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Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance

A technology for aspirin and a composition is applied in the application field of preparing medicines for treating aspirin resistance, and can solve problems such as unreported

Active Publication Date: 2005-07-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0026] There is no report about the drug composition in the treatment of aspirin resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0103] Take 1200g of Danshen, 1200g of Panax notoginseng, and 10.5ml of balsamic oil;

[0104] The above three flavors and Danshen are extracted twice with ethanol, each time for 70 minutes, filtered, the filtrates are combined, the ethanol is recovered and concentrated to a clear paste with a relative density of 1.20-1.25 (measured at 60°C), and set aside; Panax notoginseng is crushed into a coarse powder, 70% ethanol reflux extraction twice, each 1.5 hours, combined extracts, filtered, the filtrate reclaimed ethanol, and continued to concentrate to a clear paste with a relative density of 1.20-1.25 (measured at 60°C), adding a small amount of diatomaceous earth, ( 80°C) concentrated under reduced pressure to a clear paste with a relative density of 1.20-1.25 (measured at 60°C), and set aside; heat polyethylene glycol 6000 on a water bath until completely melted, then add the above-mentioned salvia miltiorrhiza and Panax notoginseng extract, stir well, After cooling down slig...

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PUM

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Abstract

The invention relates to the application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance, wherein the composition comprises (by weight ratio) Chinese angelica root 10-100mg, astragalus root 50-100mg, red peony root 10-50g, Ligusticum wallichii 20-100g, radix salvia miltiorrhiza 60-300g, cassia twig 10-100g, peach kernel 10-100g, safflower 10-100g, mulberry twigs 10-200g, achyranthes and cyathula root 10-200g, frankincense 10-150g, myrrh 10-150g, hooked uncaria 10-200g, earthworm 10-500g, buthus martensi kirsch 10-1000g, centipede 1-100 pieces, spatholobus stem 10-500g, leech 10-1000g.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a pharmaceutical composition in the preparation of medicines for treating aspirin resistance. Background technique [0002] Aspirin (Aspirin), also aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when asp...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61P9/10
Inventor 吴迺峰郭治忻范立君郑军郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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