The invention discloses fruit wine for preventing cardiovascular diseases prepared via a special method. The fruit wine is prepared by: crushing, by weight, 50-60 parts of fresh lemon fruit, 40-50 parts of raisin tree fruit and 5-20 parts of rose flower, stirring for homogenizing, adding an enzyme, and enzymatically hydrolyzing by warm bath at 37 DEG C; filtering to obtain enzymatic hydrolytic filtrates, combining the enzymatic hydrolytic filtrates, and adjusting pH to 3-5 to obtain mixed fruit juice at sugar degree of 16-20%; sterilizing the mixed fruit juice, adding Rhizopus, aroma-producing yeast, activated dry yeast and lactic acid bacteria, and fermenting for 15-20 days to obtain fermentation broth; adding an enzyme to the fermentation broth, enzymatically hydrolyzing again, filtering, and ageing the filtrate to obtain the target fruit wine. The fruit wine has unique flavor, can lower blood lipid, and can well change blood viscosity and prevent cardiovascular diseases; compared with Baijiu or common fruit wine having the same alcohol by volume, the fruit wine allows ethanol and acetaldehyde in the body to be cleared efficiently and quickly after being drunk, can cause very little harm to the liver, and may be drunk often as functional fruit wine to prevent cardiovascular diseases.