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Application of compound oriental smartweed preparation in preparing medicaments for preventing and treating diabetes mellitus and complicating diseases thereof

A technology for diabetes and diabetic nephropathy, which is applied in the application field of traditional Chinese medicine preparations, and can solve the problems of the prevention and treatment of diabetes by the compound radishes, and achieve good curative effect

Inactive Publication Date: 2012-03-21
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report on the clinical pharmacological research on the prevention and treatment of diabetes by using the compound radishes.

Method used

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  • Application of compound oriental smartweed preparation in preparing medicaments for preventing and treating diabetes mellitus and complicating diseases thereof
  • Application of compound oriental smartweed preparation in preparing medicaments for preventing and treating diabetes mellitus and complicating diseases thereof
  • Application of compound oriental smartweed preparation in preparing medicaments for preventing and treating diabetes mellitus and complicating diseases thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0091] Take 50kg of sage and add 10 times of water to decoct 3 times, each time for 1 hour, filter, combine the filtrate, concentrate under reduced pressure, add ethanol to make the alcohol content reach 65%, let it stand for 12 hours, filter with suction, and filter the supernatant , the filtrate was extracted 3 times with ethyl acetate, discarded the ethyl acetate solution, combined the aqueous layer, adjusted the pH value to 3 with hydrochloric acid, extracted 4 times with n-butanol saturated with water, combined the n-butanol solution, washed with water, and recovered under reduced pressure n-butanol, the residue was dissolved in 80% ethanol, put on a polyamide column (500g, Φ8cm, diameter-to-height ratio 1:6, adsorption flow rate 1.5BV / h), collected flow-through and eluent, recovered ethanol, residue Vacuum drying, to obtain the extract of Chinese radishes;

[0092] Take 10 kg of Asarum breviscapus and add 10 times of water to decoct 3 times, 0.5 hours each time, filter, ...

Embodiment 2

[0094]The Orientia officinalis extract obtained in Example 1 and the extract of Erigeron breviscapine were mixed, and an injection was prepared by conventional techniques of pharmacy.

Embodiment 3

[0096] The Orientia officinalis extract obtained in Example 1 and the extract of Erigeron breviscapine were mixed, and prepared into tablets by conventional techniques of pharmacy.

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Abstract

The invention relates to application of a compound oriental smartweed preparation in preparing medicaments for preventing and treating diabetes mellitus and complicating diseases thereof. The compound oriental smartweed preparation consists of oriental smartweed and Erigeron breviscapus.

Description

technical field [0001] The invention relates to an application of a traditional Chinese medicine preparation, in particular to an application of a compound radishes root preparation in the preparation of medicines for preventing and treating diabetes and its complications. technical background [0002] Diabetes Mellitus (DM) is a common endocrine and metabolic disorder and frequently-occurring disease. Prolonged illness can cause multi-system damage, leading to eye, kidney, nerve, heart, blood vessel and other diseases. With the aging of the population, the economic development of various countries and the change of people's lifestyle, the prevalence of diabetes is increasing rapidly around the world, seriously threatening human health. Currently, the number of DM patients worldwide has reached 150 million, and it is predicted to reach 300 million by 2025. In recent years, the prevalence of DM in my country has increased rapidly. In 2002, there were about 40 million DM pati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/704A61P3/10
Inventor 窦啟玲周黎亚
Owner GUIZHOU YIBAI PHARMA CO LTD
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