Novel therapeutic applications of Fengshi maqian tablet and quality control method

A quality control method and technology of nuxon tablets, applied to medical preparations containing active ingredients, pharmaceutical formulas, measuring devices, etc., can solve the problem of large content fluctuation range, difficulty in ensuring that the finished product meets the standard regulations, and the liquid medicine Deterioration and other issues

Inactive Publication Date: 2008-10-08
王世锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the large fluctuation range of the content of strychnine in Nuxychia, it is difficult to ensure that the strychnine in the finished product meets the standard requirements by feeding the prescription; the percolation method takes a long time to produce, the liquid is easy to deteriorate, and the quality control standards lack qualitative and precise standards. detection methods etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Prescription composition: Nuxychia powder 150g silkworm (stir-fried) 19g frankincense (stir-fried) 19g myrrh (stir-fried) 19g scorpion 19g Achyranthes bidentata 19g herb atractylodes 19g ephedra 19g licorice 19g.

[0022] Preparation method: the above nine flavors, except Nuxychnium powder, scorpion, frankincense, myrrh and silkworm are crushed into fine powder, ephedra and atractylodes are added with 8 times the amount of 70% ethanol and refluxed twice, recovered ethanol, concentrated into relative Ointment with a density of 1.23-1.26 (70°C); decoct licorice and Achyranthes bidentata with 10 times the amount of water for three times, 1 hour each time, filter, and combine the filtrates; concentrate into an ointment with a relative density of 1.23-1.26 (70°C); combine the above Ointment, take nuxe seed powder, scorpion, frankincense, myrrh and silkworm fine powder and mix evenly, use the above-mentioned combined ointment as adhesive spray granulation, granulate, add 9g of...

Embodiment 2

[0023] Example 2: Nuxychnium powder 150g silkworm (stir-fried) 19g frankincense (stir-fried) 19g myrrh (stir-fried) 19g scorpion 19g achyranthes bidentata 19g atractylodes atractylodes 19g ephedra 19g licorice 19g.

[0024]Preparation method: the above nine flavors, except Nuxychnium powder, scorpion, frankincense, myrrh and silkworm are crushed into fine powder, ephedra and atractylodes are added with 8 times the amount of 70% ethanol and refluxed twice, recovered ethanol, concentrated into relative Ointment with a density of 1.15-1.20 (70°C); decoct licorice and Achyranthes bidentata with 10 times the amount of water for three times, each time for 1 hour, filter, and combine the filtrate; concentrate into an ointment with a relative density of 1.15-1.20 (70°C); combine the above Ointment, spray-dried (inlet air temperature 250°C, air outlet temperature 80-120°C) to make extract powder, mix with nuxychonium powder, scorpion, frankincense, myrrh and silkworm fine powder, and us...

Embodiment 3

[0025] Example 3: Nuxychnium powder 150g silkworm (stir-fried) 19g frankincense (stir-fried) 19g myrrh (stir-fried) 19g scorpion 19g achyranthes bidentata 19g atractylodes atractylodes 19g ephedra 19g licorice 19g.

[0026] Preparation method: the above nine flavors, except Nuxychnium powder, scorpion, frankincense, myrrh and silkworm are crushed into fine powder, ephedra and atractylodes are added with 8 times the amount of 70% ethanol and refluxed twice, recovered ethanol, concentrated into relative Ointment with a density of 1.15-1.20 (70°C); decoct licorice and Achyranthes bidentata with 10 times the amount of water for three times, each time for 1 hour, filter, and combine the filtrate; concentrate into an ointment with a relative density of 1.15-1.20 (70°C); combine the above Ointment, spray-dried (inlet air temperature 250°C, outlet air temperature 80-120°C) to make extract powder, mix with nuxychon seed powder, scorpion, frankincense, myrrh and silkworm fine powder, and...

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PUM

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Abstract

The invention aims at providing medicine combination with the proportion of 150g of semen powder, 19g of olibanum (fried), 19g of myrrh (fried), 19g of scorpion, 19g of achyranthes root, 19g of atractylodes, 19g of ephedra and 19g of glycyrrhia. The medicine combination and excipient acceptable for pharmacy undergo the processes of reflux extraction, condensation, extract drying, grinding, granulation, pill making, capsule filling and tablet pressing to be made into acceptable preparation including a particle, an effervescent granule, a conventional tablet, the chewable tablet, the effervescent tablet, a capsule, the soft capsules and a pill, thus becoming the new preparation of Ma Qian tablet for rheumatic. The invention provides the new treating application of the medicine combination for cervical spondylosis, lumbar disc herniation, hyperosteogeny and femoral head necrosis (FHN).

Description

technical field [0001] The invention relates to a preparation process of a medicine, a new therapeutic use and a quality control method, in particular to a new therapeutic use and a quality control method of Fengshi Maqian tablets. Background technique [0002] Rheumatism Nuxvous Tablets is a variety recorded in the eighth volume of the ministerial standard, and the prescription is composed of: Nuxychia (made) 313g silkworm (stir-fried) 38g frankincense (stir-fried) 38g myrrh (stir-fried) 38g scorpion 38g Achyranthes bidentata 38g atractylodes 38g ephedra 38g licorice 38g; the preparation method is: nuxychia, scorpion, frankincense, myrrh and silkworm are pulverized into fine powder; ), use 70% ethanol as a solvent, carry out percolation, collect the filtrate, reclaim ethanol, concentrate into a thick paste; add water to decoct licorice and Achyranthes bidentata three times, each time for 1 to 2 hours, filter, and combine the filtrate; concentrate into a thick paste . Comb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/56A61K9/48A61K9/20A61K9/46A61K9/16G01N30/90G01N30/02A61P19/08A61P19/10A61K35/64
Inventor 王世锋
Owner 王世锋
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