32 results about "VITAMIN C INJECTION" patented technology

The invention discloses a mesenchymal stem cell self-preserving liquid which is prepared from the following raw materials according to volume ratios: 1-6% of self platelet lysate, 95-97% of solution medium and 0-1% of vitamin C injection, wherein the solution medium is a mixed sugar electrolyte injection or physiological saline injection. The mesenchymal stem cell self-preserving liquid has the advantages that: growth factors contained in the mesenchymal stem cell self-preserving liquid can maintain the activity state of cells, the vitamin C can maintain the activity of various peroxidases, at the same time, the mixed sugar electrolyte injection is especially suitable for cell preservation, and osmotic pressure is also favorable for nutrient absorption of the cells so as to carry out metabolism; the activity of the mesenchymal stem cells which are preserved in the mesenchymal stem cell self-preserving liquid within 8 hours is still larger than 90%, the cell activity change is not larger than 7%, and the activity of the mesenchymal stem cells which are preserved in the mesenchymal stem cell self-preserving liquid within 12 hours is still maintained at 85%; and by using the mesenchymal stem cell self-preserving liquid, the requirements for human intravenous back-transfusion safety can be met, and the cell preserving problem of long-time transport is solved, thus more patients have opportunity to undergo mesenchymal stem cell treatment.

The invention relates to a vitamin C injection and a preparation method thereof. An antioxidant, a metal chelating agent, and 20-26% of sodium bicarbonate for adjusting the pH to 5-7 are added to prevent preparation oxidation. The vitamin C injection prepared through adopting the method disclosed by the present invention has a good stability.

The invention discloses a medical composition for injection, which is characterized by comprising the following components by weight part: 5-20 parts of vitamin B1, 1-10 parts of riboflavin sodium phosphate (metered by riboflavin), 100-300 parts of vitamin C, 100-500 parts of excipient, 0.1-1 part of complexing agent and a pH regulating agent. Compared with a vitamin C injection on the market, the medical composition has low content of related substances and high content of effective constituents; and proved by high-temperature, high-humidity and strong-light tests, the medical composition has better stability.

The invention discloses a cryopreserving solution for clinical-grade CAR-T cryopreservation and capable of being directly reinfused through intravenous infusion. The cryopreserving solution comprisesthe following raw materials: dimethyl sulfoxide, a glycerol fructose sodium chloride injection, an invert sugar electrolyte injection, a dextran 40 glucose injection, a hydroxyethyl starch 130/0.4 electrolyte injection, a vitamin C injection, a human serum albumin injection and a 0.9 % sodium chloride injection; the cryopreserving solution has the pH value of 6.8-7.0. When a formula for the clinical-grade CAR-T cryopreservation and capable of being directly reinfused through the intravenous infusion is used for cryopreserving CAR-T cells, the thawed cells and the thawed cryopreserving solutiondo not need centrifugation, resuspension, fluid exchange and other processes and can be directly reinfused through the intravenous infusion, so that the loss of cell varieties due to pollution in-vitro repeated proliferation of the CAR-T cells, or changes of cell morphologies and cell functions are effectively avoided, medical equipment can be also significantly simplified and the workload of medical workers can be reduced.

The invention relates to the technical field of cryopreservation solutions, in particular to a cryopreservation solution for long-term preservation of human umbilical cord mesenchymal stem cells. The cryopreservation solution for long-term preservation of the human umbilical cord mesenchymal stem cells at least comprises the following preparation raw materials: dimethyl sulfoxide, human serum albumin, a compound electrolyte injection, a sodium chloride injection, a trehalose solution, dextran and a vitamin C injection. The cryopreservation liquid has small toxic and side effects on the human umbilical cord mesenchymal stem cells, can be directly used clinically, obviously improves the safety and biocompatibility of human umbilical cord mesenchymal stem cell retransfusion to human bodies, can improve the motility, proliferation and differentiation capabilities of the human umbilical cord mesenchymal stem cells on the premise of reducing the use amount of DMSO (dimethylsulfoxide), and can be directly retransfused after resuscitation, centrifugal washing is not needed, and damage to cells is reduced.

The invention discloses a vitamin C sodium squirt cut for injection and a preparation method, and the invention belongs to the field of the medical industry, and the invention relates to a vitamin squirt cut for injection and a preparation method, in particular discloses a vitamin C sodium squirt cut. The vitamin C sodium squirt cut comprises the vitamin C sodium, the anti-oxidant, the anti-oxygen synergistic agent and the water for the injection. The preparation method comprises three procedures which are the preparing of liquid medicine, the removing of the origin of heat and the split charging. Compared with the listed vitamin C sodium preparations, the vitamin C sodium squirt cut has the advantages of low cost and good stability, and the invention can be widely applied in the field of the medical industry.

