Nano silver-carrying-silicon dioxide catheter and production method thereof

A silicon dioxide and nano-silver-loaded technology, applied in catheters and other directions, can solve the problems of intractable anti-infective drugs, drug resistance, and refractory infections

Inactive Publication Date: 2010-12-15
郭云童
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, because it is difficult for antibacterial drugs to enter the biofilm, even if a large amount of anti-infective drugs are used, it is difficult to cure them. Over time, drug resistance will develop and become a clinically refractory infection.
Because the current urinary catheter is made of silica gel or latex, it is very easy to produce bacteria on its surface, thereby causing complications. Therefore, the existing urinary catheter has the defect that it is easy to generate bacteria on its surface and cause complications

Method used

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  • Nano silver-carrying-silicon dioxide catheter and production method thereof
  • Nano silver-carrying-silicon dioxide catheter and production method thereof
  • Nano silver-carrying-silicon dioxide catheter and production method thereof

Examples

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Effect test

Embodiment 1

[0037] Such as Figure 12 Shown, the nano silver-loaded silicon dioxide (nanometer Ag-SiO 2 ) catheter, the catheter is made of nano silver-silica (nano Ag-SiO 2 ) made of antibacterial agent and silica gel, the ratio is to add nano silver-silicon dioxide (nanometer Ag-SiO 2 ) 0.05 gram of antibacterial agent.

[0038] This embodiment produces nanometer silver-loaded-silicon dioxide (nanometer Ag-SiO 2) a method for a urinary catheter, comprising the steps of:

[0039] 1) Making nano silver-loaded silicon dioxide (nano Ag-SiO 2 )Antibacterial agents

[0040] Weigh 5g of nano silicon dioxide (nanometer SiO 2 ) powder into 100ml of silver nitrate (AgNO 3 ) solution, adjust the pH value of the solution to keep it in the range of 6-8, and carry out the adsorption reaction under the dark condition of 50°C, and the reaction time is 4 hours; after the reaction, the reaction solution is centrifuged, and the The separated solid raw material is dissolved in deionized water and w...

Embodiment 2

[0048] Such as Figure 12 Shown, the nano silver-loaded silicon dioxide (nanometer Ag-SiO 2 ) catheter, the catheter is made of nano silver-silica (nano Ag-SiO 2 ) made of antibacterial agent and silica gel, the ratio is to add nano silver-silicon dioxide (nanometer Ag-SiO 2 ) 2 grams of antibacterial agent.

[0049] This embodiment produces nanometer silver-loaded-silicon dioxide (nanometer Ag-SiO 2 ) a method for a urinary catheter, comprising the steps of:

[0050] 1) Making nano silver-loaded silicon dioxide (nano Ag-SiO 2 )Antibacterial agents

[0051] Weigh 5g of nano silicon dioxide (nanometer SiO 2 ) powder into 100ml of silver nitrate (AgNO 3 ) solution, adjust the pH value of the solution to keep it in the range of 6-8, and carry out the adsorption reaction under the dark condition of 50°C, and the reaction time is 4 hours; after the reaction, the reaction solution is centrifuged, and the The separated solid raw material is dissolved in deionized water and wa...

Embodiment 3

[0059] Such as Figure 12 Shown, the nano silver-loaded silicon dioxide (nanometer Ag-SiO 2 ) catheter, the catheter is made of nano silver-silica (nano Ag-SiO 2 ) made of antibacterial agent and silica gel, the ratio is to add nano silver-silicon dioxide (nanometer Ag-SiO 2 ) 1 gram of antibacterial agent.

[0060] This embodiment produces nanometer silver-loaded-silicon dioxide (nanometer Ag-SiO 2 ) a method for a urinary catheter, comprising the steps of:

[0061] 1) Making nano silver-loaded silicon dioxide (nano Ag-SiO 2 )Antibacterial agents

[0062] Weigh 5g of nano silicon dioxide (nanometer SiO 2 ) powder into 100ml of silver nitrate (AgNO 3 ) solution, adjust the pH value of the solution to keep it in the range of 6-8, and carry out the adsorption reaction under the dark condition of 50°C, and the reaction time is 4 hours; after the reaction, the reaction solution is centrifuged, and the The separated solid raw material is dissolved in deionized water and was...

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Abstract

The invention relates to a nano silver-carrying-silicon dioxide catheter and a production method thereof, which belongs to a medical urethral catheterization device and the production method thereof. The invention mainly aims at solving the technical difficult problem that the existing catheter is easy to produce bacteria on the surface and further causes complications. The technical scheme of the invention is as follows: the nano silver-carrying-silicon dioxide catheter is prepared by a nano silver-carrying-silicon dioxide antibacterial agent and silica gel or latex, and the mixture ratio is that nano-silver-carrying-silicon dioxide is added in each 100ml of the silica gel or the latex. The method for producing the nano silver-carrying-silicon dioxide catheter comprises the following steps: 1) producing the nano silver-carrying-silicon dioxide antibacterial agent; and 2) producing the catheter: A) material preparation: firstly weighing raw materials according to the mixture ratio of adding 0.05-2g of the nano silver-carrying-silicon dioxide antibacterial agent into each 100ml of the silica gel or the latex, then pouring into a stirring machine for uniformly stirring, and monitoring the viscosity; B) impregnation; C) plasticization; D) lip curling, powdering and demolding; and E) removing powder, and finally carrying out inspection and packaging.

Description

technical field [0001] The present invention relates to a kind of nano silver-loaded silicon dioxide (nanometer Ag-SiO 2 ) a urinary catheter and a production method thereof, which belong to a medical catheterization device and a production method thereof. Background technique [0002] As a commonly used implant in urology, urinary catheter is widely used in clinical practice. Catheter-associated urinary tract infections (CAUTIs) are a common complication of indwelling catheters. When the catheter is implanted in the body, bacteria will form a layer of biofilm (BBF) on the surface of the catheter as the indwelling time prolongs. The bacteria present in the biofilm will cause urinary tract infection in patients through a special drug resistance mechanism and slow release. The repeated infection of the system and even the whole body will not heal for a long time. At the same time, because it is difficult for antibacterial drugs to enter the biofilm, it is difficult to cure ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/04A61L29/02A61L29/16A61M25/00
Inventor 刘春郭云童边海龙翟军红魏丽乔
Owner 郭云童
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