Application of theaflavin in preparation of anti-streptococcus suis medicine

The technology of streptococcus suis and theaflavins is applied in the directions of antibacterial drugs, pharmaceutical formulations, medical preparations containing active ingredients, etc., to achieve good antibacterial effect and good application prospect.

Pending Publication Date: 2022-04-08
INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the antibacterial effects of theaflavins

Method used

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  • Application of theaflavin in preparation of anti-streptococcus suis medicine
  • Application of theaflavin in preparation of anti-streptococcus suis medicine
  • Application of theaflavin in preparation of anti-streptococcus suis medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Antibacterial spectrum determination of theaflavins on bacteria:

[0018] 1. Materials

[0019] Mueller-Hinton (MH) broth (purchased from BD Company) was used in drug susceptibility experiments to detect the antibacterial efficacy of drugs.

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Abstract

The invention belongs to the technical field of veterinary drugs, and discloses application of theaflavin in preparation of anti-streptococcus suis drugs. The applicant discovers that the theaflavin has the effects of inhibiting the growth of streptococcus suis and killing the streptococcus suis, the minimum inhibitory concentration of the theaflavin to the streptococcus suis is 512 mu g / ml, the minimum bactericidal concentration of the theaflavin to the streptococcus suis is 2048 mu g / ml, the toxic and side effects of vaccines, chemical drugs and antibiotics and potential food safety hazards are overcome, and the theaflavin has wide application prospects and development values in the fields of food processing, medicine and breeding industry.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to the application of theaflavin in the preparation of anti-Streptococcus suis medicine. Background technique [0002] Streptococcus suis is a zoonotic infectious disease pathogen, which can cause meningitis, sepsis, arthritis, endocarditis, pneumonia, and even death of pigs and humans. Streptococcus suis not only causes significant economic losses to the pig industry, but also poses a huge threat to human public health. According to the specificity of bacterial capsular polysaccharide antigens, Streptococcus suis is divided into 33 serotypes. Among the many serotypes, Streptococcus suis type 2, type 7, and Streptococcus equi zooepidemic subspecies are often isolated from sick and dead pigs. out of the dominant serotype. [0003] The focus of control of Streptococcus suis is prevention and antibiotic treatment. However, there are many serotypes of Streptoc...

Claims

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Application Information

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IPC IPC(8): A61K31/353A61P31/04
Inventor 高婷田永祥袁芳艳叶飞刘泽文刘威周丹娜杨克礼郭锐谭美芳
Owner INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI
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