Furosemide compound injection for treating pigling edema disease

Abstract

The invention relates to a compound Furosemide injection for treating bowel oedema disease, wherein the formulation comprises Furosemide, Enrofloxacin, 40% sodium hydroxide, anti-oxidant, normal butyl alcohol and water for injection. The use of the compound preparation can reduce the stress of animal organism to injections.

Description

technical field

[0001] The invention relates to a compound furosemide injection for treating piglet edema. Background technique

[0002] Piglet edema is caused by toxins produced by certain hemolytic Escherichia coli and is a common disease in post-weaning piglets. The disease often occurs in weaned piglets, especially in obese piglets.

[0003] Symptoms: Sudden onset, normal body temperature, unsteady gait, dangerous eyes, edema of the head and neck, indentation in the edema part of finger pressure, agitation soon, blind walking or turning in circles. Autopsy: The main lesion was edema, the most obvious edema was in the greater curvature of the stomach, and the large intestine and small mesentery were highly edematous.

[0004] The threat of piglet edema to the pig industry has become more and more serious in recent years, and the losses to the pig industry are quite huge every year. In recent years, there is still no ideal specific drug for the treatment of piglet edema...

Examples

Embodiment 1

[0058] Take the following raw materials according to the formula

[0059] Furosemide 100g

[0060] Enrofloxacin 250g

[0061] 40% Sodium Hydroxide 91ml

[0062] Antioxidant (sodium bisulfite) 18g

[0063] Butanol 150ml

[0064] Add water for injection to 10000ml.

[0065] The specific production operation method is as follows:

[0066]Take the formula amount of furosemide, add water 4000ml, add 40% sodium hydroxide 25ml to dissolve; then take the formula amount of enrofloxacin, add water 4000ml, add 40% sodium hydroxide 66ml to dissolve, add sodium bisulfite, n-butanol , mix the two solutions, adjust the pH to 9.8---10.5 with 40% sodium hydroxide, add water to 10000ml, filter, fine filter until clear, potting, and sterilize at 100°C for 30 minutes to obtain the prepared 10000ml ml of product.

technical field

[0001] The invention relates to a compound furosemide injection for treating piglet edema. Background technique

[0002] Piglet edema is caused by toxins produced by certain hemolytic Escherichia coli and is a common disease in post-weaning piglets. The disease often occurs in weaned piglets, especially in obese piglets.

[0003] Symptoms: Sudden onset, normal body temperature, unsteady gait, dangerous eyes, edema of the head and neck, indentation in the edema part of finger pressure, agitation soon, blind walking or turning in circles. Autopsy: The main lesion was edema, the most obvious edema was in the greater curvature of the stomach, and the large intestine and small mesentery were highly edematous.

[0004] The threat of piglet edema to the pig industry has become more and more serious in recent years, and the losses to the pig industry are quite huge every year. In recent years, there is still no ideal specific drug for the treatment of piglet edema...

Examples

Embodiment 1

[0058] Take the following raw materials according to the formula

[0059] Furosemide 100g

[0060] Enrofloxacin 250g

[0061] 40% Sodium Hydroxide 91ml

[0062] Antioxidant (sodium bisulfite) 18g

[0063] Butanol 150ml

[0064] Add water for injection to 10000ml.

[0065] The specific production operation method is as follows:

[0066]Take the formula amount of furosemide, add water 4000ml, add 40% sodium hydroxide 25ml to dissolve; then take the formula amount of enrofloxacin, add water 4000ml, add 40% sodium hydroxide 66ml to dissolve, add sodium bisulfite, n-butanol , mix the two solutions, adjust the pH to 9.8---10.5 with 40% sodium hydroxide, add water to 10000ml, filter, fine filter until clear, potting, and sterilize at 100°C for 30 minutes to obtain the prepared 10000ml ml of product.