Preparation method and quality control method for schefflera kwangsiensis general flavone extract

Abstract

The invention discloses a preparation method and a quality control method for schefflera kwangsiensis general flavone extract. The preparation technology for the extract comprises the steps as follows: soaking a schefflera kwangsiensis medicinal material for 0.5 h by adding 8 to 10 times of ethanol by weight, wherein the volume concentration of the ethanol is from 60% to 80%; refluxing and extracting for 2 to 3 times with each time of 1 to 3 h; filtering and mixing filtrate; and decompressing and concentrating the filtrate at the temperature of 75 to 85 DEG.C to the temperature of 60 DEG.C, so as to obtain the extract with relative density of 1.10 to 1.30. The product quality control method mainly adopts a high performance liquid chromatography to detect the content of rutin. The preparation technology provided by the invention has the advantages of stable process parameter, process condition and process technology, high rutin extracting yield and strong industrial applicability. The quality control method provided by the invention has the advantages of high degree of separation, good linear relation, convenience, rapidness, accuracy and stability. Therefore, the quality control method meets the requirements of industrial production, and effectively controls the quality of the schefflera kwangsiensis general flavone extract and a preparation thereof.

Description

technical field [0001] The invention relates to a preparation method of Chinese peach leaf total flavonoid extract and a product quality control method. Background technique [0002] Chinese peach leaves are the tender stems and leaves of Schefflera kwangsiensis Merr. Ex L, a plant of the genus Schefflera in Araliaceae. Widely distributed in Guangxi, Guangdong, Fujian and other areas south of the Yangtze River, the main chemical and active ingredients of Chinese peach leaves are total flavonoids, mainly containing quercetin and rutin. Oral preparations such as tablets, capsules, dripping pills, and granules made from the total flavonoid extract have quick onset and long-lasting effects. [0003] The national pharmacopoeia standard of Chinese peach leaf (2010 edition one) records the preparation and content determination method of the total flavonoid extract, but the process parameters, process conditions and process technology of the preparation method are unreasonable, the...

AI Technical Summary

Problems solved by technology

[0003] The national pharmacopoeia standard of Chinese peach leaf (2010 edition one) records the preparation and content determination method of the total flavonoid extract, but the process parameters, process conditions and process technology of the preparation method are unreasonable, the extraction yield is low, and the content determination method Determination of the content of total flavonoids by ultraviolet-visible spectrophotometry, the operation is cumbersome, the stability is poor, and the error is large

Therefore, the current preparation and content control methods of Chinese peach leaves cannot be well adapted to the needs of industrial production, and the product quality is difficult to be effectively controlled