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Chinese medicine composition and its suppository and application

A composition and technology of traditional Chinese medicine, applied in the field of application in the preparation of drugs for detoxification and anti-addiction

Active Publication Date: 2009-12-02
浙江中医学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is no report on clinical application

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  • Chinese medicine composition and its suppository and application
  • Chinese medicine composition and its suppository and application
  • Chinese medicine composition and its suppository and application

Examples

Experimental program
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Effect test

Embodiment 1

[0048] Embodiment 1: preparation of iced tea suppository

[0049] Prescription: 150.2kg of tea leaves, 60.2kg of cassia twigs, 40g of freeze-dried Agkistrodon halys, 600g of borneol;

[0050] Preparation method: add 4.5kg of lime milk to the tea leaves, add 240kg of water and mix evenly, after the tea leaves are soaked, add 1500kg of water, heat with steam to 40°C-50°C, keep for 1 hour, filter to obtain 950kg of filtrate. The filtrate was concentrated to a relative density of 1.06 (80° C.), poured into a crystallization tank, controlled the crystallization temperature to 40° C., separated the crystals, and dried in vacuum to obtain 1.33 kg of tea extract powder. The extraction rate was 0.88%. Chopped cassia twigs, added to the still, added 1200kg of water, soaked for 2 hours, heated to boiling, and kept for 4 hours, collected the distillate, allowed to stand for stratification, and took the upper layer of oil to obtain 26mL. The extraction rate was 0.43%. The distilled aqueo...

Embodiment 2

[0051] Embodiment 2: preparation of iced tea suppository

[0052] Prescription: 135.5kg of tea leaves, 54.2kg of cassia twigs, 36g of freeze-dried Agkistrodon halys, 540g of borneol;

[0053] Preparation method: add 4.1kg of lime milk to the tea leaves, add 217kg of water and mix evenly, after the tea leaves are soaked, add 1350kg of water, heat with steam to 40°C-50°C, keep for 1 hour, filter to obtain 840kg of filtrate. The filtrate was concentrated to a relative density of 1.06 (80°C), poured into a crystallization tank, controlled the crystallization temperature to 40°C, separated the crystals, and dried in vacuum to obtain 1.22kg of tea extract powder. The extraction rate was 0.9%. Chopped cassia twigs, added to the still, added 1100kg of water, soaked for 2 hours, heated to boiling, and kept for 4 hours, collected the distillate, allowed to stand for stratification, and took the upper layer of oil to obtain 24mL. The extraction rate was 0.45%. The distilled aqueous sol...

Embodiment 3

[0054] Embodiment 3: preparation of iced tea suppository

[0055] Prescription: 165.0kg of tea leaves, 66.5kg of cassia twigs, 44g of freeze-dried Agkistrodon halys, 650g of borneol;

[0056]Preparation method: add 5.0kg of lime milk to the tea leaves, add 260kg of water and mix evenly, after the tea leaves are soaked, add 1650kg of water, heat to 40°C-50°C with steam, keep for 1 hour, filter to obtain 1050kg of filtrate. The filtrate was concentrated to a relative density of 1.06 (80° C.), poured into a crystallization tank, controlled the crystallization temperature to 40° C., separated the crystals, and dried in vacuum to obtain 1.51 kg of tea extract powder. The extraction rate was 0.92%. Chopped cassia twigs, added to the still, added 1300kg of water, soaked for 2 hours, heated to boiling, and kept for 4 hours, collected the distillate, allowed to stand for stratification, and took the upper layer of oil to obtain 29mL. The extraction rate was 0.44%. The distilled aqueo...

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Abstract

The present invention provides one kind of Chinese medicine composition, and its suppository and application in preparing opioid drug-relieving medicine and, especially, opioid analgesic. The Chinese medicine composition contains the main active components including tea, cassia twig, borneol and freeze dried snake venom of Agkistrodon halys Pallas. The Chinese medicine composition and its suppository is superior to commonly used Western non-opium excitant, and has fast detoxification, high safety, no toxic side effect and no addiction, and is suitable for use in household.

Description

(1) Technical field [0001] The invention relates to a traditional Chinese medicine composition for detoxification and anti-addiction, a suppository of the Chinese medicine composition, and an application of the traditional Chinese medicine composition in preparing medicine for detoxification and anti-addiction. (2) Background technology [0002] Drug abuse is one of the global social problems today. The traditional alternative and step-down therapy of Western medicine still has the problems of drug dependence and high relapse rate to varying degrees. In order to give full play to the role of traditional Chinese medicine, it is of great significance to find and study effective and safe methods and preparations of Chinese medicine detoxification, to suppress the withdrawal symptoms of drug addicts, and to make drug addicts quickly withdraw from addiction. [0003] Drug addiction is medically known as "opioid dependence". This is a medical and sociological problem that has pla...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61K36/54A61K35/58A61K31/045A61K9/02A61P25/36A61P25/04A61K35/583
Inventor 王泽时
Owner 浙江中医学院
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