83 results about "Edema disease" patented technology

The invention discloses a traditional Chinese medicine composition and a feed for treating a piglet edema disease and preparation methods of the traditional Chinese medicine composition and the feed. The traditional Chinese medicine composition comprises plantain seeds, akebia stem, leonurus, dendrobium, small red beans, grifola, Chinese wax gourd peels, alisma, cyrtomium rhizome, manyleaf paris rhizome, gymnema, dogwood, prepared rehmannia roots, wolfberries and snakegourd roots. The traditional Chinese medicine composition and the feed for treating the piglet edema disease have the advantages of high cure rate, rapid treatment effect, no toxicity and side effects, less proneness to residual medicine production and the like.

The invention relates to a method for culturing a high-quality efficient stress-resistant complete set line of large white pigs, which comprises the following steps of: building a basic group based on gene identification and disease resistance verification of F18 colibacillosis resistant major genes FUT1M307 of a core group, and culturing the high-quality efficient stress-resistant complete set line of the large white pigs by combining immunology principle, molecular breeding technology and conventional breeding means and using a candidate gene strategy. The complete set line pigs have the advantages of stress resistance, strong environmental adaptability, weaned piglet diarrhea and edema disease resistance, high lean meat rate, excellent meat quality, high feed reward and high birth number.

The invention discloses macleaya cordata-coptis root powder. The macleaya cordata-coptis root powder comprises, by weight, 8-12 parts of macleaya cordata, 4-6 parts of coptis root and 4-6 parts of licorice root. The invention also discloses a production method of the macleaya cordata-coptis root powder. The production method comprises the following steps of weighing the above raw materials for next use, respectively crushing them and carrying out drying, adding the powder of macleaya cordata, coptis root and licorice root into a mixer in an equal quantity increasing way, and carrying out mixing for 15min to obtain the macleaya cordata-coptis root powder finished product. The invention also discloses a use of the macleaya cordata-coptis root powder. The macleaya cordata-coptis root powder is used for treating livestock transmissible gastroenteritis, edema diseases, diarrhea, pigling white diarrhea, yellow scour, high-fever diseases, viral diseases, fowl cholera and pullorum disease. The macleaya cordata-coptis root powder can be processed simply, has a low cost, can treat common bacterial infection of livestock and can improve a culture output and economic benefits.

The invention discloses a traditional Chinese drug composition for pig and a preparation method and application thereof. The composition comprises drug substances of 6-18 parts of indigofera tinctoria by weight, 4-12 parts of Chinese amphibious knotweed rhizome by weight and 5-15 parts of Chinese mosla herb by weight. The preparation method of the composition comprises: distilling Chinese mosla herb, and collecting the distillate; adding indigofera tinctoria and Chinese amphibious knotweed rhizome in the residue and residual liquid after distillation and decocting for 2-3 times, mixing the decoctive solution and concentrating the solution to viscous liquid, adjusting an alcohol concentration of ethanol to be 60 percent to 70 percent, precipitating, filtrating and concentrating the liquor, adding ethanol and adjusting the alcohol concentration to be 75 percent to 80 percent, sequentially performing precipitation, filtration and concentration of filter liquor, and adding distilled water and refrigerating for precipitation, filtration, and concentration; and blending the distillate of Chinese mosla herb with the collected concentrated solution of indigofera tinctoria and Chinese amphibious knotweed rhizome. The Chinese drug composition can be used for preparation of traditional Chinese veterinary drug to treat blue ear pig disease, porcine circovirus infection, pseudo rabies, piglet pullorum disease of piglet, paratyphoid of piglet, pig erysipelas and edema disease of piglet. Moreover, the Chinese drug composition has the advantages of few side effect and safe and convenient use.

The gene engineering vaccine for pigling weaning diarrhea (PWD) and pig edema disease (ED) belongs to the field of stockbreeding and veterinary technology. Primer containing specific cleavage site is first designed based on the faeG(F4), fedA(F18) and Stx 2e B subunit gene sequences; protective antigen gene is amplified through PCR process with PWD and ED colibucillus plasmid operate or genome DNA as template; said gene is directionally connected serially to the expressive plasmid pGEX-6P-1, used to transform host bacillus BL21 and IPTG inducing expressed; and the expression of the target gene is SDS-PAGE and Western-blot proved. The recombinant bacilli expressing the above-said three protective antigen genes are immunized to mouse and pig via different ways so as to evaluate the immunogenicity and safety. Test shows that the vaccine may be used to prevent PWD and ED effectively.

