Measurement of EEG Reactivity

a reactivity and eeg technology, applied in the field of eeg reactivity measurement, can solve the problems of patient inability to respond, inapplicability of observational scoring system, and disturbed brain function and resulting eeg

Active Publication Date: 2008-08-14
GENERAL ELECTRIC CO
View PDF7 Cites 33 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0014]The present invention seeks to provide an automated reactivity test that provides a

Problems solved by technology

Different derangements of internal system homeostasis disturb the environment in which the brain operates, and therefore the function of the brain and the resulting EEG are disturbed.
Moreover, the test of EEG reactivity provides information regarding the state of a patient for whom the GCS or another observational scoring system is not applicable.
This is the case, for example, when neuromuscular blocking agents have been administered to the patient, which makes the patient unable to respond and thu

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Measurement of EEG Reactivity
  • Measurement of EEG Reactivity
  • Measurement of EEG Reactivity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037]As discussed above, the present invention rests on adaptive segmentation of the physiological signal for detecting changes in the stationarity of the signal. In adaptive segmentation, the signal is not processed in fixed length time windows termed epochs, as is common in EEG analysis, but rather on a sample-by-sample basis.

[0038]FIG. 1 illustrates one embodiment of the present invention. An EEG signal measured from a patient (step 10) is first digitized to obtain a time series of EEG signal data. The sampled EEG signal may then be filtered to exclude high- and low-frequency artifacts (step 11). The signal data obtained initially from the patient may also be termed reference signal data in this context, since it is employed at step 12 to construct a valid signal model for the current time series. The signal model constructed enables prediction of signal values for the time series and a valid signal model meets predetermined criteria in the prediction. For example, the signal mo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a method and apparatus for assessing the reactivity observable in a certain physiological signal, especially the EEG signal, of a comatose subject. In order to obtain an objective and a reliable measure of the reactivity automatically and without the presence of a trained EEG specialist, a valid signal model is constructed for an EEG signal obtained from the subject. A time reference corresponding to a stimulus is applied and further signal data is obtained from the time series, the further signal data being subsequent to the time reference. By employing the further signal data, the method tests whether the signal model remains to be a valid signal model for the EEG signal also after the stimulus, and indicates, based on the test, whether reactivity is present in the physiological signal.

Description

FIELD OF THE INVENTION[0001]The present invention relates to the assessment of the reactivity of the central nervous system of a patient to external stimulation as observable on / in a physiological signal, especially an EEG signal. Below, the reactivity observable on / in a physiological signal is termed physiological signal reactivity. If the physiological signal concerned is an EEG signal, the said reactivity is termed briefly EEG reactivity.BACKGROUND OF THE INVENTION[0002]Neuromonitoring is a subfield of clinical patient monitoring focused on measuring various aspects of brain function and on changes therein caused by neurological diseases, accidents, and drugs commonly used to induce and maintain anesthesia in an operation room or sedation in patients under critical or intensive care.[0003]Electroencephalography (EEG) is a well-established method for assessing brain activity. When measurement electrodes are attached on the skin of the skull surface, the weak biopotential signals g...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61B5/0476
CPCA61B5/0484A61B5/7221A61B5/7203G06F19/322A61B5/377G16H10/60
Inventor SARKELA, MIKAVIRTANEN, JUHAVIERTIO-OJA, HANNA E.SALMI, TAPANI
Owner GENERAL ELECTRIC CO
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap