Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases

An allergy and composition technology, applied in the field of medicine, can solve problems such as high tolerance, large toxic and side effects, and complicated pathogenesis

Active Publication Date: 2009-05-20
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pathogenesis of asthma is very complicated, it is an inflammatory disease caused by multiple factors and involved by multicellular mediators, it is difficult for the above-mentioned drugs with a single mechanism of action to meet the needs of clinical treatment, which makes the long-term treatment of asthma prone to relapse and high tolerance. , strong dependence, large toxic and side effects, etc.

Method used

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  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0135] Codonopsis 300g, Polygonatum 400g, Panax notoginseng 60g, Amber 40g, Natsumi 200g, amber is crushed into fine powder, Natsumi extracts volatile oil, and the distilled aqueous solution is collected in another device; Panax notoginseng is crushed into coarse powder, extracted twice with 80% ethanol , for 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.25-1.30 (60°C), and decoct Panax notoginseng and Gansong dregs with Codonopsis pilosula and Polygonatum twice in water for the first time 2 hours, 1.5 hours for the second time, combine the decoction liquid and the above distilled aqueous solution of nard pine, filter, concentrate the filtrate to a clear paste with a relative density of 1.20-1.25 (60°C), add ethanol to make the alcohol content reach 65 %, stir, stand still for 48 hours, filter the supernatant, concentrate under reduced pressure to a clear paste with a relative density of 1.25-1...

Embodiment 2

[0137] Codonopsis 300g, Polygonatum 400g, Panax notoginseng 60g, Amber 40g, Natsumi 200g, amber is crushed into fine powder, Natsumi extracts volatile oil, and the distilled aqueous solution is collected in another device; Panax notoginseng is crushed into coarse powder, extracted twice with 80% ethanol , for 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.25-1.30 (60°C), and decoct Panax notoginseng and Gansong dregs with Codonopsis pilosula and Polygonatum twice in water for the first time 2 hours, 1.5 hours for the second time, combine the decoction liquid and the above distilled aqueous solution of nard pine, filter, concentrate the filtrate to a clear paste with a relative density of 1.20-1.25 (60°C), add ethanol to make the alcohol content reach 65 %, stir, stand still for 48 hours, filter the supernatant, concentrate under reduced pressure to a clear paste with a relative density of 1.25-1...

Embodiment 3

[0139] Codonopsis 300g, Polygonatum 400g, Panax notoginseng 60g, Amber 40g, Natsumi 200g, amber is crushed into fine powder, Natsumi extracts volatile oil, and the distilled aqueous solution is collected in another device; Panax notoginseng is crushed into coarse powder, extracted twice with 80% ethanol , for 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.25-1.30 (60°C), and decoct Panax notoginseng and Gansong dregs with Codonopsis pilosula and Polygonatum twice in water for the first time 2 hours, 1.5 hours for the second time, combine the decoction liquid and the above distilled aqueous solution of nard pine, filter, concentrate the filtrate to a clear paste with a relative density of 1.20-1.25 (60°C), add ethanol to make the alcohol content reach 65 %, stirred, and stood still for 48 hours, filtered the supernatant, concentrated under reduced pressure to a clear paste with a relative density...

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Abstract

The invention relates to novel application of a pharmaceutical composition to preparing a medicine for preventing and treating allergic diseases. The prescription consists of the following materials: 300 portions of radix codonopsis pilosulae, 400 portions of rhizoma polygonati, 60 portions of radix notoginseng, 40 portions of amber, and 200 portions of nard, and the formulation includes pill, granule, hard capsule, soft capsule, tablet, dripping pill or oral taking liquid. The aim of the invention is to provide novel treatment application of the pharmaceutical composition, which widens the clinical application range of the invention, and avoids waste of good medicine resources.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition in the preparation of medicines for preventing and treating allergic diseases. Background technique [0002] Allergy, also known as anaphylaxis, hypersensitivity, refers to the abnormal or pathological immune response that occurs when a body that has been sensitized by a certain antigen is stimulated again by the same antigen, which is manifested as physiological dysfunction or tissue cell damage. According to the mechanism of allergic reaction, it is usually divided into type IV. The first three types are mediated by antibodies, and type IV is mediated by cellular immunity. Clinically, two or three types of allergic reactions often coexist, with one being the main type. An antigen can cause different types of allergic reactions under different conditions. Type I has the highest incidence rate among all types of allergies, inclu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P37/08A61P17/00A61P11/06A61P11/02A61P27/02A61K35/10
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA
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