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Medicine composition used for controlling poultry airsacculitis, and preparation method thereof

A composition and a technology for airsacculitis, applied in the field of veterinary drug compositions, can solve the problems of reducing the curative effect of antibacterial drugs, preventing and treating the impact of diseases, and comprehensive prevention and treatment of avian airsacculitis without effective medicines, so as to achieve synergistic immunity, maintain smooth breathing, The effect of controlling bacterial secondary infection

Active Publication Date: 2013-10-16
NANJING AGRICULTURAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, isopamicin and tigecycline are non-animal-specific antibacterial drugs, and excessive use of human drugs in veterinary clinics can easily induce bacterial resistance and reduce the efficacy of antibacterial drugs. Drugs to prevent disease have very bad effects
It can be seen from the above that there is no effective drug for comprehensive prevention and treatment of poultry air sacs caused by different pathogenic bacteria

Method used

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  • Medicine composition used for controlling poultry airsacculitis, and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 The present invention is used for the preparation of the pharmaceutical composition of poultry air sacculitis prevention and treatment

[0025] Proceed as follows:

[0026] (1) Weigh 200 g of tercetin (Yichang Xiangrong Chemical Co., Ltd., the same below), doxycycline (Beijing Boyahua Animal Husbandry Technology Co., Ltd., the same below) 300 g, colistin sulfate (Shandong Victory Co., Ltd. , the same below) 300g, levamisole (Zhengzhou Rongsheng Animal Pharmaceutical Co., Ltd., the same below) 100g, vitamin C (Beijing Boyahua Animal Husbandry Technology Co., Ltd., the same below) 600g, oral glucose (Weifang Tianhao Animal Pharmaceutical Co., Ltd. Co., Ltd.) 500g, dried, pulverized, and passed through a 60-mesh sieve.

[0027] (2) Mix teretin, doxycycline, colistin sulfate, levamisole and vitamin C uniformly to obtain mixture A.

[0028] (3) Mix 500 g of oral glucose and 200 mg of dexamethasone uniformly to obtain mixture B.

[0029] (4) Mix mixture A and ...

Embodiment 2

[0030] Embodiment 2 The present invention is used for the preparation of the pharmaceutical composition of poultry air sacculitis prevention and treatment

[0031] Proceed as follows:

[0032] (1) Weigh 300g of teretin B, 400g of doxycycline, 400g of colistin sulfate, 60g of levamisole, 400g of vitamin C, 440g of anhydrous glucose (Weifang Tianhao Animal Pharmaceutical Co., Ltd.), dry, pulverize, pass 60 Mesh sieve.

[0033] (2) Mix teretin, doxycycline, colistin sulfate, levamisole and vitamin C uniformly to obtain mixture A.

[0034] (3) Mix 440 g of anhydrous glucose and 200 mg of dexamethasone uniformly to obtain mixture B.

[0035] (4) Mix mixture A and mixture B evenly, and pass through an 80-mesh sieve to obtain the soluble powder of the pharmaceutical composition of the present invention. Packed separately, 100g / bag.

Embodiment 3

[0036] Embodiment 3 The present invention is used for the preparation of the pharmaceutical composition of poultry air sacculitis prevention and treatment

[0037] Proceed as follows:

[0038] (1) Weigh 400g of teretin B, 200g of doxycycline, 200g of colistin sulfate, 40g of levamisole, 200g of vitamin C, 960g of Fumei powder (Zhengzhou Xinyuan Biotechnology Co., Ltd.), dry, pulverize, and pass through 60 mesh screen;

[0039] (2) Mix teretin, doxycycline, colistin sulfate, levamisole and vitamin C uniformly to obtain mixture A.

[0040] (3) Mix 960 g of Fumei powder and 300 mg of dexamethasone evenly to obtain mixture B.

[0041] (4) Mix mixture A and mixture B evenly, and pass through an 80-mesh sieve to obtain the soluble powder of the pharmaceutical composition of the present invention. Packed separately, 100g / bag.

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Abstract

The invention belongs to the field of veterinary drugs, and discloses a medicine composition used for controlling poultry airsacculitis. The composition is composed of the components of, by weight: 10-20% of aesculetin, 10-20% of deoxycycline, 10-20% of colistine sulfate, 2-5% of levamisole, 10-30% of vitamin C, 0.01-0.015% of dexamethasone, and balance of auxiliary materials. The invention also provides a preparation method of the medicine composition. The medicine composition provided by the invention has high effect against poultry airsacculitis, wherein an effective rate can be higher than 95%. The medicine composition is also advantaged in fast effect. In a first day of medication, a substantial effect can be provided, and the disease can be cured in 4 days. Also, the medicine composition has a wide antimicrobial spectrum. The medicine composition has excellent killing effects against poultry airsacculitis pathogens such as Escherichia coli, mycoplasma, pseudomonas aeruginosa, and the like. The medicine composition can effectively control secondary bacterial infections. Further, the medicine composition provided by the invention is advantaged in simple production method and convenient application. The production method is labor-saving.

Description

technical field [0001] The invention belongs to the field of veterinary drug compositions, in particular to a pharmaceutical composition for preventing and treating poultry air sacculitis and a preparation method of the pharmaceutical composition. Background technique [0002] In recent years, with the rapid development of the poultry industry, air sacculitis has become more and more complicated, especially in areas where broiler chickens are intensively raised, and the phenomenon of mixed infection and secondary infection has become more and more serious. Amoy rate is very high. Symptoms of sick chickens include depression, dyspnea, rales, and cough. Autopsy shows that the air sacs are turbid, with a large amount of turbid exudate, thickened air sac walls, and cheese-like clots of various sizes. [0003] The unique structure of poultry air sacs, drug resistance and absorption problems to most drugs, and the clinical diagnosis and drug use level of veterinarians have made i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/12A61K31/65A61K31/429A61K31/375A61K31/573A61K31/366
Inventor 江善祥彭麟季辉张军忍万荣峰蔡冬刘利锋施宗傲张浩匡晓辰
Owner NANJING AGRICULTURAL UNIVERSITY
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