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Dentifrice composition

A composition and dentifrice technology, applied in the directions of drug combination, medical science, dentistry, etc., can solve the problems of poor use feeling, increased stringiness, sticky feeling, etc., and achieve improved use feeling, improved retention, The effect of suppressing stickiness

Active Publication Date: 2012-07-11
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these moisturizers have a problem of poor usability due to their high viscosity, which increases stringiness and creates a sticky feeling depending on the amount of blending.
[0011] In this way, isopropylmethylphenol is useful as a bactericidal component of a dentifrice composition due to its excellent permeability to oral biofilms, but mixing isopropylmethylphenol into a dentifrice composition does not impair the feeling of use. , make it satisfactorily stay in the oral cavity, and exert a high biofilm bactericidal effect, which are difficult and difficult to be practical for the existing technology

Method used

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  • Dentifrice composition
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Examples

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Embodiment

[0081] Hereinafter, the present invention will be described in detail with examples and comparative examples, but the present invention is not limited by the following examples. In addition, in the following examples, unless otherwise stated, % means mass %.

[0082] [Example, Comparative Example]

[0083] The dentifrice composition (toothpaste) of the composition shown in Tables 3-5 was prepared according to the following manufacturing method.

[0084] (Manufacturing method)

[0085] (1) Mix and dissolve water-soluble ingredients (except binder and propylene glycol) in pure water at room temperature to prepare Phase A.

[0086] (2) Prepare phase B in which the binder is dispersed in propylene glycol at room temperature.

[0087] (3) Add phase B to phase A while stirring, and mix to prepare phase C.

[0088] (4) Use a 1.5L kneader (manufactured by Ishiyama Works) to mix ingredients other than water-soluble ingredients such as fragrances and abrasives into phase C at room t...

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Abstract

Disclosed is a dentifrice composition which exhibits high local retention properties for a preparation in the oral cavity, while having an excellent bactericidal effect on oral biofilms. The dentifrice composition has a flavor that is almost free from unpleasant taste and excellent feeling of use, while being suppressed in stickiness. Specifically disclosed is a dentifrice composition which is characterized by containing (A) isopropyl methyl phenol, (B) at least one fragrance material selected from among 3-octanol, 3-octyl acetate, 3-octanone and fenchone, (C) sorbit, (D) glycerin and (E) a polyethylene glycol that has an average molecular weight of 280-9,300. The dentifrice composition additionally contains (F) anisaldehyde.

Description

technical field [0001] The present invention relates to a dentifrice composition having a high retention property in the oral cavity, excellent oral biofilm sterilizing power, less odor, less sticky feeling, and excellent usability. Background technique [0002] It is generally believed that the two major oral diseases, dental caries and periodontal disease, are caused by various bacteria in the biofilm in the oral cavity. In particular, dental caries is an infection caused by streptococci such as Streptococcus mutans (S.mutans), and periodontal disease is an infection mainly caused by obligate anaerobic Gram-negative bacteria such as Porphyromonas gingivalis (P.gingivalis) In addition, the cause of bad breath is related to oral bacteria such as Fusobacterium nucleatum (F.nucleatum). Therefore, it is said that keeping the number of pathogenic bacteria in the biofilm in the oral cavity at a low level is useful as an effective means for preventing and improving oral diseases....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/35A61K8/37A61K8/39A61K8/86A61Q11/00
CPCA61K2800/592A61K8/33A61Q11/00A61K8/345A61K8/86A61K8/347A61P1/02
Inventor 山本幸司平山隆天野步
Owner LION CORP
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