform self-operation in a home environment, collecting data and receiving feedback; the cloud service module is in communication connection with the client module through the Internet and is used for remote data processing, model operation and personalized intervention scheme management; according to the thyroid nodule home management system, an innovative system of thyroid nodule home management is constructed through cooperation of multiple modules, that is, the maximum acupuncture point positioning error is 3 mm through an AR navigation unit of a client by means of facial feature point fitting and a neck statistical shape model, and the problem that acupuncture points are not found accurately in traditional home operation is solved.
Owner:SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL