Hydrophobia split vaccine for human body

Abstract

The invention discloses a hydrophobia cracking vaccine and preparing method, which comprises the following steps: fixing toxic plant seeded cell, culturing, obtaining virus liquid, cracking the hydrophobia virus particle through chemical method, extracting, condensing, purifying hydrophobia film segment with barb protrusion and base protein, allocating further to obtain the product.

Description

technical field

[0001] The invention relates to a rabies split vaccine. Specifically, the present invention relates to a rabies whole virus particle harvested after cell culture is chemically lysed, and the virus envelope (Envelope) fragment containing spike (G glycoprotein spike) and matrix protein (Matrix protein) is extracted, Reconstituted into a rabies split virus vaccine (Rabies split virus vaccine). This split virus vaccine is used to prevent rabies in humans caused by rabies virus infection. The invention also relates to the preparation method of the virus split vaccine. Background of the invention

[0002] Rabies is an acute infectious disease caused by rabies virus infection, and is a zoonotic acute infectious disease with natural foci. Rabies virus infects humans mainly through skin wounds and mucous membranes. The incubation period of rabies can range from several days to several years, with an average of 20 to 90 days. The crowd is generally susceptible. In...