High-glucose eye drops

A technology of eye drops and high sugar, which is applied in the field of medicine, can solve the problems of single function of high sugar eye drops, can only use 1-2 drops, and is easy to breed bacteria, so as to improve anti-corruption and use safety Good, good antibacterial effect

Inactive Publication Date: 2018-11-06
THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For this reason, ophthalmology often adopts the "high-sugar eye drops" that are currently configured and drips them into the affected eye to treat corneal edema or nourish the cornea; It can only be prepared and used immediately. This kind of patients generally need eye drops 6 times / day or 1 time / hour. At the same time, the current high-sugar eye drops have relatively single functionality; therefore, how to produce eye drops that can be maintained for a long time and have strong functionality is the focus of current research

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The high-sugar eye drops of the present embodiment, it is made up of the raw material of following weight portion:

[0022] Taurine 0.2, 50% glucose injection 50, vitamin C injection 0.6, vitamin B12 injection 0.0006 and antibacterial stabilizer 0.1.

[0023] Described antibacterial stabilizer is made up of the raw material of following weight part:

[0024] Coptidis 20, honeysuckle 7, chamomile 13, polysorbate 2, Houttuynia cordata 4, chelating agent 0.02, L-ascorbic acid 0.5, osmotic pressure regulator 2 and calcium chloride 0.1.

[0025] The osmotic pressure regulator is propylene glycol.

[0026] Described chelating agent is ethylenediaminetetraacetic acid.

[0027] The preparation method of described antibacterial stabilizer comprises the following steps:

[0028] (1) Mix Coptidis rhizome, honeysuckle, and chamomile, add it to 40% ethanol solution that is 30 times the weight of the mixture, heat and stir at 65°C for 2 hours, filter to obtain the alcohol extract;...

Embodiment 2

[0037] The high-sugar eye drops of the present embodiment, it is made up of the raw material of following weight portion:

[0038] Taurine 0.15, 50% glucose injection 40, vitamin C injection 0.5, vitamin B12 injection 0.0002 and antibacterial stabilizer 0.04.

[0039] Described antibacterial stabilizer is made up of the raw material of following weight part:

[0040] Coptidis 15, honeysuckle 5, chamomile 12, polysorbate 1.5, Houttuynia cordata 3.5, chelating agent 0.015, L-ascorbic acid 0.4, osmotic pressure regulator 1.5 and calcium chloride 0.009.

[0041] The osmotic pressure regulator is propylene glycol.

[0042] Described chelating agent is ethylenediaminetetraacetic acid.

[0043] The preparation method of described antibacterial stabilizer comprises the following steps:

[0044] (1) Mix Coptidis rhizome, honeysuckle and chamomile, add to 35% ethanol solution 20 times the weight of the mixture, heat and stir at 60°C for 1 hour, filter to obtain alcohol extract;

[0...

Embodiment 3

[0053] The high-sugar eye drops of the present embodiment, it is made up of the raw material of following weight portion:

[0054] Taurine 0.1, 50% glucose injection 30, vitamin C injection 0.3, vitamin B12 injection 0.0002 and antibacterial stabilizer 0.04.

[0055] Described antibacterial stabilizer is made up of the raw material of following weight part:

[0056] Coptidis 10, honeysuckle 4, chamomile 10, polysorbate 1, houttuynia 3, chelating agent 0.01, L-ascorbic acid 0.3, osmotic pressure regulator 1 and calcium chloride 0.008.

[0057] The osmotic pressure regulator is propylene glycol.

[0058] Described chelating agent is ethylenediaminetetraacetic acid.

[0059] The preparation method of described antibacterial stabilizer comprises the following steps:

[0060] (1) Mix Coptidis rhizome, honeysuckle and chamomile, add to 35% ethanol solution 20 times the weight of the mixture, heat and stir at 60°C for 1 hour, filter to obtain alcohol extract;

[0061] (2) Take Ho...

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PUM

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Abstract

The invention discloses high-glucose eye drops. The high-glucose eye drops are prepared from the following raw materials in parts by weight: 0.1 to 0.2 part of taurine, 30 to 50 parts of 50 percent ofa glucose injection, 0.3 to 0.6 part of a vitamin C injection, 0.0002 to 0.0006 part of a vitamin B12 injection and 0.04 to 0.1 part of an antibacterial stabilizer. By introducing the antibacterial stabilizer into the high-glucose eye drops disclosed by the invention, the eye drops are endowed with a better antibacterial effect; in addition, the preservative performance of a product is improved and the storage period of the eye drops is prolonged; the high-glucose eye drops can be produced in batches and are prepared into bottled products; patients from major hospitals can share the product,so the product can bring good treatment and prognosis to more patients.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a high-sugar eye drop. Background technique [0002] After eye trauma or surgery, some patients will experience corneal edema; patients with corneal ulcers also have different degrees of corneal dystrophy. For this reason, ophthalmology often adopts the "high-sugar eye drops" that are currently configured and drips them into the affected eye to treat corneal edema or nourish the cornea; It can only be prepared and used immediately. This kind of patients generally need eye drops 6 times / day or 1 time / hour. At the same time, the current high-sugar eye drops have relatively single functionality; therefore, how to produce eye drops that can be maintained for a long time and have strong functionality is the focus of current research. Contents of the invention [0003] The object of the present invention is to provide a kind of high-sugar eye drops aiming at the defects and deficiencies of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/714A61K31/7004A61K31/185A61K31/375A61K47/46A61K47/02A61K47/22A61K47/18A61P3/02A61P27/02
CPCA61K9/0048A61K31/185A61K31/375A61K31/7004A61K31/714A61K47/02A61K47/183A61K47/22A61K47/46A61P3/02A61P27/02A61K2300/00
Inventor 康玲刘勇奚蕾蔡佳馨杨俊容瞿婷
Owner THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
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