Medicinal composition for aerosol

A technology of composition and aerosol, which is applied in the field of pharmaceutical preparations, can solve problems such as rising costs and complicated processing technology, and achieve the effects of improving the ratio, simplifying the processing technology, and reducing costs

Active Publication Date: 2010-06-09
YANGTAI PHARMA SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The technical effects of this new formulation include reducing manufacturing expenses while maintaining consistently high levels of performance without harmful chemicals or causing health hazards during storage. It achieves these advantages through replacing expensive components like dichlormichloroform (CFC) instead ofFreons because they have excellent solvability properties and lower volatilities at room temperature. Additionally, there're fewer compounds involved due to their ability to dissolve easily into water. Overall, this new formula helps create safer products from drug discovery processes.

Problems solved by technology

Technological Problem addressed in this patents relating to fronthaflorescent materials includes their challenges with respect to prevention or reduction of global warming caused through greenhouse gas emissions. These technical problem being solved involves finding ways to replace existing products containing these compounds without causing negative effects upon our ecosystem.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A kind of methyl salicylate aerosol, its proportioning is: (weight percent)

[0018] Methyl Salicylate 0.5%

[0019] Absolute Ethanol 39.5%

[0020] HCFC-22 60%

[0021] Preparation method: Weigh the prescribed amount of methyl salicylate, add it to the prescribed amount of absolute ethanol, stir to mix evenly; fill the liquid medicine, and then press into the propellant.

Embodiment 2

[0023] A kind of diclofenac sodium aerosol, its proportioning is: (weight percentage)

[0024] Diclofenac Sodium 2%

[0025] Ethanol 30%

[0026] Propylene Glycol 2%

[0027] HCFC-22 66%

[0028] Preparation method: Weigh the prescribed amount of diclofenac sodium, add it to the prescribed amount of ethanol, then add the prescribed amount of propylene glycol, stir to mix evenly; fill the medicine liquid, and then press into the propellant.

Embodiment 3

[0030] A kind of lidocaine chlorhexidine acetate aerosol, its proportioning is: (weight percentage)

[0031] Lidocaine 2.00%

[0032] Chlorhexidine acetate 0.50%

[0033] Benzalkonium Bromide 0.10%

[0034] Isopropanol 2.70%

[0035] 95% ethanol 47.70%

[0036] HCFC-22 47.00%

[0037] Preparation method: heat and melt benzalkonium bromide; mix ethanol and isopropanol evenly, add lidocaine, chlorhexidine acetate, and benzalkonium bromide in the prescribed amount, stir to mix evenly; fill the liquid medicine, and then press into The propellant will do.

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PUM

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Abstract

The invention belongs to the technical field of medicaments and provides a medicinal composition which separately adopts difluorochloromethane without environmental destruction as a propellant. The medicinal composition not only substitutes dichlorodifluoromethane commonly called Freon 12 with environmental destruction which is often used in pharmaceutical production, but also avoids the problems of the increased cost and complicated processing technology brought by mixing various propellants. Due the adoption of the propellant for proportioning, the aerosol composition has the advantages of controllable pressure in a wide range, simple production technology, easy operation and capacity of completely meeting the requirement on the dichlorodifluoromethane substitute.

Description

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Claims

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Application Information

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Owner YANGTAI PHARMA SHANDONG
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