The invention provides a guided missile ground comprehensive test device and method based on a wireless network, and relates to the field of guided missile ground tests. The problems that full-automatic tests cannot be achieved through an existing guided missile test system and the test system is large in size, poor in portability, complex in test process, low in efficiency and the like are solved. The device is composed of a remote ground monitoring device and a ground automatic test device, wherein the two devices can be in communication through radios, and the communication distance can reach several kilometers. The remote ground monitoring device is used for sending a test instruction to the ground automatic test device and receiving test process data fed back by the ground automatic test device, and is used for data storage. The ground automatic test device automatically completes communication tests, self-inspection tests and the like according to the test instruction sent by the remote ground monitoring device. Compared with a traditional guided missile ground test system, the device has the beneficial effects of being small in size, small in weight, simple in test process, high in efficiency, short in guided missile test and launch time interval, safe to use, and the like.