Antidepressants or food and drinks for antidepression

Abstract

An object of the present invention is to provide antidepressants or foods and drinks for antidepression. To solve the present problem, the present invention provides antidepressants or foods and drinks for antidepression comprising, as an active ingredient, a compound represented by formula (I): (wherein R 1 , R 2 , R 3 and R 4 , which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, or the like.; R 5 represents a hydrogen atom, hydroxy, or the like.; R 6 represents a hydrogen atom, or the like.; R 7 represents a hydrogen atom or substituted or unsubstituted lower alkyl; and R 8 , R 9 , R 10 and R 11 , which may be the same or different, each represent a hydrogen atom or substituted or unsubstituted lower alkyl) or a salt thereof.

Description

technical field [0001] The present invention relates to an antidepressant or an antidepressant food and drink. Background technique [0002] As antidepressants, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants such as amitriptyline and imipramine, and tetracyclic antidepressants such as mianserin and maprotiline have been used. However, MAO inhibitors have side effects such as liver damage, hyperstimulant action, toxic psychosis, insomnia, orthostatic hypotension, dizziness, tinnitus, and constipation. Tricyclic antidepressants have drowsiness, malaise, anticholinergic effects (thirst, constipation, dysuria, tachycardia, glaucoma exacerbation, etc.), orthostatic hypotension, liver damage, rash, delirium, dizziness, convulsions and other side effects. Tetracyclic antidepressants have problems of side effects such as convulsions, drug eruption, drowsiness, and neutropenia. On the other hand, it has been reported that 5-hydroxytryptamine (5-HT) participates in t...

AI Technical Summary

Problems solved by technology

However, these SSRIs have side effects such as low blood pressure, palpitations, dizziness, staggering, lethargy, rashes, liver damage, fatigue, vomiting, nausea, etc.

Images