The invention relates to an additive, in particular to a feed additive applied to growth and development of a piglet. The additive is prepared from the following raw materials: astragalus, malt, acanthopanax, Chinese yam, honeysuckle, white paeony root, spina date seed, Chinese angelica and pearl barley in a weight part ratio of (10-20):(25-40):(3.0-15):(10-20):(1.0-10):(12-25):(5.0-20):(1.0-7.0):(20-35). Natural Chinese medicinal herbs are selected as raw materials according to requirements of physical characteristics and growth and development of the piglet, and are scientifically compatible, so that the additive facilitates the growth and enhances the physique of the piglet, wholly regulates the health of the piglet, improves the immunity of the piglet and reduces the death rate of weaned piglets, can prevent edema disease of the piglet, and reduces weaning stress of the piglet. The additive has no toxic or side effects, is safe and reliable in use and low in cost, and effectively improves the survival rate of the piglet.

The invention relates to a drug for preventing and treating swine edema disease and a method for further preparing injection, oral dosage and fodder additive. The drug is mainly made by the following components in weight proportion: plantain 150 g, Grassleaf Sweelflag Rhizome 100 g, poria coco 80 g and norfloxacin 150 mg. The drug and the various preparations have the advantages of good treating and preventing effect on swine edema disease and no poison or side effect.

The invention discloses a feed for preventing and controlling edema disease of swine, a Chinese medicinal composition and a preparation method. The feed comprises Chinese medicinal additives, montmorillonite, beer yeast, a trace element chelating agent, corn, hay and bacillus, wherein the Chinese medicinal additives comprise medicated leaven, rice-grain sprout, amomum fruit, large-head atractylodes rhizome, Chinese fever vine, baikal skullcap root, honeysuckle flower, cynanchum wilfordii, Chinese asafetida, ruddle, bamboo shavings, uncaria, tall gastrodia tuber, rhizoma arisaematis, borneol, dogbane leaf, common selfheal fruit-spike, akebia stem, umbellate pore fungus, oriental waterplantain rhizome, liquoric root, common andrographis herb, cyrtomium rhizome, paris rhizome, Indian trum etflower seed, plumed thistle root, beautiful sweetgum fruit and prickly knotweed. The feed provided by the invention contains the Chinese medicinal additives, has the functions of strengthening the spleen and stomach and clearing away heat and toxic materials, has the advantages of remarkable clinical effect, no toxic or side effect, low price, is easy and convenient to prepare, is capable of improving the body immunity and disease resistance of sick swine in the prevention and control of edema disease of swine, and has a certain health care function on consumers eating the type of pork.

The invention relates to a compound Furosemide injection for treating bowel oedema disease, wherein the formulation comprises Furosemide, Enrofloxacin, 40% sodium hydroxide, anti-oxidant, normal butyl alcohol and water for injection. The use of the compound preparation can reduce the stress of animal organism to injections.

There is provided an isolated E. coli strain deposited at the International Depositary Authority of Canada (IDAC) on Jun. 20, 2013 and attributed accession number 200613-01. There is also provided methods of using this strain for preventing edema disease or diarrhea caused by an F18 pathogenic E. coli infection in an animal.

The invention relates to an officinal and edible traditional Chinese medicine (TCM) combination for curing porcine diarrhea. The TCM combination mainly comprises the following components by the weight part: 120 to 140 parts of radix astragali, 40 to 60 parts of hawthorn coke, 40 to 60 parts of portulaca grandiflora, 40 to 60 parts of sedum sarmentosum, 40 to 60 parts of radish seed, 40 to 60 parts of abrus herb, 15 to 35 parts of liquorice, 15 to 35 parts of dried orange peel, 15 to 35 parts of indigowoad leaf, 15 to 35 parts of areca catechu, 15 to 35 parts of cherokee rose fruit, 35 to 55 parts of radix isatidis and 35 to 55 parts of coix seed. The components are prepared by the weight part, milled into fine powder and mixed in pig feed for feeding. The TCM combination has the main effect of curing bacterial, viral and other unexplained diseases with the cardinal symptoms being piglet diarrhea, bowel edema diseases and diarrhea, and has the advantages of quick-acting curative effect, short treatment period, low price, low relapse rate and no toxic and side effect; and the cure rate is higher than 99%.

