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Vitamin C injection and preparation method thereof

A technology of water for injection and vitamins, applied in the field of water for injection needles, which can solve the problems of long production process and high product cost

Active Publication Date: 2008-06-25
魏锐 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this solid preparation has the disadvantages of long production process and high product cost. Therefore, if a preparation with low cost and good stability is obtained, it has always been a problem that those skilled in the art have been working hard to solve.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] prescription:

[0024] Sodium vitamin C (calculated as vitamin C) 3000g

[0025] Sodium metabisulfite 20g

[0026] L-cysteine ​​hydrochloride 10g

[0027] Edetate Disodium 3g

[0028] Add water for injection to 10000ml

[0029]

[0030] Makes 1000 bottles

[0031] Production Process:

[0032] 1. Preparation of liquid medicine:

[0033] Take sodium metabisulfite, L-cysteine ​​hydrochloride, and disodium edetate, add them to 60% volume water for injection prefilled with carbon dioxide, stir to dissolve, add vitamin C sodium according to the prescription amount, stir to dissolve, measure pH value.

[0034] 2. Depyrogenation:

[0035] Add 0.1% activated carbon to the liquid medicine, stir and absorb for 30 minutes, filter, add water for injection prefilled with carbon dioxide to the full amount, and check.

[0036] 3. Packing and packing:

[00...

Embodiment 2

[0039] prescription:

[0040] Sodium vitamin C (calculated as vitamin C) 1000g

[0041] Sodium sulfite 6g

[0042] L-cysteine ​​hydrochloride 3g

[0043] Edetate Disodium 1g

[0044] Add water for injection to 2000ml

[0045]

[0046] Makes 1000 bottles

[0047] The production process is the same as in Example 1, except that the amount of activated carbon added is 0.5%, and the stirring time is 60 minutes.

Embodiment 3

[0049] prescription:

[0050] Sodium vitamin C (calculated as vitamin C) 1000g

[0051] Sodium Metabisulfite 3g

[0052] L-cysteine ​​6g

[0053] Edetate Disodium 0.1g

[0054]Add water for injection to 2000ml

[0055]

[0056] Makes 1000 bottles

[0057] Production technology is with embodiment 1.

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PUM

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Abstract

The invention discloses a vitamin C sodium squirt cut for injection and a preparation method, and the invention belongs to the field of the medical industry, and the invention relates to a vitamin squirt cut for injection and a preparation method, in particular discloses a vitamin C sodium squirt cut. The vitamin C sodium squirt cut comprises the vitamin C sodium, the anti-oxidant, the anti-oxygen synergistic agent and the water for the injection. The preparation method comprises three procedures which are the preparing of liquid medicine, the removing of the origin of heat and the split charging. Compared with the listed vitamin C sodium preparations, the vitamin C sodium squirt cut has the advantages of low cost and good stability, and the invention can be widely applied in the field of the medical industry.

Description

technical field [0001] The invention relates to a water needle for injection, and more specifically, the invention discloses a water needle for injection of vitamins and a preparation method thereof. Background technique [0002] Vitamin C, also known as ascorbic acid, is a water-soluble vitamin. The main function of vitamin C in the human body is to participate in the metabolism of amino acids, the synthesis of neurotransmitters, the synthesis of collagen and tissue interstitium, reduce the permeability of capillaries, accelerate blood coagulation, stimulate blood coagulation, and promote iron Absorbed in the intestines, it promotes the reduction of blood lipids, increases the resistance to infection, participates in detoxification, and has the effect of antihistamine and preventing the formation of carcinogens (nitrosamines). [0003] The enol chemical structure of vitamin C makes it extremely unstable, easy to oxidize and change color when exposed to air, stable in acidi...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/375
Inventor 魏锐程琪
Owner 魏锐
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