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Application of dripping pills containing astragalus mongholicus and ginseng for treating senile dementia

A technology of Qishen Yiqi Dropping Pill and Alzheimer's Disease, applied in the field of medicine, can solve the problem that the effect of Alzheimer's disease has not yet been reported.

Active Publication Date: 2011-04-27
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN1375316A discloses the composition, preparation method and application of the preparation in coronary heart disease and angina pectoris, but the effect of the drug in the prevention and treatment of senile dementia has not yet been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Take 86.5g of astragalus, 21.3g of salvia miltiorrhiza, 3.5g of notoginseng, 20.6g of jiangxiang, and 30g of polyethylene glycol-6000 as an auxiliary material. Decoct the crushed salvia miltiorrhiza and Panax notoginseng in water twice, adding 7 times the amount of water each time for 2 hours each time, combining the decoction liquid, filtering, and concentrating the filtrate to 900ml, adding 95% ethanol to make the alcohol concentration reach 70%, let it stand for 12-24 hours, filter, recover ethanol, concentrate into an extract with a relative density of 1.32-1.38 (50-60°C); decoct the pulverized Astragalus membranaceus twice with water, adding 6 Double the amount of water, extract for 2 hours and 1 hour in turn, combine the filtrate, and when concentrated to about 1500ml, add 95% ethanol to make the alcohol concentration 60%, let it stand for 12-24 hours, filter, recover ethanol from the filtrate, and concentrate to about 400ml , add 95% ethanol to make the alcohol c...

Embodiment 2

[0036] Get Astragalus 40.6g, Salvia miltiorrhiza 44.8g, Panax notoginseng 11.2g, Dalbergia 38.6g, adjuvant polyethylene glycol-6000 30g, according to the preparation process of embodiment 1, make the traditional Chinese medicine preparation of the present invention.

Embodiment 3

[0038] Get 77.3g of Radix Astragali, 22.8g of Salvia miltiorrhiza, 4.8g of Radix Notoginseng, 30.5g of Jiangxiang, and 28g of polyethylene glycol-6000 as an auxiliary material, and make the traditional Chinese medicine preparation of the present invention according to the preparation process of Example 1.

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Abstract

An application of the 'Qi-replenishing' Qishen dripping pill in preparing the medicines for preventing and treating senile dementia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Qishen Yiqi dripping pills in the preparation of medicaments for preventing and treating senile dementia. Background technique [0002] Senile dementia is a primary degenerative disease of the central nervous system, with a slow onset and a chronic course, with an average of 5-10 years, characterized by comprehensive progressive dementia. Among senile dementias, vascular dementia (Vascular dementia, VD) and Alzheimer's Disease (AD) are the most common. The main manifestations are memory, language, judgment, cognition, thinking, behavior, personality, and emotion and other high-level neural activity disorders, accompanied by aphasia, apraxia, agnosia, agraphia, and dyslexia, etc. Finally, the patient becomes sluggish, dazed, and bedridden , often due to bed sores, malnutrition, pneumonia and other secondary physical diseases, or died of exhaustion. Drugs fo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61K36/481A61K36/48A61K36/258A61K9/20A61P25/28
Inventor 李旭郑永峰叶正良
Owner TIANJIN TASLY PHARMA CO LTD
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