The invention discloses a pharmaceutical composition for preventing and treating piglet edema diseases and a preparation method of the pharmaceutical composition. The pharmaceutical composition comprises the following raw herbal materials: cape jasmine, dysosma versipellis, dandelion, stephania japonica, peperomia blanda, isatis root, bunge corydalis herb, hypericum uralum, scirpus tabernaemontani, water primrose, fishing pole, roots of eichhornia crassipes solms, apricot and raphanus sativus. The pharmaceutical composition disclosed by the invention is mainly used for clearing heat, removing toxicity, alleviating water retention, diminishing swelling, freeing lung-qi and eliminating damp and also used for invigorating spleen to eliminate dampness, warming kidney, quieting spirit and stabilizing mind in an auxiliary manner, and has the advantages of good control efficiency, rapid effect, accurate curative effect, little side effect, low drug residue and the like for preventing and treating piglet edema diseases; after the pharmaceutical composition is used, the piglet edema disease is difficult to relapse, and the piglet does not generate drug resistance.

A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5′-untranslated region of an alcohol dehydrogenase gene (ADH5′UTR) derived from a plant.

The invention relates to a veterinary compound gentamycin sulfate injection and a preparation method thereof. The injection consists of gentamicin sulphate, ofloxacin, analgin, trimethoprim, an organic solvent and injection water. The injection serving as a veterinary special compound preparation is mainly used for treating porcine epidemic diarrhea, transmissible gastrocnteritis, paratyphus vaccine for piglets, yellow and white scour for piglets, edema disease for piglets, and intestinal diseases, such as poultry colibacillosis, fowl typhoid, paratyphoid and the like. The injection has the advantages of convenient use, short period of treatment, low medicament resistance and the like.

The invention discloses a method for preventing and curing piglet edema disease and belongs to the technical field of poultry disease prevention. The method for preventing and curing the piglet edema disease overcomes the disadvantages of an existing method for preventing and curing the piglet edema disease and is featured with thorough preventing and curing, quick effect and good effect. The method for preventing and curing the piglet edema disease includes that using suckling pig feed to induce from the seventh day so as to enable a piglet to adapt to vegetable feed before weaning; using the same feed for one week after weaning, and gradually changing into piglet feed after the week; within 3 weeks after weaning, using the piglet feed with less than or equal to 19% of protein and less than or equal to 15% of vegetable protein; in the first month after weaning, adding 1.00%-1.50% of citric acid to the feed or water; when the piglet is 3 weeks old, injecting iron blood tonic to the inner side of the inner thigh; adding sodium selenite vitamin E additive or intramuscular injection sodium nitrite injection to the feed; using the common medical feed additive. The method for preventing and curing the piglet edema disease is featured with low cost, easiness in operation, short time and quick effect and capable of curbing the disease source and reducing the unnecessary economic loss for the farmer.

The invention discloses piglet edema prevention pig feed. The piglet edema prevention pig feed is composed of, by weight, 70-80 parts of rape seed cake, 8-10 parts of corn, 4-5 parts of radix phytolaccae stem and leaf, 5-6 parts of garlic head, 3-4 parts of brown sugar, 2-3 parts of bone meal, 1-2 parts of zeolite powder, 13-15 parts of potato, 4-5 parts of cane sugar, 2-3 parts of urea and appropriate amounts of yeast, bacillus subtilis, aspergillus niger, oxytetracycline and water. Due to the cooperation of the raw materials in the piglet edema prevention pig feed, the edema disease of pigs can be prevented and treated, the requirement of piglets for nutrients can be met, the growth performance of the piglets is improved, and a certain health care effect can be achieved for organism of a consumer after the consumer eats pork of the type.

The invention relates to a TCM oral solution for treating a pig edema disease and a preparation method of the TCM oral solution. The TCM oral solution comprises the following components in parts by weight: 10-20 parts of chingma abutilon seed, 15-25 parts of Indian buead, 6-12 parts of radix isatidis, 5-10 parts of radix sophorae flavescentis, 15-20 parts of plantain seed, 5-10 parts of cimicifugae foetidae, 5-10 parts of radix astragal and 10-20 parts of liquorice. The TCM oral solution is extracted from natural Chinese herbal medicines and is efficient and stable in intestinal damp-heat and skin and body edema, so as to achieve the effect of treating both symptoms and root causes and the expected purpose of curing a disease; meanwhile, the dosage form of the drug is oral solution which can be quickly dispersed in feeding water, a sick pig drinks water to take the medicine, so that the absorption is facilitated, the use is safe, the non-toxic side effects are achieved, the process is simple, convenient and feasible, and the curative effect is significant.

