Method for acquiring characterization parameters of hypertension and complication

A technology of characterization parameters and acquisition methods, applied in the field of medical testing, can solve the problem of comprehensive genetic analysis of susceptibility to complex diseases, comprehensive genetic analysis of susceptibility to hypertension and complications, lack of in-depth research, lack of accuracy, and systematic and comprehensiveness to achieve efficient integration

Active Publication Date: 2013-07-31
西安时代基因健康科技股份有限公司
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Problems solved by technology

[0007] At present, related patents on the early warning or intervention of hypertension and complications focus on the diagnosis and post-treatment evaluation of a single disease, and there are few reports on the comprehensive genetic analysis method for the susceptibility of a single SNP locus in complex diseases
At the same time, there are not many in-depth studies on the comprehensive genetic analysis of the susceptibility to hypertension and complications, and the early warning or intervention products for the transformation of the genetic health industry simply "copy" the health management recommendations of European and American countries, which lack accuracy, system and comprehensiveness

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  • Method for acquiring characterization parameters of hypertension and complication

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Embodiment Construction

[0040] The present invention provides a method for obtaining the characterization parameters of hypertension and complications, the method for obtaining the characterization parameters of hypertension and complications comprises the following steps:

[0041] 1) Establish a database of susceptibility genes for hypertension and complications:

[0042] 1.1) The names of genes associated with hypertension were preliminarily found on the GWAS website;

[0043] 1.2) In the Pubmed database of NCBI, the susceptibility genes related to Chinese hypertension were screened out;

[0044] 1.3) Find the results of the association analysis related to the Chinese population, and determine the locus of the susceptibility gene obtained in step 1.2); the conditions to be met for the association analysis related to the Chinese population are: the sample is a large sample population, and the source of the sample is Chinese population, OR value greater than 1, 95% CI does not include 1, and statist...

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Abstract

The invention relates to a method for acquiring characterization parameters of hypertension and complication. The method comprises the following steps of: 1) establishing a hypertension and complication susceptibility gene database; 2) constructing an individual hypertension and complication characterization parameter analysis platform according to the hypertension and complication susceptibility gene database established in the step (1); 3) analyzing individual hypertension and complication characterization parameters based on the analysis platform constructed in the step (2); and 4) outputting individual hypertension and complication characterization parameters. The invention provides a method for acquiring the hypertension and complication characterization parameters which can acquire accurate characterization information, can acquire the information timely and can lay a foundation for follow-up treatment work.

Description

technical field [0001] The invention belongs to the technical field of medical detection and relates to a method for acquiring parameters, in particular to a method for acquiring characteristic parameters of hypertension and complications. Background technique [0002] Primary hypertension is a syndrome in which elevated blood pressure is the main clinical manifestation with or without multiple cardiovascular risk factors, usually referred to simply as hypertension. Hypertension is an important cause and risk factor of various cardiovascular and cerebrovascular diseases. It affects the structure and function of important organs, such as the heart, brain, and kidneys, and eventually leads to the failure of these organs. It is still the main cause of death from cardiovascular diseases. one of the reasons. [0003] The 2010 edition of the "Guidelines for the Prevention and Treatment of Hypertension in China" announced that there are currently more than 200 million hypertensive...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00
Inventor 杨进董靖徐博特贺红娟蔡丹张伟许嘉玲李林赵东
Owner 西安时代基因健康科技股份有限公司
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