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Plant antibiotic

A plant antibiotic and filtrate technology, applied in the field of medicine, to achieve the effects of clear ingredients, repair of diseased tissue, extensive use value and development prospects

Active Publication Date: 2012-12-26
方东艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report on the preparation of plant antibiotics by traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: prepare plant antibiotic of the present invention

[0029]Accurately weigh (in kg) pumpkin seeds 7.00, rapeseed 8.50, papaya seeds 5.50, grapefruit 6.50, sweet orange 8.00, mung bean 8.00, gardenia 9.00, guava 8.50, black sesame 9.50, pine needle 9.50, Magnolia 3.50 , Raw hawthorn 5.00, Su Ye 5.00, Huoxiang 3.50kg and ethanol 25.00kg soaked for 3 days, filtered after 3 days to obtain ethanol liquid. Add 40kg of distilled water to the medicinal residues, decoct for 4 hours, and filter to obtain 35kg of a decoction liquid. Add 20kg of distilled water to the first decoction residue, decoct for 3 hours, filter to obtain 15kg of the second decoction liquid, mix the ethanol liquid with the first and second decoction liquids, let stand for 3 days, and filter to obtain 95kg of the liquid. The filtered medicinal liquid was added to the ethanol distillation kettle for distillation, vacuum concentrated at 60°C-70°C to remove ethanol, kept at a constant temperature f...

Embodiment 2

[0030] Example 2: Preparation of plant antibiotics of the present invention

[0031] Accurately weigh (in kg) pumpkin seeds 5.50, rapeseed 7.50, papaya seeds 3.80, grapefruit 7.00, sweet orange 7.50, mung bean 7.80, gardenia 8.00, guava 7.80, black sesame 7.50, pine needle 8.50, Magnolia 3.80 , Raw Hawthorn 5.30, Su Ye 4.80, Huoxiang 3.20kg, add 22.00kg of ethanol, soak for 3 days, filter after 3 days to obtain ethanol liquid. Add 40kg of distilled water to the medicinal residues, decoct for 4 hours, and filter to obtain 35kg of a decoction liquid. Add 20kg of distilled water to the first decoction residue, decoct for 3 hours, filter to obtain 15kg of the second decoction liquid, mix the ethanol liquid with the first and second decoction liquids, let stand for 3 days, and filter to obtain 95kg. The filtered medicinal liquid was added to the ethanol distillation kettle for distillation, vacuum concentrated at 60°C-70°C to remove ethanol, kept at a constant temperature for 3 ho...

Embodiment 3

[0032] Example 3: Preparation of plant antibiotics of the present invention

[0033] Accurately weigh (in kg) pumpkin seeds 5.00, rapeseed 6.50, papaya seeds 3.80, grapefruit 7.00, sweet orange 7.00, mung bean 7.50, gardenia 6.00, guava 7.20, black sesame 5.50, pine needle 7.50, Magnolia 4.00 , Raw hawthorn 5.50, Su Ye 4.50, Huoxiang 3.00kg and ethanol 20.00kg soaked for 3 days, filtered after 3 days to obtain ethanol liquid. Add 40kg of distilled water to the medicinal residues, decoct for 4 hours, and filter to obtain 35kg of a decoction liquid. Add 20kg of distilled water to the first decoction residue, decoct for 3 hours, filter to obtain 15kg of the second decoction liquid, mix the ethanol liquid with the first and second decoction liquids, let stand for 3 days, and filter to obtain 95kg of the liquid. The filtered medicinal liquid was added to the ethanol distillation kettle for distillation, vacuum concentrated at 60°C-70°C to remove ethanol, kept at a constant tempera...

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Abstract

The invention discloses a plant antibiotic which is prepared by the following steps of soaking pumpkin seeds, pawpaw seeds, grapefruits, sweet oranges, mung beans, gardenia, guava, black sesames, Mangnolia officinalis, raw hawthorns, caulis perllae, pine needles and wrinkled gianthyssop herb in ethanol according to a certain ratio, carrying out low-temperature distillation, vacuum concentration and extraction. The acid containing content of the plant antibiotic is not less than 0.4% (measured by chlorogenic acid), and the phenol containing content is not less than 4.18% (measured by guaiacol). The pH value is 2.0 to 4. The invention has the advantages of wide antimicrobial spectrum, obvious inactivation effect on virus, fungi and bacteria, safety and stability as well as wide application prospect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a plant antibiotic. Background technique [0002] Antibiotics are a class of secondary metabolites with anti-pathogen or other activities produced by microorganisms including bacteria, fungi, actinomycetes or higher animals and plants in the course of life, chemical substances that can interfere with other cell development functions . The commonly used antibiotics in clinical practice are extracts from microbial culture fluid and chemically synthesized or semi-synthesized compounds. [0003] The current abuse of antibiotics has produced some social problems. The overuse of antibiotics causes bacteria to gradually produce drug-resistant genes, making antibiotics less effective or even ineffective. Moreover, bacterial resistance can be transmitted to each other, complicating bacterial resistance. In addition, excessive use of antibiotics will kill a large number of normal bacteria in th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K8/97A61Q11/00A61P1/02A61P27/16A61P31/04A61P31/10A61P31/12A61P37/04
Inventor 王贵林
Owner 方东艳
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