The invention discloses a traditional Chinese medicine preparation for treating edema disease of swine and a preparation method thereof and relates to the technical field of prevention of the edema disease of swine. The traditional Chinese medicine preparation comprises, by weight, 12-20 parts of scutellaria baicalensis, 15-23 parts of pericarpium citri reticulatae, 10-18 parts of poria cocos peel, 13-18 parts of rhizoma atractylodis macrocephalae, 5-12 parts of ramulus cinnamomi, 9-19 parts of cortex phellodendri, 8-17 parts of rhizoma alismatis, 3-11 parts of rhizoma atractylodis, 5-13 parts of coptis chinensis, 7-16 parts of cortex mori, 12-19 parts of glycyrrhiza radix and appropriate water. The Chinese medicinal herb treatment method which is free of antibiotics, material available, low in cost, good in treatment effect and capable of effectively preventing and controlling epidemic is provided, risk of major farmers raising swine is lowered to a great extent, and the added Chinese herbs have the efficacy of dissipating heat and drying damp, regulating qi-flowing for strengthening the spleen, and promoting urination to remove damp.

The invention discloses a traditional Chinese medicinal composition for treating edema disease of a bamboo rat. The traditional Chinese medicinal composition consists of the following raw medicinal materials in parts by weight: 2-4 parts of cordate houttuynia, 2-4 parts of blackberry lily, 2-4 parts of dandelion, 2-4 parts of sculellaria barbata, 2-4 parts of coptis chinensis and 2-4 parts of root of Chinese pulsatilla, and the composition is prepared by mixing or decocting the various traditional Chinese medicinal raw materials after respectively grinding. The traditional Chinese medicinal composition has the functions of clearing away heat and toxic materials, relieving swelling and pain, resisting inflammation, stopping blooding, removing dampness, killing parasites and the like; the composition is good in antibacterial performance, has a relatively good effect on inhibiting or killing escherichia coli and not easy to result in drug resistance, and is capable of enhancing immunity of the bamboo rat, reducing use of biotic, avoiding abuse of the biotic and benefiting for health of the bamboo rat. The traditional Chinese medicinal composition has relatively high curative rate and effective rate on treating edema disease of the bamboo rat, and is stable in effectiveness; the composition is abundant in crude medicine resource, appropriate in proportion and convenient to use and has an obvious treatment effect.

The present invention provides a piglet edema disease prevention and treatment feed and a production method thereof, and belongs to the technical field of husbandry, wherein the piglet edema disease prevention and treatment feed is prepared by mixing the following raw materials by weight: 30-35 parts of fermented bean meal, 15-20 parts of milk powder, 8-10 parts of corn germ powder, 0.5-0.8 part of bone powder, 0.8-1.0 part of sucrose, 0.2-0.4 part of edible salt, 0.8-1.0 part of an additive, 0.2-0.4 part of an enzyme preparation, and 1.0-1.5 part of a plant extraction agent. The present invention further provides the production method of the feeding feed. According to the present invention, the feed is formed through the scientific combination, and is rich in bioactive substances; and the effective ingredients of various raw materials interact and synergistically act so as to provide effects of piglet intake promoting, piglet immunity improving, piglet disease resistance improving, edema disease incidence reducing, piglet growth nutrition supplementing, absorption and digestion promoting, healthy and rapid pig growth promoting, pig meat quality improving, and pork eating safety improving.

