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Application of pharmaceutical composition in the process for preparing medicine to counteract aspirin resisting medicine

A technology of aspirin and composition, which is applied in the application field of preparing anti-aspirin resistance drugs, and can solve problems that have not been reported yet

Active Publication Date: 2009-10-28
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0026] However, there is no report on the research on the drug composition for the treatment of "aspirin resistance".

Method used

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  • Application of pharmaceutical composition in the process for preparing medicine to counteract aspirin resisting medicine
  • Application of pharmaceutical composition in the process for preparing medicine to counteract aspirin resisting medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Take the Radix Paeoniae Alba in the amount of raw materials, add water and decoct 2-4 times, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.20-1.50 (50°C), dry, powder into fine powder, and then add the Ginseng stem and leaf saponins and 20-80 weight units of stevioside fine powder (sweetener) and 1-10 weight units of starch are granulated with 60%-80% ethanol, dried, and packed into capsules (each About 0.25g of medicine is filled in the capsule), and the product is obtained.

Embodiment 2

[0052] Take the Radix Paeoniae Alba in the amount of raw materials, add water and decoct 2-4 times, combine the decoction, filter, concentrate the filtrate under reduced pressure to a relative density of 1.20-1.50 (50°C), dry, powder into fine powder, and then add it to the amount of raw materials in turn Ginseng stem and leaf saponins and 20-60 weight units of stevioside fine powder (sweetener) and 1-10 weight units of starch are granulated with 60%-80% ethanol, dried, and magnesium stearate is added 1-5 weight units, mixed evenly, pressed into tablets (core weight 0.39 / tablet), and then coating the core with sugar (15-20kg of white granulated sugar for each kg of tablet core, 14-20kg of talcum powder, polished) , the product is obtained.

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Abstract

The invention relates to the application of a pharmaceutical composition in the preparation of medicines for treating aspirin resistance. The composition of the medicine is as follows according to weight ratio: 8-20 weight units of ginseng stem and leaf saponin, and 1000-2500 weight units of white peony root.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition in the preparation of anti-aspirin resistance drugs. Background technique [0002] Aspirin (Aspirin), also aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth research on prostaglandins, new understandings have been gained on aspirin: in addition to being traditionally used for antipyretic, analgesic and anti-inflammatory, it is also used for anti-platelet aggregation in clinical practice. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin is used in thera...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K36/258A61K9/00A61P9/10
Inventor 吴迺峰郭治忻范立君郑军郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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