Application of flavone lignan to preparing medicaments for treating virus B hepatitis

A technology for viral hepatitis and flavonoid lignan, applied in the field of medicine, can solve problems such as few documents, and achieve the effects of simple preparation steps, huge social and economic benefits, and high yield
CN101912384BInactive Publication Date: 2012-03-28DALI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DALI UNIV
Publication Date
2012-03-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to application of flavone lignan to preparing medicaments for treating virus B hepatitis, in particular to (+ / -)-2-[2,3-dihydro-3-(3,5-dimethoxy-4-hydroxyphenyl)-2-methylol-1,4-benzodioxane-6]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-ketone or application of medicinal salts thereof to preparing medicaments for treating the virus B hepatitis or preparing medicaments forreducing virus B hepatitis surface antigens (HBsAg). Because the flavone lignan has high-efficiency activity for suppressing the HBsAg, the flavone lignan can be expected to be applied to preparing medicaments for treating the virus B hepatitis.
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Description

technical field

[0001] The present invention relates to the technical field of medicine, specifically, the present invention relates to flavonoid lignans represented by formula (1) or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof in the preparation and treatment of hepatitis B virus infection diseases and anti-hepatitis B virus drugs use. The flavonoid lignan is found through pharmacodynamic tests to have a strong inhibitory effect on the activity of hepatitis B surface antigen HBsAg, and can be expected to be developed into an anti-hepatitis B virus drug. Background technique

[0002] Hepatitis B virus (hepatitis B for short) is an infectious disease caused by hepatitis B virus HBV, which is a member of the hepadnaviridae family of hepadnaviridae. HBV is a peculiar virus that is less contagious in other animals and can only replicate in humans or the primate chimpanzee. The virus is transmitted through blood and body fluids and has a ch...

Claims

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