Vitamin dripping pill and its preparing method

A technology for vitamins and dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc. It can solve the problem that emotional control has not been significantly improved, and is beneficial to labor protection, not easy to oxidize, and simple production equipment Effect

Active Publication Date: 2007-04-11
AOLING BODA MEDICINE SCI & TECH DEV BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

B vitamins (B1.B2, B6, B12.) are the vitamins that the human body can feel the most. If you supplement with multi-vitamins containing B vitamins every day, but in a short period of time in fatigue, nervous tension, emotional control, etc. It has not been significantly improved, it is a problem of vitamin absorption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] (1) Formulation:

[0036] Vitamin B1 1000mg Vitamin B2 1000mg Vitamin B12 100mg

[0037] Macrogol 6000 47400mg

[0038] Polyethylene glycol 4000 3160mg tert-butyl-4-hydroxyanisole 2mg

[0039] 3% HPMC coating solution

[0040] Makes 1000 pills

[0041] Specification Vitamin content in formula 2.1mg / pill

[0042] Pill weight 10mg / pill

[0043] (2) Preparation method

[0044] Take 4740mg of polyethylene glycol 6000 and 3160mg of polyethylene glycol 4000, heat and melt, add 2mg of tert-butyl-4-hydroxyanisole, stir well, add 1000mg of vitamin B1, 1000mg of vitamin B2, 100mg of vitamin B12 Fine powder, after mixing evenly to form a uniform dispersion, transfer it to the dripping equipment for dripping, keep warm at 80°C, drop into liquid paraffin (-2°C to -8°C), drop into 1000 pills, wipe the pills, and dry them in the air , coated with 3% HPMC coating solution. Each drop pill contains 2.1mg of vitamins.

Embodiment 2

[0046] (1) Formulation:

[0047] Vitamin B1 1000mg Vitamin B2 1000mg Vitamin B6 1000mg

[0048] Vitamin B12 100mg Vitamin C 5000mg Vitamin E 2000mg

[0049] Macrogol 6000 23940mg Macrogol 4000 15960mg

[0050] 3% HPC coating solution

[0051] Makes 1000 pills

[0052] Specification Vitamin content in formula 10.1mg / pill

[0053] Pill weight 50mg / pill

[0054] (2) Preparation method

[0055] Take 23940mg polyethylene glycol 6000 and 15960mg polyethylene glycol 4000, heat and melt, add 1000mg vitamin B1, 1000mg vitamin B2, 1000mg vitamin B6, 100mg vitamin B12, 5000mg vitamin C fine powder and 2000mg vitamin E viscous liquid, fully After mixing evenly to form a uniform dispersion, transfer it to the dripping equipment for dripping, keep it warm at 80°C, drop it into liquid paraffin (-5°C to -10°C), drop it into 1000 pills, wipe the pills, and dry them in the air.

[0056] Coat with HPC coating solution. Each drop pill contains 10.1mg...

Embodiment 3

[0058] (1) Formulation:

[0059] Vitamin B1 1000mg Vitamin B2 1000mg Vitamin B6 1000mg

[0060] Vitamin B12 200mg Vitamin C 5000mg Vitamin E 2000mg

[0061] Niacin 1000mg Niacinamide 1000mg

[0062] Macrogol 6000 61300mg

[0063] Stearic acid 1500mg 8% PVP coating solution

[0064] Makes 1000 pills

[0065] Specification Vitamin content in formula 12.2mg / pill

[0066] Pill weight 75mg / pill

[0067] (2) Preparation method

[0068] Take 61300mg of polyethylene glycol 6000, heat and melt, add 1000mg of vitamin B1, 1000mg of vitamin B2, 1000mg of vitamin B6, 200mg of vitamin B12, 5000mg of vitamin C, 1000mg of niacin, 1000mg of niacinamide fine powder and 2000mg of vitamin E viscous liquid, After fully mixing to form a uniform dispersion, transfer it to the dripping equipment for dripping, keep warm at 75°C, drop into liquid paraffin (-5°C to -10°C), drop into 1000 pills, wipe the pills, dry them, and use PVP coating solution coating. E...

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PUM

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Abstract

The invention related to vitamin drop pills and its preparation process and belongs to technical field of drug preparation. Its formula consists of vitamin, base material for drop pills, anti-oxidant, surface active agent, coating material, etc. its process is first prepared vitamin into farine with fineness above 150 mesh. Take base material of formula and soluble after heating, adding vitamin farine and relevant auxiliary material, mixing into even dispersible solution, dropping into condenser and becoming pills, preparing into pills with coating or non-coating. Each pill containing vitamin 0.05mg-30mg and its weight is 10mg-100mg.

Description

technical field [0001] The invention relates to vitamin dripping pills and a preparation method thereof, belonging to the technical field of medicine preparation. Background technique [0002] Human understanding of vitamins began more than 3,000 years ago. At that time, the ancient Egyptians discovered that night blindness could be cured by some foods, although they did not know what substances in the foods played a medical role. This is the most obscure human understanding of vitamins. In 1912, Polish scientist Fonke extracted a white substance from rice bran that could treat beriberi. This material is called " life-sustaining nutrient " by funk, is called for short Vitamin (vitamin), also claims vitamin. After that, researchers from all over the world conducted extensive research on the medical effects of vitamins and found that vitamins have more and more medical effects. Long-term studies have confirmed that vitamins are indispensable nutrients for the human body. I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/714A61K31/525A61K31/519A61K31/455A61K31/4415A61K31/197A61P3/02A61K31/51A61K31/4188A61K31/375A61K31/355A61K31/352A61K31/59A61K31/122
Inventor 庄洪波
Owner AOLING BODA MEDICINE SCI & TECH DEV BEIJING
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