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Pharmaceutical composition for anti-inflammation ease-pain

An anti-inflammatory, analgesic and composition technology, which can be used in drug combinations, antipyretics, anti-inflammatory agents, etc., and can solve the problems of low anticoagulant activity and volatilization of antipyretic effects.

Inactive Publication Date: 2008-09-10
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

4. Low anticoagulant activity
Its antipyretic effect is central, and the most obvious effect is to cool down through sweating, but its antipyretic effect does not completely depend on the volatilization of sweat.

Method used

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  • Pharmaceutical composition for anti-inflammation ease-pain
  • Pharmaceutical composition for anti-inflammation ease-pain

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0027] 1. Preparation of compound chondroitin sulfate diclofenac sodium water injection (10ml / bottle)

[0028] Prescription: Diclofenac Sodium 75g

[0029] HP-β-CD 250g

[0030] Chondroitin Sulfate 200g

[0031] Vitamin C 1g

[0032] Add water for injection to 10000m1

[0033] Preparation Process:

[0034] Take HP-β-CD, add it to about 500ml of water for injection, heat it to about 50°C, add the prescribed amount of diclofenac sodium and vitamin C, the solution becomes cloudy at first, continue to stir for about 1 hour, and the solution becomes clear; take another chondroitin sulfate , Add to about 3000ml water for injection, stir to dissolve. Mix the two solutions evenly, add water to about 9000ml, adjust the pH value of the solution to 4.0-7.0, add 50g of activated carbon for needles, keep it warm for 20 minutes, decarbonize while it is hot, add water for injection from the filter to the full amount, and fine filter with a 0.22um filter membrane....

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Abstract

The invention provides an anti-inflammatory and pain-killing medical composition; chondroitin sulfate and a non-steroidal anti-inflammatory agent are used as active ingredients and mixed with a medical carrier to form the composition. Non-steroidal anti-inflammatory agent includes but not confines in diclofenac sodium (potassium), naprosyn and Lornoxicam; the composition exists in forms of squirt, freeze-dried powder and large-capacity transfusion for intravenous medication of a human body. The composition can be applied to symptomatic treatments of various febrile illnesses, various arthritises and inflammatory rheumatic diseases, soft tissue rheumatisms, neuralgia, arthralgia and pains, wounds relevant to degenerative diseases of spines, or postoperative pains.

Description

technical field [0001] The invention relates to a pharmaceutical composition for anti-inflammatory and analgesic injection, a preparation method and application thereof, and belongs to the technical field of medicine. Background technique [0002] Chondroitin sulfate is widely found in human and animal cartilage tissue. Its medicinal preparation mainly contains two isomers of chondroitin sulfate A and chondroitin sulfate C, and the content of chondroitin sulfate in cartilage of different species and ages is different. Its pharmacological effects are as follows: 1. Chondroitin sulfate can remove lipids and lipoproteins in the blood in the body, remove cholesterol in blood vessels around the heart, prevent and treat atherosclerosis, and increase the conversion rate of lipids and fatty acids in cells. 2. Chondroitin sulfate can effectively prevent and treat coronary heart disease. It has anti-atherosclerosis and anti-atherosclerotic plaque formation effects on experimental ar...

Claims

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Application Information

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IPC IPC(8): A61K31/737A61K31/196A61K31/192A61K31/542A61P29/00
Inventor 路洪书
Owner FUKANGREN BIO PHARMA
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