New preparation method of Ozagrel sodium powder injection

A technology of sodium ozagrel and freeze-dried powder injection, which is applied in the directions of non-active ingredient medical preparations, medical preparations containing active ingredients, powder delivery, etc., and can solve unqualified clarity, inconvenience, side effects, etc. problems, to achieve the effect of convenient clinical use, small side effects, and good appearance.
CN101596167AInactive Publication Date: 2009-12-09HARBIN PHARMA GROUP BIOLOGICAL ENG

Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
HARBIN PHARMA GROUP BIOLOGICAL ENG
Publication Date
2009-12-09
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention researches a new preparation method by aiming at the problems of side effect and inconvenient use of the clinical application of an Ozagrel sodium refrigerated dry powder injection and applies polyglucose to the Ozagrel sodium refrigerated dry powder injection for the first time, the Ozagrel sodium refrigerated dry powder injection is decolorized by active carbon and filtered by a filter film with the aperture of 0.22 micrometer so as to solve the poor appearance problem of the Ozagrel sodium powder injection, achieve the purposes of convenient use, cost reduction, curative effect guarantee and side effect reduction and solve the problem of unqualified clarity generated by applying the polyglucose to the refrigerated dry injection.
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Description

technical field

[0001] The invention relates to a preparation method of a novel ozagrel sodium freeze-dried powder injection, in particular to a ozagrel sodium freeze-dried preparation containing condensed glucose as an excipient. Background technique

[0002] Sodium ozagrel can improve the hemorheology indicators of patients with cerebral infarction, reduce blood viscosity, accelerate thrombolysis, and improve movement disorders in patients. Years of clinical trials have proved that ozagrel is effective, safe, and has few side effects. It has a good curative effect in the treatment of acute cerebral infarction (improving neurological deficit), cerebral infarction and the movement disorders accompanying these diseases. It is a representative class of good antithrombotic drugs, with a clear pharmacological mechanism, a cure rate and marked effect of 75.5%, and a total effective rate of over 95%. The pharmacology, toxicology, pharmacodynamics, pharmacokinetics and pharmaceuti...

Claims

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