The invention discloses a cultivation induction method for parent misgurnus anguillicaudatus and relates to the field of aquaculture. The method comprises the following steps: treating pond water in a cultivation pond by using a traditional Chinese medicine composition; putting the bred parent misgurnus anguillicaudatus into the cultivation pond, and cultivating the parent misgurnus anguillicaudatus with self-made feeds, wherein animal proteins and plant proteins account for 50 percent respectively, the content of the proteins is 35 percent, and the content of fat is 5 percent; feeding the parent misgurnus anguillicaudatus for two times every day, wherein the feeding amount is 3-5 percent of the body weight of the parent misgurnus anguillicaudatus, water is yellow green and keeps rich and clear, the transparency is 15-20 cm, and the water temperature is 15-25 DEG C; washing for two times every week, changing a quarter of pond water at each time, dissecting regularly to check gonad development, timely adjusting a work plan, and preventing the putrid-skin disease, the edema disease, the trichodiniasis, the chilodonelliasis and the bird damage of misgurnus anguillicaudatus. According to the cultivation induction method for the parent misgurnus anguillicaudatus provided by the invention, by virtue of breeding and strengthened cultivation, the physical health of the parent misgurnus anguillicaudatus is improved, the brood amount is large, and the spawning induction fertilization rate is high. Moreover, the pond water in the cultivation pond is treated by using the traditional Chinese medicine composition, germs and parasites in a water body are killed, the traditional Chinese medicine composition can promote the misgurnus anguillicaudatus to forage, and the aim of cultivation induction is achieved.

The invention relates to mixing antiseptic injection of barbat skullcap and radical lobelia, and process for preparation. The antiseptic injection of barbat skullcap and radical lobelia is proportioned by weight, which comprises radical lobelia extract 54-48%, barbat skullcap extract 46-52%, sodium hydrogen sulfite 0.2%, disodium edentate 0.02%, and the sum weight of every 100g radical lobelia extract and barbat skullcap extract is matched with 800-1200ml injection water. The process for preparation of injection of barbat skullcap and radical lobelia is as follows: radical lobelia extract and barbat skullcap extract are homogeneously mixed and stirred evenly after charging injection water and activated carbon which is removed through filtering after 8-20 hours still in position, and then the sodium hydrogen sulfite and the disodium edentate are charged, pH valve is adjusted to 5.0-7.0, and injection of barbat skullcap and radical lobelia is obtained after fine filtration. The effective rate of treatment of injection of barbat skullcap and radical lobelia to mixing injection of bacteria and virus, swine edema disease, respiratory tract infections and cow mastitis can reach above 90%, whereas the effective rate of treatment of barbat skullcap injection is only about 70%.

The invention discloses a traditional Chinese medicine granule for improving sub-health of piglets through breast milk, and a preparation method of the traditional Chinese medicine granule. Active components are extracted from traditional Chinese medicine extracts in raw materials by adopting a specific extraction method; natural plant components are added; part of raw materials are pretreated; the pretreated raw materials can enhance effects of the traditional Chinese medicine extracts and the natural plant components; the traditional Chinese medicine granule prepared by combining three materials is fed to sows, so that the breast milk of the sows can reduce the occurrence of cad pigs, but also can enhance the disease resistance of newborn animals and female animals, and further has the effect of preventing and treating the edema disease of pigs.

The invention relates to a traditional Chinese medicinal composition for treating the piglet edema disease and a preparation method of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition is prepared from the following medicinal materials in parts by weight: 1-10 parts of white atractylodes rhizome, 1-10 parts of mirabilite, 1-5 parts of rhizoma coptidis, 1-5 parts of cortex phellodendri, 1-10 parts of rhizoma alismatis, 1-10 parts of poria cocos, 1-5 parts of fructus aurantii, 1-5 parts of medicated leaven, 1-5 parts of herba commelinae, 1-10 parts of herba plantaginis, and 1-5 parts of licorice root. The traditional Chinese medicinal composition has the efficacies of clearing away heat and toxic materials, as well as relieving sore-throat and wetting the laryngopharynx, is simple in preparation method, convenient to use, low in price, small in toxic and side effects, and free of drug residue, and belongs to a good traditional Chinese medicinal composition for treating the piglet edema disease.

The invention discloses a pharmaceutical composition for treating edema diseases and cardiovascular and cerebrovascular diseases, in particular an oral drop pill preparation of the pharmaceutical composition with spironolactone as an active ingredient. The purpose of the present invention is to make up for the deficiencies of the prior art, to provide patients and medical workers with a medicine with large drug loading capacity, rapid drug release, rapid effect, high bioavailability, small toxic and side effects, low price and easy to take. Spironolactone drop pills. Take spironolactone as raw material, add surfactant polyethylene glycol and other substrates, heat until the pharmaceutical composition melt and / or emulsion and / or suspension containing spironolactone and substrate are obtained, put it into the dropping pill machine, drop into It is formed by shrinking in a condensing agent, taken out and wiped dry.

