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Soft capsule formulation containing gastrodia tuber medicinal composition and preparation method thereof

A soft capsule preparation and soft capsule technology, applied in Tianmatou Fengling soft capsule and its preparation field, can solve the problems of lower patient compliance, inconvenient swallowing, large dosage, etc., and achieve convenient taking, beautiful appearance, and convenient carrying Effect

Inactive Publication Date: 2006-07-12
JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many problems in hard capsules, such as: the water extract of the prescription is very easy to absorb moisture, so the hard capsule preparations have moisture absorption and caking, and the stability is poor; Large and inconvenient to swallow, reducing patient compliance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] prescription:

[0034] Gastrodia elata 100g, Achyranthes bidentata 100g, Scrophulariaceae 100g, Rehmannia glutinosa 300g, Angelica 430g, Eucommia ulmoides 86g, Chuanxiong 100g, mistletoe 430g, wild chrysanthemum 100g, Uncaria 100g.

[0035] Gastrodia elata is crushed into fine powder, passed through a 100-mesh sieve, and set aside;

[0036] Achyranthes bidentata, Scrophulariaceae, Rehmannia glutinosa, Angelica sinensis, Eucommia ulmoides, Chuanxiong, mistletoe, wild chrysanthemum, Uncaria, add 10 times the amount of water, extract 3 times, 2 hours each time, combine the extracts, filter, centrifuge, and concentrate under reduced pressure to a relative Clear paste with a density of 1.00-1.10 (60°C), spray-dried, passed through a 100-mesh sieve, and set aside;

[0037] The above-prepared fine powders are taken, mixed uniformly to obtain active ingredients, mixed with vegetable oil and beeswax, and finally pressed into soft capsules through a soft capsule preparation proc...

Embodiment 2

[0039] prescription:

[0040] Gastrodia elata 100g, Achyranthes bidentata 100g, Scrophulariaceae 100g, Rehmannia glutinosa 300g, Angelica 430g, Eucommia ulmoides 86g, Chuanxiong 100g, mistletoe 430g, wild chrysanthemum 100g, Uncaria 100g.

[0041] Gastrodia elata is crushed into fine powder, passed through a 150-mesh sieve, and set aside;

[0042] Achyranthes bidentata, Scrophulariaceae, Rehmannia glutinosa, Angelica sinensis, Eucommia ulmoides, Chuanxiong, mistletoe, wild chrysanthemum, Uncaria, add 8 times the amount of water, extract 3 times, 1 hour each time, combine the extracts, filter, centrifuge, and concentrate under reduced pressure to obtain a relative Clear paste with a density of 1.10-1.15 (60°C), dry, pulverize, pass through a 150-mesh sieve, and set aside;

[0043] Take each fine powder prepared above, mix evenly to obtain the active ingredient, then mix with polyethylene glycol 400, and finally go through the soft capsule preparation process, such as adding gl...

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PUM

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Abstract

The invention relates to a soft capsule formulation containing gastrodia tuber medicinal composition and preparation method, wherein the capsule is prepared mainly from gastrodia tuber, achyranthes and cyathula root, scrophularia root, dried rehmannia root, Chinese angelica root, eucommia bark, Ligusticum wallichii, stem of mistletoe, wild chrysanthemum flower and hooked uncaria. The soft capsule can be used for treating cephalalgia, chronic extremity anesthesia and chronic soreness of waist.

Description

technical field [0001] The invention relates to Gastrodia elata head Fengling soft capsule and a preparation method thereof, in particular to nourishing yin potential capsules made from Gastrodia elata, Achyranthes bidentata, Scrophulariae scrophulariae, rehmannia glutinosa, angelica, Eucommia ulmoides, Rhizoma Chuanxiong, mistletoe, wild chrysanthemum, and Uncaria The invention discloses a traditional Chinese medicine for yang, expelling wind and relieving pain and a preparation process thereof, belonging to the field of pharmaceutical preparations. Background technique [0002] The Tianmatou Fengling soft capsule of the present invention has its prescription recorded in the Ministry of Health drug standards. Tianmatou Fengling Soft Capsule is a soft capsule preparation improved on this basis. [0003] The traditional Chinese medicine for nourishing yin and subsiding yang, expelling wind and relieving pain made from Gastrodia elata, Achyranthes bidentata, Radix Scrophulari...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K9/48A61P25/06A61P25/04A61P29/00
Inventor 杨士豹刘春晖袁源檀爱民
Owner JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
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