Medical composition of compound vitamin C injection

A compound vitamin and vitamin technology, applied in the field of medicine, can solve the problems of poor stability of vitamin C and the like

Inactive Publication Date: 2010-01-13
北京普瑞博思生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the improvement of people's living standards, the clinical application of total parenteral nutrition is becoming more and more extensive, and the market potential is huge. Compound vitamin C injection has been on the market in Japan for several years, but vitamin C has poor stability in aqueous solution. Therefore, pharmaceutical developers hope to develop Stabilized Vitamin C Compound Injection

Method used

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  • Medical composition of compound vitamin C injection
  • Medical composition of compound vitamin C injection
  • Medical composition of compound vitamin C injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A compound vitamin C injection pharmaceutical composition, the raw material is vitamin B 1 5g, riboflavin sodium phosphate (calculated as riboflavin) 1g, vitamin C 100g, vitamin C and cation exchange resin mixed to obtain vitamin C sodium, and vitamin B 1 , Riboflavin sodium phosphate is prepared as an injection.

Embodiment 2

[0046] A compound vitamin C injection pharmaceutical composition, the raw material is vitamin B 1 20g, riboflavin sodium phosphate (calculated as riboflavin) 10g, vitamin C 300g, vitamin C is mixed with cation exchange resin to obtain vitamin C sodium, and vitamin B 1 , Riboflavin sodium phosphate is prepared as an injection.

Embodiment 3

[0048] A compound vitamin C injection pharmaceutical composition, the raw material is vitamin B 1 6g, riboflavin sodium phosphate (calculated as riboflavin) 2g, vitamin C 120g, vitamin C is mixed with cation exchange resin to obtain vitamin C sodium, and vitamin B 1 , Riboflavin sodium phosphate is prepared as an injection.

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PUM

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Abstract

The invention discloses a medical composition of a compound vitamin C injection, which comprises the following raw materials by weight part: 5-20 parts of vitamin B1, 1-10 parts of riboflavin sodium phosphate (metered by riboflavin) and 100-300 parts of vitamin C. The medical composition is characterized in that the vitamin C is mixed with cation exchange resin to obtain vitamin C sodium, and the vitamin C sodium, the vitamin B1 and the riboflavin sodium phosphate are prepared into an injection. Compared with a compound vitamin C injection on the market, medical composition has less reduction of effective constituents such as the vitamin C, and the like in a preparation process and has low content of related substances and high content of the effective constituents. Proved by high-temperature, high-humidity and strong-light tests, the compound vitamin C injection has better stability.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to a compound vitamin C injection pharmaceutical composition. Background technique [0002] The so-called "nutrition supplement" includes five essential nutrients for the body, such as sugars, proteins, fats, vitamins, and minerals. These substances bypass the liver and enter the systemic circulation directly. The assimilation rate may be slightly lower than that of food intake through the gastrointestinal tract. It can meet the needs of maintaining nutrition and provide nutrients outside the stomach and intestines to reduce secretion and peristalsis of the digestive tract, so that the digestive tract is at rest, which is conducive to disease recovery or healing. Sometimes, although it is not possible to achieve complete self-healing, after active nutritional support, the overall condition has been greatly improved, which greatly increases the chances of success in further treatment and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/525A61K31/51A61K31/375A61K9/08A61J3/00A61P3/02
Inventor 郭鸿旭谢小飞张艳清
Owner 北京普瑞博思生物科技有限公司
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