Chinese traditional medicine preparation for treating cervicitis

A traditional Chinese medicine preparation and cervicitis technology, which is applied in the field of traditional Chinese medicine, can solve the problems of restricting the full application of drugs and not being able to fully explore the active ingredients of drugs, and achieve good anti-cervicitis effects, improved anti-cervicitis effects, and promotion of uterine muscle peristalsis. Effect

Active Publication Date: 2008-07-30
GUANGZHOU YIPINHONG PHARMA +5
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method of dry extract is relatively simple, and the active ingredients of the drug cannot be fully explored, which limits the full application of the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Wash 5 kg of Guangdong purple pearl and 2 kg of motherwort with clean water, and then dry them at 50 ° C. Grind the dried Guangdong purple pearl and motherwort to 20 mesh fine powder, and combine the crushed Guangdong purple pearl and motherwort for use The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by Hanwei (HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 45°C, the extraction pressure is 30mPa, and the extraction time is 2 hours; The hydrophilic effective active substance is extracted by alcohol extraction and water precipitation method, the volume concentration of ethanol is 75%, and the alcohol extraction temperature is 80°C. Concentrate the alcohol extract to a relative density of 1.2 (at 80°C), add 5.5 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate and dry it in vacuum at 80°C to obtain a dry extract. Take dry extract with 350g PEG 400 After...

Embodiment 2

[0021] Clean 6 kg of Guangdong purple pearl and 1 kg of motherwort with clean water, and then dry them at 50 ° C. Grind the dried Guangdong purple pearl and motherwort to 20 mesh fine powder, and combine the crushed Guangdong purple pearl and motherwort for use The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by Hanwei (HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 50°C, the extraction pressure is 25mPa, and the extraction time is 1.5 hours; The effective hydrophilic active substance is extracted by alcohol extraction and water precipitation method, the volume concentration of ethanol is 90%, and the alcohol extraction temperature is 70°C. Concentrate the alcohol extract to a relative density of 1.0 (at 80°C), add 7 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate and dry it in vacuum at 80°C to obtain a dry extract. Take dry extract with 360g PEG 400 Afte...

Embodiment 3

[0024] Wash 5 kg of Guangdong purple pearl and 1 kg of motherwort with clean water, and then dry them at 50 ° C. Grind the dried Guangdong purple pearl and motherwort to 20 mesh fine powder, and combine the crushed Guangdong purple pearl and motherwort for use The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by Hanwei (HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 60°C, the extraction pressure is 28mPa, and the extraction time is 1.5 hours; The effective hydrophilic active substance is extracted by alcohol extraction and water precipitation method, the volume concentration of ethanol is 90%, and the alcohol extraction temperature is 70°C. Concentrate the alcohol extract to a relative density of 1.0 (at 80°C), add 5 times the amount of water, stir well, let stand for 5 hours, filter, and vacuum-dry the precipitate at 80°C to obtain a dry extract. Take dry extract with 380g PEG 400 After stirring a...

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PUM

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Abstract

The invention discloses a traditional Chinese preparation for cervicitis treatment; and the invention consists of the following components by weight portion: kwangtung beautyberry of 5 to 6 portions and leonurus japonicus of 1 to 2 portions. The invention is high in the efficiency of extracting lipophilic effective active compositions from the kwangtung beautyberry and the leonurus japonicus with a carbon dioxide supercritical fluid extracting device without respectively preparing extracts or solvent residual toxicity, and natural active compositions and heat sensitive ingredients are not easily decomposed and destroyed, which can keep the natural characteristics of the extracts to the greatest extent; hydrophilic active compositions are further extracted from herbal residues which are extracted super critically with the ethanol water extraction precipitation and effective compositions with various properties are completely extracted; the extracting method of the invention can fully excavate active compositions of raw medicine and the obtained active compositions are greatly different from extracts used in the prior art, which greatly increases the anti-cervicitis effect; the invention can play a good anti-cervicitis role without adding combined spicebush, which reduces the cost.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating cervicitis. Background technique [0002] Cervicitis is a frequently occurring gynecological disease. The general treatment adopts the theory of traditional Chinese medicine, utilizes some Chinese herbal formulas, and cooperates with oral administration and external application, but the therapeutic effect is not very satisfactory. [0003] The main components of the existing anti-cervicitis medicine are Guangdong Zizhu dry extract, Motherwort dry extract and Wuyao dry extract. The preparation method of the dry extract is relatively simple, and the active ingredients of the medicine cannot be fully explored, which limits the full application of the medicine. Contents of the invention [0004] The purpose of the present invention is to overcome the problems existing in the prior art and provide a traditional Chin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61P15/00
Inventor 王勇
Owner GUANGZHOU YIPINHONG PHARMA
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