Medicine for resisting tuberculosis and preparation method

A tuberculosis and drug technology, applied in the field of anti-tuberculosis drugs and their preparation, can solve the problems of long course of treatment, allergic reactions, toxic and side effects, etc.

Inactive Publication Date: 2003-08-27
姚明波
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

These medicines have obvious disadvantages: one, the course of treatment of these medicines is too long, and the full course of treatment of newly treated smear-negative patients and smear-negative patients needs 6 months, and the full course of treatment of re-treated smear-positive patients needs 8 months; The toxic and side effects are relatively large. Isoniazid and rifampin have toxic and side effects of liver toxicity, gastrointestinal reactions and allergic reactions on average. Pyrazinamide also has toxic and side effects, gastrointestinal reactions, and gouty arthritis. Etamine Alcohol has vision impairment, allergic reaction, and streptomycin has toxic and side effects such as hearing impairment, dizziness, renal dysfunction, anaphylaxis; 3, adopt these medicines to treat, and the expenditure of patient is big, because the course of treatment is long, needs multiple medicine combination again Use, or even use of expensive second-line drugs other than the above-mentioned drugs, resulting in excessive expenditure for patients, which is unaffordable

Method used

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Embodiment Construction

[0004] The preparation method and other details of the medicine of the present invention will be described in detail below. First mix dry mylabris and glutinous rice in a weight ratio of 1:10, fry in an iron pan until the glutinous rice turns brown, and after cooling, take out the cantharidin and remove the head, feet, and wings, crush and sieve (70 mesh) into the cantharidin pink. Then open the chicken eggs, remove the egg yolk, take the net protein juice to induce protein, and then grind the dried hibiscus leaves into powder. The traditional Chinese medicine name of the powder is Yulusan. Its original juice, that is, Yulu juice, is used as an excipient. In this way, the mylabris (monarch drug) with strong anti-tuberculosis properties is stirred and detoxified by glutinous rice (minister drug), and the anti-inflammatory and detoxifying effect of Yulu juice (adjuvant drug) is added. The medicinal effect is matched according to the monarch, minister, assistant, and envoy in t...

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Abstract

The present invention discloses a medicine for curing tuberculous diseases of pulmonary tuberculosis, lymphoid tuberculosis, tuberculosis of spine and intrathoracic tubeculosis and its preparation method. Its main composition comprises (wt%) 1.9512% of mylabris powder, 97.56% of induced protein and 0.04878% of excipient. Its preparation method includes the following steps: placing the mylabris powder into induced protein, uniformly stirring and low-temp. storing, then steaming them, cooling, pulverizing, drying, sieving, adding excipient, making them into small granules, drying.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to an anti-tuberculosis medicine and a preparation method thereof. Background technique [0002] In the prior art, my country adopts the chemotherapy regimen recommended by the World Health Organization and combined with my country's practical experience in the treatment of tuberculosis. The main drugs used are isoniazid (H), rifampicin (R), pyrazinamide (Z), ethambutol (E) or streptomycin (S). These medicines have obvious disadvantages: one, the course of treatment of these medicines is too long, and the full course of treatment of newly treated smear-negative patients and smear-negative patients needs 6 months, and the full course of treatment of re-treated smear-positive patients needs 8 months; The toxic and side effects are relatively large. Isoniazid and rifampin have toxic and side effects of liver toxicity, gastrointestinal reactions and allergic reac...

Claims

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Application Information

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IPC IPC(8): A61K38/17A61P31/06
Inventor 姚明波
Owner 姚明波
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