Medicine eluting balloon catheter

Abstract

The invention provides a medicine eluting balloon catheter, which comprises a balloon catheter body and a medicine coating, wherein the balloon catheter body comprises a balloon; the outside surface of the balloon has a plurality of grooves; and the medicine coating is coated on the grooved part and flat part of the outside surface of the balloon. The medicine eluting balloon catheter is characterized in that grooves protrude in a reversed direction when the balloon is fully expanded. The medicine eluting balloon catheter disclosed by the invention can carry more medicines and reduce loss of the medicines in a conveying process; and the medicine eluting balloon catheter directly pour and cast medicines remaining in the grooves into blood through reversed protrusion to accelerate the release of the medicines and to increase the medicine concentration at a target position, so that the medicines can quickly concentrate and act on the target position to well prevent the blood vessel tissue at the target position from regeneration and restenosis.

Description

technical field [0001] The invention relates to the field of medical instruments. More specifically, the present invention relates to a drug eluting balloon catheter. Background technique [0002] Since the 1970s, intraluminal balloon angioplasty has been widely used in the treatment of vascular stenosis caused by atherosclerosis. Although the immediate therapeutic effect of balloon angioplasty is satisfactory, the high incidence of surgical complications, especially restenosis, limits its wide application in clinic. Intravascular stenting is the implantation of a stent in the stenotic area while the balloon is inflated. The stent resists the restenosis caused by vascular delamination and elastic recoil, and can significantly reduce the acute or subacute ischemic complications of interventional therapy. However, the placement of stents stimulates the migration and proliferation of vascular smooth muscle cells, causing intimal hyperplasia and in-stent restenosis. [0003] ...

AI Technical Summary

Problems solved by technology

The amount of drug that can be loaded on the flat outer surface of the balloon is limited, not only will a large amount of drug be lost due to contact with the blood vessel wall and blood during delivery, but also the drug release rate is slow

Although there are also technicians who have proposed a drug-eluting balloon catheter with a concave-convex non-flat structure for the purpose of increasing the drug loading (see the invention patent application "Drug Balloon Catheter and Its Preparation Method" with the patent application number 201010121627.4), but , this kind of concave-convex non-flat structure is rigid and thick. Although it can increase the drug loading and reduce the loss during delivery by holding the drug in the concave part, after being delivered to the target position, the concave part, especially the deep part of the concave part, remains The drug is less likely to be released rapidly outwards, so that the drug release cannot be accelerated well

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