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Melamine hapten, melamine complete antigen and preparation method thereof

A technology of melamine and complete antigen, applied in chemical instruments and methods, animal/human protein, serum albumin, etc., can solve problems such as high nitrogen content, falsely high protein content, people's health and life hazards, and achieve high sensitivity , good effect of specificity

Inactive Publication Date: 2011-01-26
INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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Problems solved by technology

However, because of its high nitrogen content, adding it to food can produce the false appearance of high protein content, so it was illegally added to milk and other protein products, which led to the "Sanlu milk powder incident" that shocked the world in 2008 and its predecessors. Serious food safety accidents such as the melamine poisoning incident of pets in the United States in 2007 have caused great harm to people's health and lives

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  • Melamine hapten, melamine complete antigen and preparation method thereof
  • Melamine hapten, melamine complete antigen and preparation method thereof
  • Melamine hapten, melamine complete antigen and preparation method thereof

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Abstract

The invention discloses a melamine hapten, a melamine complete antigen and a preparation method thereof, wherein, the melamine complete antigen has a structure as follows: the complete antigen can maintain better physicochemical properties of the original compound such as a chemical structure, charge distribution, a space structure and the like and obtain an antibody with good specificity and high sensitivity while immunizing an experimental animal, thus laying a foundation for subsequent establishment of a rapid, sensitive and efficient ELISA melamine detection method.

Description

technical field The invention relates to a melamine hapten, a melamine complete antigen, a preparation method of the melamine hapten and a preparation method of the melamine complete antigen. Background technique The people take food as their heaven and food safety as their first priority, and food safety is related to the health and safety of the people. However, the Sanlu milk powder incident in 2008 caused 300,000 children in China to suffer from diseases, and at least 6 babies died, which broke the hearts of countless families. After the incident, China issued a notice on the provisional management limit value of melamine in dairy products and foods containing milk. However, incidents of illegally adding melamine have been repeatedly banned. Afterwards, it was reported that in December 2009, Shanghai Panda and Shaanxi Jinqiao Dairy milk powder was found to have exceeded the standard of melamine; Lekang Dairy melamine case was detected and melamine-exceeding milk powder...

Claims

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Application Information

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IPC IPC(8): C07D251/52C07K14/765C07K14/77C07K14/795
Inventor 高志贤凌华浓周青青陈超柳明宁保安
Owner INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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