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1 results about "Agkistrodon halys" patented technology

Characteristic polypeptides of the golden-flowered snake and their applications

This invention pertains to the field of *Snakehead sinensis*, specifically relating to its characteristic polypeptides and their applications. Specifically, it covers the characteristic polypeptides of *Snakehead sinensis*, a mass spectrometry-based method for authenticity identification, and the application of these characteristic polypeptides in the preparation of drugs for treating rheumatoid arthritis. This invention provides a characteristic polypeptide, QDVDNASLVR, which is found only in *Snakehead sinensis* and can be stably detected. Its amino acid sequence is not reported in the literature, making it a novel polypeptide. An LC-MRM-MS method for authenticity identification based on this characteristic polypeptide is established, achieving accurate differentiation from *Snakehead rubrum* and *Agkistrodon halys*, with a 100% authenticity identification rate. This invention also provides a characteristic polypeptide, SFLGVPFAK, with anti-rheumatoid arthritis activity. Its amino acid sequence is not reported in the literature, making it a novel polypeptide. Its target and pathway can be predicted, or it can be applied to the modification of anti-rheumatoid arthritis active polypeptides.
Owner:JINAN UNIVERSITY