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Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases

An allergy, composition technology

Active Publication Date: 2011-01-26
SHANXI BUCHANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pathogenesis of asthma is very complicated, it is an inflammatory disease caused by multiple factors and involved by multicellular mediators, it is difficult for the above-mentioned drugs with a single mechanism of action to meet the needs of clinical treatment, which makes the long-term treatment of asthma prone to relapse and high tolerance. , strong dependence, large toxic and side effects, etc.

Method used

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  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
  • Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0137] Take 27g of earthworm and 13g of scorpion for use by superfine grinding; the remaining 66g of astragalus, 27g of red peony root, 27g of salvia miltiorrhiza, 27g of angelica, 27g of chuanxiong, 27g of peach kernel, 13g of safflower, 13g of frankincense, 13g of myrrh, and 20g of milletanus , 27g of Achyranthes bidentata, 20g of cassia twig, 27g of mulberry branch, 27g of leech and other fourteen medicinal materials are ultrafinely ground into fine powder, blended with the above powder, sieved, mixed evenly, add appropriate amount of starch, sodium carboxymethyl cellulose, Stevioside, mixed and passed through 80-mesh sieve, added appropriate amount of water to granulate, dried under reduced pressure at 60°C, granulated, packaged separately, and made into 1000g granules. Usage and dosage: Take 0.8-1.9g once, 3 times a day.

Embodiment 2

[0139] Take 27g of earthworm and 13g of scorpion for use by superfine grinding; the remaining 66g of astragalus, 27g of red peony root, 27g of salvia miltiorrhiza, 27g of angelica, 27g of chuanxiong, 27g of peach kernel, 13g of safflower, 13g of frankincense, 13g of myrrh, and 20g of milletanus , 27g of Achyranthes bidentata, 20g of cassia twig, 27g of mulberry branch, 27g of leech and other fourteen medicinal materials are ultrafinely ground into fine powder, blended with the above powder, sieved, mixed evenly, added starch, mixed evenly, granulated and loaded Capsules, made into 1000g hard capsules. Usage and dosage: Take 0.8-1.6g once, 3 times a day.

Embodiment 3

[0141] Take 27g of earthworm and 13g of scorpion for use by superfine grinding; the remaining 66g of astragalus, 27g of red peony root, 27g of salvia miltiorrhiza, 27g of angelica, 27g of chuanxiong, 27g of peach kernel, 13g of safflower, 13g of frankincense, 13g of myrrh, and 20g of milletanus , Achyranthes bidentata 27g, cassia twig 20g, mulberry branch 27g, leech 27g and other fourteen medicinal materials are ultrafinely pulverized into fine powder, compounded with the above powder, sieved, and mixed. Melt the gelatin, water and glycerin (1:1:0.3-0.45) and keep it warm for later use. Add an appropriate amount of vegetable oil (soybean oil or salad oil) to the medicine powder and mix well. Grind it into a uniform and viscous paste with a colloid mill. Degassing, pressing, and making 1000g soft capsules. Usage and dosage: Take 0.8-1.6g once, 3 times a day.

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Abstract

The invention relates to novel application of a pharmaceutical composition to preparing medicament for preventing and treating allergic diseases. The prescription consists of 66 portions of astragalus, 27 portions of red paeonia, 27 portions of Salviae miltiorrhiza radix, 27 portions of angelica, 27 portions of Szechuan lovage rhizome, 27 portions of peach kernel, 13 portions of safflower, 13 portions of prepared libanotus, 13 portions of prepared myrrh, 20 portions of caulis milletiae, 27 portions of achyranthis root, 20 portions of cassia twig, 27 portions of mulberry twig, 27 portions of earthworm, 13 portions of scorpion, and 27 portions of leech. Medicament forms comprise pill, granule, hard capsule, soft capsule, troche, dripping pill or oral liquid. The invention aims to provide novel treatment application of the pharmaceutical composition, which enlarges the clinical application range, and avoids waste of favorable medicament resource.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition in the preparation of medicines for preventing and treating type I allergic diseases. [0002] Background technique [0003] Allergy, also known as anaphylaxis, hypersensitivity, refers to the abnormal or pathological immune response that occurs when a body that has been sensitized by a certain antigen is stimulated again by the same antigen, which is manifested as physiological dysfunction or tissue cell damage. According to the mechanism of allergic reaction, it is usually divided into type IV. The first three types are mediated by antibodies, and type IV is mediated by cellular immunity. Clinically, two or three types of allergic reactions often coexist, with one being the main type. An antigen can cause different types of allergic reactions under different conditions. Type I has the highest incidence rate among all types of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/732A61K9/00A61K9/16A61K9/20A61K9/48A61P37/08A61P11/02A61P11/06A61P17/00A61P27/02A61K35/62A61K35/64A61K35/646
Inventor 赵涛
Owner SHANXI BUCHANG PHARMA CO LTD
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