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Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resisting disease

A composition, aspirin technology, applied in the field of medicine, can solve problems such as unreported

Active Publication Date: 2008-04-16
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0026] However, there is no report on the effect of the drug composition on aspirin resistance

Method used

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  • Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resisting disease
  • Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resisting disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] a. Take 450g of salvia miltiorrhiza, 141g of notoginseng, and 8g of borneol;

[0054] b. Extract Salvia miltiorrhiza 3 times in the following manner: heat and reflux with ethanol for 1.5 hours, filter, recover ethanol, concentrate the filtrate to form a concentrated solution with a relative density of 1.30 (55-60°C); heat and reflux the remaining medicinal materials with 50% ethanol for 1.5 hours, filter;

[0055] Continue to add water to reflux and heat the medicinal material for 2 hours, and filter. Combine the second and third extracts, recover ethanol, concentrate to a relative density of 1.40 (55-60°C), combine with the concentrated solution extracted for the first time, and make an infusion with a relative density of 1.35-1.39 (55-60°C). paste.

[0056] c. Grinding Panax notoginseng, mixing the above-mentioned concentrated salvia miltiorrhiza extract, drying into granules.

[0057] d. Grind borneol into fine powder, mix with the above granules, and make 1000 pi...

Embodiment 2

[0059] a. Take 450g of salvia miltiorrhiza, 141g of notoginseng, and 8g of borneol;

[0060] b. Extract Salvia miltiorrhiza 3 times in the following manner: heat and reflux with ethanol for 1.5 hours, filter, recover ethanol, concentrate the filtrate to form a concentrated solution with a relative density of 1.30 (55-60°C); heat and reflux the remaining medicinal materials with 50% ethanol for 1.5 hours, filter;

[0061] Continue to add water to reflux and heat the medicinal material for 2 hours, and filter. Combine the second and third extracts, recover ethanol, concentrate to a relative density of 1.40 (55-60°C), combine with the concentrated solution extracted for the first time, and make an infusion with a relative density of 1.35-1.39 (55-60°C). paste.

[0062] c. Grinding Panax notoginseng, mixing the above-mentioned concentrated salvia miltiorrhiza extract, drying into granules.

[0063] d. Grind borneol into fine powder, mix with the above granules, make 1000 pieces...

Embodiment 3

[0065] a. Take 480g of salvia miltiorrhiza, 130g of notoginseng, and 7g of borneol;

[0066] b. Extract Salvia miltiorrhiza 3 times in the following manner: heat and reflux with ethanol for 1.5 hours, filter, recover ethanol, concentrate the filtrate to form a concentrated solution with a relative density of 1.30 (55-60°C); heat and reflux the remaining medicinal materials with 50% ethanol for 1.5 hours, filter;

[0067]Continue to add water to reflux and heat the medicinal material for 2 hours, and filter. Combine the second and third extracts, recover ethanol, concentrate to a relative density of 1.40 (55-60°C), combine with the concentrated solution extracted for the first time, and make an infusion with a relative density of 1.35-1.39 (55-60°C). paste.

[0068] c. Grinding Panax notoginseng, mixing the above-mentioned concentrated salvia miltiorrhiza extract, drying into granules.

[0069] d. Grind borneol into fine powder, mix with the above granules, make 1000 pieces,...

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Abstract

The invention relates to the application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance, wherein pharmaceutical composition comprises (by weight ratio) root of red rooted saliva 50-60 parts, notoginseng 16-20 parts, borneol 0.1-3 parts, the composition can be prepared into any of the pharmacologically acceptable dose form.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a pharmaceutical composition in the preparation of medicines for treating aspirin resistance. Background technique [0002] Aspirin (Aspirin), also aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth research on prostaglandins, new understandings have been gained on aspirin: in addition to being traditionally used for antipyretic, analgesic and anti-inflammatory, it is also used for anti-platelet aggregation in clinical practice. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin is used in thera...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61K36/258A61K31/045A61K9/00A61P9/10
Inventor 吴迺峰郭治忻范立君郑军郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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