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Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance

A technology for aspirin and a composition is applied in the application field of preparing anti-aspirin-resistance drugs, and can solve the problems that the aspirin-resistance effect has not yet been reported.

Active Publication Date: 2008-04-16
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0025] However, there is no report about the drug composition in the treatment of aspirin resistance

Method used

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  • Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance
  • Application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance

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Experimental program
Comparison scheme
Effect test

Embodiment

[0049] First extract 35g of ginkgo leaves with 70% ethanol for 2 times, each time for 2 hours, filter, recover ethanol from the filtrate, and spray dry the concentrated solution to obtain dry powder; hour, 1 hour for the third time, filter, combine the filtrates for 3 times, concentrate to a relative density of 1.20, add ethanol and stir to precipitate, take the supernatant to reclaim ethanol, and spray-dry the concentrated solution to obtain dry powder; time, each time for 2 hours, filtered, the filtrate recovered ethanol, and the concentrated solution was spray-dried to obtain a powder; the moxa tablet was crushed into a fine powder, mixed with the powder prepared in the above three items, added to the melted polyethylene glycol 6000, and stirred Evenly, drop the medicinal liquid into the methyl silicone oil, take out the dropping pills, absorb the coolant, dry, and make 1000 capsules.

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Abstract

The invention relates to the application of pharmaceutical composition in the process for preparing medicine to treat aspirin resistance, wherein the composition comprises (by weight ratio) ginkgo leaves 17-52g, radix salvia miltiorrhiza 22-67g, gynostemma pentaphylla 13-37g, borneol 2.5-7.5g, the composition can be prepared into any of the pharmacologically acceptable dose form.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition in the preparation of anti-aspirin resistance drugs. Background technique [0002] Aspirin (Aspirin), also aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth research on prostaglandins, new understandings have been gained on aspirin: in addition to being traditionally used for antipyretic, analgesic and anti-inflammatory, it is also used for anti-platelet aggregation in clinical practice. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin is used in thera...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61K36/424A61K36/282A61K36/16A61K9/00A61P9/10
Inventor 吴迺峰郭治忻范立君郑军郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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