The invention discloses a compound injection for preventing and treating an edema disease of a piglet and a preparation method of the compound injection. The compound injection comprises the following components in parts by weight: 5-20 parts of enrofloxacin, 0.25-5 parts of furosemide, 50-300 parts of ethanol, 50-300 parts of propylene glycol and 400-900 parts of injection water. The preparation method comprises the following steps: gradually dissolving the components successively; adjusting the pH to be 9.5-10.5 by using hydrochloric acid or sodium hydroxide; and adding injection water to 1,000 parts, thereby preparing the compound injection. The preparation prepared by the preparation method disclosed by the invention is stable, wide in antibacterial spectrum, fast and significant in curative effect, and high in bioavailability. The experiment proves that the curative effect can be enhanced by joint use of enrofloxacin and furosemide, the compound injection is wide in clinical application, can be used as a choice drug for treating the edema disease of the piglet, the survival rate of the piglet is increased, and the morbidity is reduced.

The invention discloses a health-care-type puffed compound feed for yellow catfishes and a preparation method thereof. The feed comprises natural pigments and health-care components, wherein the natural pigments comprise cape jasmine fruit powder, Ningxia wolfberry fruit residues, all grass of planis corepsis powder and corn protein powder; and the health-care components comprise pine needle powder, cape jasmine fruit powder, Ningxia wolfberry fruit residues, all grass of planis corepsis powder and baikal skullcap roots. The feed solves the problem of keeping the body color of the yellow catfishes close to a natural body color and improving the immunity and the disease resistance of the yellow catfishes without the addition of artificial extracting pigment, and the feed can effectively reduce the incidence of hemorrhagic edema disease, split head disease and enteritis, and improve the survival rate of fry, has the effects of promoting growth, and can effectively reduce the feed coefficient of the yellow catfishes and improve culturing benefits.

The invention discloses a preparation method of a shiga-like toxin Stx1B oral vaccine, which concretely comprises the steps of: cloning a shiga-like toxin Stx1B gene, building a recombinant expression vector containing the Stx1B gene, then preparing a transgenic plant, and finally preparing the shiga-like toxin Stx1B oral vaccine. The prepared shiga-like toxin Stx1B oral vaccine can be directly and orally taken to immunize and can effectively prevent the escherichia coli O157:H7 infection, moreover, the orbidity of edema disease of a pig is reduced, and the death efficiency is also reduced at the same time.

The invention relates to a veterinary drug composition for preventing porcine diarrheal disease. The composition is prepared from 5-35 parts of enrofloxacin, 5-35 parts of sulfadiazine sodium, 5-30 parts of TMP, 10-35 parts of radix sophorae flavescentis extract, 8-35 parts of rhizoma atractylodis macrocephalae extract, 10-35 parts of radix pulsatillae extract, injection water and the like. The veterinary drug composition provided by the invention has the characteristics of clearing heat and removing toxin, fighting bacteria and diminishing inflammation, astringing intestines and checking diarrhea, clearing bowels and killing worms, promoting digestion and removing mass, promoting digestion, draining water and dispersing swelling, promoting discharge of enterotoxin, accelerating repair of intestinal mucosa, enhancing the contraction of gastrointestinal smooth muscle and the like, and can effectively prevent the porcine diarrheal disease; moreover, the veterinary drug composition can effectively prevent the yellow and white scour of piglet, and realizes an obviously effect of early prevention of porcine edema disease; by injecting the veterinary drug composition into the newly born piglet, the piglet can be protected from the yellow and white scour and edema disease throughout the life; and by injecting the veterinary drug composition into the livestock before birth, after birth, during weaning, after purchasing and in long-distance transportation, the disease can be effectively prevented.

An object of the present invention is to provide a method for preventing diseases in weaned piglets, which relieves the stress of postweaning piglets and enhances the immunostimulating ability in order to prevent the death due to colibacillosis such as edema disease in postweaning piglets and to increase the rate of raising.Pig diseases such as colibacillosis, particularly diarrhea, can be prevented by administering a Grifola-derived substance selected from one or more of dried Grifola, dried Grifola powder and a Grifola extract to pigs in weaning period, so as to solve the problems of the present invention.