Traditional Chinese medicine composition with antitumor effect and preparation method of injection thereof

An anti-tumor effect and composition technology, applied in the field of medicine, can solve problems such as drug resistance, body damage, and obvious toxic and side effects, and achieve the effects of prolonging survival, improving clinical symptoms and signs, and having no toxic and side effects

Inactive Publication Date: 2015-08-05
XIAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a traditional Chinese medicine composition with anti-tumor effect, which solves the problem of interruption of treatment due to large damage to the body, obvious toxic and side effects caused by surgery, radiotherapy and chemotherapy of Western medicine, and long-term chemotherapy in the existing tumor treatment process. It also avoids the potential danger of promoting tumor spread or metastasis by using traditional Chinese medicines of promoting blood circulation and removing blood stasis, especially "breaking blood"

Method used

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  • Traditional Chinese medicine composition with antitumor effect and preparation method of injection thereof
  • Traditional Chinese medicine composition with antitumor effect and preparation method of injection thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0025] Step 1: Weigh 1500g (43.48%) of tiankui seeds, 750g (21.74%) of nightshade, 750g (21.74%) of cat's claw, 300g (8.69%) of agrimony, and 150g (4.35%) of rhodiola rosea, mix, Add 8 times the quality of purified water, soak for 15 minutes, decoct and extract for 120 minutes, separate the liquid medicine and medicinal residues; add 8 times the quality of purified water to the medicinal residues, decoct and extract twice, 45 minutes each time, separate the medicine liquid, discard the dregs; combine the 3 extractions, concentrate under reduced pressure to a clear paste (1.5-2.5g per milliliter is equivalent to the original medicinal material), put it at room temperature, add ethanol with a mass concentration of 95% to make the alcohol content reach 60 %, refrigerated at 2-5°C for 48 hours, filtered to remove the precipitate; the filtrate was decompressed to recover ethanol until it had no alcohol smell, added 400ml of 5% gelatin solution, stirred while adding until no precipit...

Embodiment 2

[0028] Step 1: Weigh 450g of geranium seeds (7.56%), 1500g of nightshade (25.21%), 1500g of cat's claw (25.21%), 1500g of agrimony (25.21%), and 1000g of rhodiola rosea (16.81%), mix, Add 12 times the quality of purified water, soak for 60 minutes, decoct and extract for 90 minutes, separate the medicinal liquid and medicinal residues; add 10 times the quality of purified water to the medicinal residues, decoct and extract twice, 60 minutes each time, separate the medicinal liquid, discard the dregs; combine the 3 extracts, concentrate under reduced pressure to a clear paste (1.5-2.5g per milliliter is equivalent to the original medicinal material), put it at room temperature, add ethanol with a mass concentration of 95% to make the alcohol content reach 65 %, refrigerated at 2-5°C for 36 hours, filtered to remove the precipitate; the filtrate was decompressed to recover ethanol until it had no alcohol smell, added 450ml of 5% gelatin solution, stirred while adding until no pre...

Embodiment 3

[0031] Step 1: Weigh 1500g (24.00%) of geranium seed, 750g (12.00%) of nightshade, 1500g (24.00%) of cat's claw, 1500g (24.00%) of agrimony, 1000g (16.00%) of rhodiola rosea, mix, Add 15 times the quality of purified water, soak for 90 minutes, decoct and extract for 30 minutes, separate the medicinal liquid and medicinal residues; add 12 times the quality of purified water to the medicinal residues, decoct and extract twice, 30 minutes each time, separate the medicinal liquid, discard the dregs; combine the 3 extracts, concentrate under reduced pressure to a clear paste (1.5-2.5g per milliliter is equivalent to the original medicinal material), put it at room temperature, add ethanol with a mass concentration of 95% to make the alcohol content reach 70 %, refrigerated at 2-5°C for 24 hours, filtered to remove the precipitate; the filtrate was decompressed to recover ethanol until it had no alcohol smell, added 500ml of 5% gelatin solution, stirred while adding until no precipi...

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Abstract

The invention relates to a traditional Chinese medicine composite with anti-tumor effect and a preparation method of an injection of the same. The traditional Chinese medicine composite comprises the following components in percentage by weight: 7.56%-43.48% of radix semiaquilegiae, 12.00%-47.62% of solanum nigrum, 12.00%-47.62% of radix ranunculi ternati, 5.17%-42.67% of hairyvein agrimony and 2.44%-30.77% of rhodiola sachalinensis, wherein the sum of the weight percentage of the components is 100%. The preparation method comprises the following steps of: weighing materials; extracting, and refining; embedding; sterilizing. The traditional Chinese medicine composite disclosed by the invention keeps the characteristic of the integrated action of multiple component, multiple target point and multiple effects of Chinese herbal medicines, inhibits the tumor cell and prevents the diffusion transfer of the tumor cell through multiple action mechanisms, can not generate the drug resistance in a using process, can improve the symptoms and the physical signs, enhance the survival quality and prolong the survival time and is a Chinese herbal medicine anti-tumor formulation with wide application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine composition with antitumor effect, and also relates to a preparation method of the traditional Chinese medicine composition injection. Background technique [0002] Malignant tumors are major malignant diseases that seriously threaten human life and health. According to a survey by the Ministry of Health of China, malignant tumors have become the leading cause of death for urban and rural residents in my country. With the deterioration of the ecological environment and the increasingly prominent problems of food pollution, the incidence of malignant tumors has soared year by year in recent years, and it has become a worldwide intractable disease with a high mortality rate. At present, the main treatment methods for malignant tumors are surgery, radiotherapy and chemotherapy. Although surgical treatment can directly remove tumor lesions, it damages th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/81A61K9/08A61P35/00
Inventor 李伟泽周永强赵宁韩文霞
Owner XIAN MEDICAL UNIV
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