The invention discloses a fruit and vegetable VC nutrition lotion and a preparation method thereof. The lotion is prepared from, by weight, 50-70 parts of vitamin C injection, 3-7 parts of rose stamens, 3-7 parts of Hangzhou chrysanthemum flowers, 6-10 parts of cucumbers, 5-9 parts of green peppers, 4-8 parts of tomatoes and 7-11 parts of strawberries. The preparation method comprises the steps that the vitamin C injection is poured into a vessel, other cleaned raw materials are put into the vessel, soaking is conducted for 10 h to 15 h at room temperature, filtering and bottling are conducted, and the lotion is obtained. The fruit and vegetable VC nutrition lotion has the effects of reliving itching, moisturizing skin, whitening the skin, achieving moisturizing and promoting skin metabolism and has multiple effects of fading spots, removing acne, enhancing skin elasticity, removing skin toxin, activating the skin and the like, when the lotion is used, the lotion can rapidly penetrate the skin, toxic and side effects and irritation are not generated to the human skin, and the lotion is safe and reliable.

The invention discloses a vitamin C injection and a preparation method thereof. The vitamin C injection is prepared from the following components by weight: 5.000kg of vitamin C, 2.498-2.502kg of sodium bicarbonate, 39.970-40.020g of sodium metabisulfite, 39.980-40.020g of L-cysteine hydrochloride, 39.980-40.010g of sodium hydrosulfite, 29.990-30.020g of thioglycerol, 9.990-10.010g of sodium calcium edentate, 59.960-60.010g of activated carbon for 767 type injections and water for injection which is added until the volume of the mixture is 20L. The invention further discloses a preparation method of the vitamin C injection. The novel formula of combination of four antioxidants sodium metabisulfite, L-cysteine hydrochloride, sodium hydrosulfite and thioglycerol is adopted, so that the oxidation resistance of vitamin C is effectively improved, the impurity content is reduced, and the product appearance is changed from a general light yellow clear liquid into a transparent clear liquid.

The invention discloses vitamin C injection and a preparation method thereof. The preparation method comprises the following steps: 1) introducing CO2 into water for injection until the concentrationof the CO2 is 1.2 to 1.449 g/L, so as to prepare a solvent; 2) adding disodium ethylenediaminetetraacetate and vitamin C into the solvent prepared in step 1) and mixing to prepare a first solution; 3)adding sodium bicarbonate and sodium hydrogen sulfite into the first solution; regulating the pH (Potential of Hydrogen) to be 5.9 to 6.2 to prepare a second solution; 4) adding activated carbon intothe second solution and mixing; then decarbonizing to prepare a third solution; 5) carrying out rough filtering and fine filtering on the third solution in sequence to prepare the vitamin C injection, wherein the pore diameter of a filter membrane in the rough filtering process is 0.4 to 0.6 mum and the pore diameter of a filter membrane in the fine filtering process is 0.1 to 0.3 mum. By adopting the preparation method provided by the invention, the oxidization degree of the vitamin C injection can be effectively lowered and the quality and preservation time of the vitamin C injection are improved; the problems that medicine liquid becomes yellow and the like are avoided.

The invention discloses a sodium selenite and vitamin C injection. The injection is prepared from raw materials and auxiliary materials and is characterized in that the raw materials comprise, by weight, 1 g of sodium selenite and 50 g of vitamin C; the auxiliary materials comprise, by weight, 50 ml of ethanol, 100 ml of polysorbate-80 and 1,000 ml of water for injection. The sodium selenite and vitamin C injection and the preparation method thereof have the characteristics that the production efficiency is high, the injection can supplement domestic animals with selenium and vitamin C and isconvenient to use and the like.

The invention discloses a preservation method of a mesenchymal stem cell. The method comprises freezing preservation liquid. A preparation method of the freezing preservation liquid comprises the steps of dissolving dimethyl sulfoxide, sodium citrate and citric acid in a solution medium, adding a vitamin C injection into the solution medium, adding human plasma and human serum albumin, and at last, adding low molecular weight calcium heparin to form the required freezing preservation liquid. The invention aims at providing the preservation method of the mesenchymal stem cell with a higher survival rate and a higher growth rate after thawing.

The present invention discloses a Qianliexian Weisuokangyan injection for effectively curing hyperplasia of prostate and prostatic hypertrophy with chronic prostatitis. It is made up by mixing 25% (g.wt/100ml) sorbitol injection 4 ml, 10% vitamin C injection 2 ml, 1% L-ofloxacin injection 2 ml and 2% lidocaine injection 2 ml.

The invention relates to the technical field of vitamin C injections, and specifically provides a control method for anti-oxidation of a vitamin C injection. The method comprises the following steps:(1) quality control of the raw material medicine vitamin C and auxiliary materials; (2) cleaning and drying of ampoule bottles; (3) preparation: the raw material vitamin C and auxiliary materials areadded according to the prescription dosage to prepare a liquid medicine; (4) fine filtration: filtration is performed through a 0.22 micron microporous membrane cartridge filter; (5) potting; (6) sterilization: the sterilization condition is 100 DEG C and 9 min. After sterilization, spray equipment is turned on to cool the ampoule bottles. The raw material is strictly controlled, and the process is adjusted and optimized. After the vitamin C injection produced by the above control method is detected through an acceleration test and a long-term stability test, various properties all meet the standard requirements, stability of the product is improved, and production efficiency of the optimized process and qualified rate of the finished product are both obviously improved.

