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Method for preparing compound Folium pyrrosial particles and its quality control technology

A technology of compound shiwei and granules, which is applied in the field of preparation of compound shiwei granules, which can solve problems such as inconsistent properties, difficult absorption, and slow tablet disintegration process

Inactive Publication Date: 2006-05-24
葵花药业集团(襄阳)隆中有限公司
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Problems solved by technology

The original dosage form tablet and its preparation process have the following deficiencies: ①The disintegration process of the tablet is slow, and it is not easy to absorb; Extraction preparation does not match the properties of the main active ingredients contained in each medicine, the extraction efficiency is not high and contains a large amount of invalid ingredients

Method used

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  • Method for preparing compound Folium pyrrosial particles and its quality control technology

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Experimental program
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Embodiment Construction

[0011] See Figure 1.

[0012] [Prescription] Shiwei 740g  Storage 740g Sophora flavescens 740g Astragalus 740g

[0013] [Preparation method] Take the above four flavors, take Sophora flavescens, 715g Shiwei, 690g Astragalus, and 715g 益, add 8 times the amount of water to decoct twice, the first time for 2 hours, the second time for 1 hour, filter, and the filtrate Compress and condense into a clear paste with a relative density of 1.30~1.35 (60°C heat test), and take another 25g of Shiwei, 50g of Radix Astragali, and 25g of 益, and grind them into fine powder, then add 575g of dextrin and 25g of stevioside, and mix with the above clear paste Uniformly made into soft materials, made into granules, dried, and made into 1000g, that is to say.

[0014] 【Properties】This product is yellow-brown to tan granules; tastes slightly sweet and slightly bitter.

[0015] [Identification] (1) Take 10g of this product, grind it finely, add 50ml of methanol to reflux extraction twice, each ...

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Abstract

The present invention provides a preparation method of compound pyrrosia granules and its quality control technique. Its raw material composition includes four Chinese medicinal materials of pyrrosia leaf, astragalus root, flavescent sophora root and knotgrass. In its production process the stevioside can be added as sweetening agent.

Description

technical field [0001] The invention relates to a preparation method and quality control technology of compound Shiwei granules. technical background [0002] Compound Shiwei Tablets are the varieties included in the fifteenth volume of standard traditional Chinese medicine preparations issued by the State Drug Administration (the fifteenth volume of drug standards for traditional Chinese medicine preparations issued by the former Ministry of Health). ,  is composed of four herbs, which has the effects of clearing away heat and dampness, diuresis and treating stranguria. The original dosage form tablet and its preparation process have the following deficiencies: ①The disintegration process of the tablet is slow, and it is not easy to absorb; The extraction preparation is inconsistent with the properties of the main active ingredients contained in each medicine, the extraction efficiency is not high and contains a large amount of invalid ingredients. Contents of the inven...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K9/16A61P7/10G01N30/02G01N30/90G01N33/15
Inventor 余世春
Owner 葵花药业集团(襄阳)隆中有限公司
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