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45 results about "Chronic infectious disease" patented technology
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An infectious disease is caused by bacteria, viruses, etc. A chronic disease is anything that lasts for a long time. You could have a chronic infection, which would be a germ that lasts for a long time. Infectious diseases are caused by germs, microbes, viruses, etc, and can be passed from one person to the other.
Construction method of digital human health management system for chronic infectious diseases
The application discloses a kind of chronic infectious disease digital people health management system construction method, it relates to AIDS nursing management technical field.Based on Triangle model, the management classification and characteristics of HIV patients are determined by latent profile and association rule analysis, and it is embedded into applet using agile development;Based on the basic nursing framework, the commonality and difference of patients in different levels are explored Care needs;Through the preliminary construction of AIDS hierarchical case management program by range review and focus group interview, the final draft is formed by revising and improving through written evaluation and field demonstration, and the well-constructed management program is embedded into a digital human interaction platform based on artificial intelligence.The application protects the privacy of patients, alleviates the shortage of medical human resources, meets the growing health needs of HIV patients, improves patient satisfaction and improves the quality of HIV care services.
Owner:SHANGHAI PUBLIC HEALTH CLINICAL CENT
Anti-PD-L1 nano antibody and application thereof
PendingCN121758619Ahigh affinityStrong specificityImmunoglobulins against cell receptors/antigens/surface-determinantsX-ray constrast preparationsImmunologic disordersAutoimmune condition
The invention belongs to the technical field of biological medicine, and discloses an anti-PD-L1 nano antibody and application thereof. And the amino acid sequences of CDR1-3 of the PD-L1 nano antibody are respectively shown as SEQ ID NO.2-4. The PD-L1 nano antibody is a PD-L1 antibody. The nano antibody can effectively block the combination of PD1 and PDL1, is high in affinity and strong in specificity, can be used for immunoblotting, enzyme-linked immunosorbent assay kits and flow cytometry counting, can also be used for treating diseases such as tumors, autoimmune diseases and chronic infectious diseases, and has the potential of being developed as an immune checkpoint inhibitor.
Owner:GUANGZHOU FINELMMUNE BIOTECHNOLOGY CO LTD
Metal-organic framework for inhibiting m2 macrophage activity, and pharmaceutical composition comprising same
PCT designated stageWO2026071545A1Heavy metal active ingredientsMetabolism disorderTissue remodelingInfective disorder
The present invention relates to a metal-organic framework for inhibiting the activity of M2 macrophages, and a pharmaceutical composition comprising same, wherein the metal-organic framework of the present invention is non-toxic to cells and can exhibit an effect of inhibiting the activity of M2 macrophages. More specifically, the metal-organic framework of the present invention can be provided as an anticancer composition for tumor-related macrophage-mediated diseases, particularly solid cancer, through the inhibition of M2 macrophages capable of increasing the expression of genes associated with parasite invasion, tissue remodeling, and tumor proliferation (immunomodulatory function), and can also be provided as a pharmaceutical composition for treating chronic infectious diseases, liver cirrhosis, obesity-related metabolic diseases, scar formation and idiopathic lung diseases.
Owner:MEDIARK INC