The invention discloses a sodium selenite vitamin C injection and a preparation method thereof. The preparation method comprises the steps that edetate disodium, sodium metabisulfite and seleninic acid are sequentially added into injection water saturated by carbon dioxide, vitamin C is added after the materials are completely dissolved, stirring is conducted so that the vitamin C is completely dissolved, then sodium bicarbonate is added, and the injection water is added finally to get constant volume, so that a mixed solution is obtained; medicinal active carbon is added into the mixed solution, the mixed solution is stirred and filtered to be decarburized, and a filtered filtrate is subjected to refined filtration by using an ultrafiltration membrane; and carbon dioxide gas is continuously guided into the filtrate which is subjected to refined filtration, and a product is potted, sealed and sterilized under existence of carbon dioxide, so that the injection is obtained. The production technology of the preparation method is simple and easy to control; the production efficiency is high by adopting the preparation method, effective components in the injection are stable, and the injection is very suitable for supplementing selenium and vitamin C to domestic animals, and has high popularization and application value.

The invention relates to an injection medicament, in particular to a medicament for emasculating sows. The medicament for emasculating the sows is characterized by comprising the following raw materials: medroxyprogesterone acetate, vitamin C injection, vitamin B12 injection and cleaning agent. Thus, the medicament has the advantages of high emasculation applicability, stress reduction, no infection, no mortality rate, obvious emasculation effect, low dosage and low cost, and can increase the economic benefits of sow raisers. Compared with the traditional surgical emasculation method, the medicament can save more time and labor and increase the rate of liveweight growth. Besides, the pork from the slaughtered sow has fresh color and good taste, and the mouth feel of the pork is not reduced.

The invention discloses high-glucose eye drops. The high-glucose eye drops are prepared from the following raw materials in parts by weight: 0.1 to 0.2 part of taurine, 30 to 50 parts of 50 percent ofa glucose injection, 0.3 to 0.6 part of a vitamin C injection, 0.0002 to 0.0006 part of a vitamin B12 injection and 0.04 to 0.1 part of an antibacterial stabilizer. By introducing the antibacterial stabilizer into the high-glucose eye drops disclosed by the invention, the eye drops are endowed with a better antibacterial effect; in addition, the preservative performance of a product is improved and the storage period of the eye drops is prolonged; the high-glucose eye drops can be produced in batches and are prepared into bottled products; patients from major hospitals can share the product,so the product can bring good treatment and prognosis to more patients.

The invention provides a drug formula used for promoting skin wound healing, which belongs to the field of a drug formula. The formula is characterized in that the formula includes, by weight, 40-60 parts of a vitamin C injection (5 ml:1 g), 10-20 parts of a vitamin B1 injection (1 ml:50 mg), 10-20 parts of a vitamin B6 injection (1 ml:50 mg), and 10-20 parts of a raceanisodamine hydrochloride injection (1 ml:10 mg). The drug formula is mainly used for treatment of diabetic foot and bedsore, and has good effects of being resistant to inflammation, relieving pain, controlling infection and ulceration, improving microcirculation, and promoting wound healing.

The invention discloses a combination drug for treatment of piglet edema disease. The combination drug comprises Rumex crispus extract solution, glucose injection, kanamycin sulfate injection, dexamethasone injection and vitamin C injection. Rumex crispus extract is used herein as a main material assisted by the solutions, such as glucose injection, kanamycin sulfate injection, dexamethasone injection and vitamin C injection; tests show that the combination drug is more effective in treating piglet edema disease than traditional drugs.

The invention relates to a method for preparing a technetium (99mTc) methylene diphosphonate injection medicament with long effective period. The method specifically comprises the following steps: diluting a vitamin C injection by 20-200 times according to the requirements; pumping 10-200mCi of high-technetium (99mTc) acid sodium injection and diluting to 4ml; taking a stannous methylene diphosphonate lyophilized product for injection out of a refrigerator and placing into room temperature; injecting the high-technetium (99mTc) acid sodium injection into the stannous methylene diphosphonate lyophilized product once, shaking, fully dissolving, standing for 5min and obtaining the technetium (99mTc) methylene diphosphonate injection; and pumping 0.1ml of the well diluted vitamin C injection by using a disposable sterile syringe, injecting into the well prepared technetium (99mTc) methylene diphosphonate injection and uniformly shaking. Compared with the prior art, the prepared technetium (99mTc) methylene diphosphonate injection medicament has the advantages of long effective period, no decomposition in transportation process, relatively good imaging effect and the like.