Preparation method of Jinma Gantai preparation for treating hepatitis

A technology for Jinmagantai and preparations, which is applied in the field of preparation of Jinmagantai preparations, can solve the problems of simple and rough methods, affecting the curative effect, and low content of active ingredients.

Active Publication Date: 2014-01-08
明远药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing products adopt the process recorded in WS-10313(ZD-0313)-2002-2012Z, the method is ...

Method used

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  • Preparation method of Jinma Gantai preparation for treating hepatitis
  • Preparation method of Jinma Gantai preparation for treating hepatitis
  • Preparation method of Jinma Gantai preparation for treating hepatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: 288.2g of horseshoe gold, 153.3g of iron clad gold, 115g of verbena, 191.6g of Fangji, 115g of Patrinia, 153.3g of Epimedium, 153.3g of Astragalus, 153.3g of Radix Paeoniae Rubra, 230g of Salvia miltiorrhiza

[0033] Add the above nine medicinal materials, add 6 times of water and decoct twice, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.14-1.16 (70-75°C), cool to room temperature, add Extract twice with the same amount of n-butanol, combine the n-butanol solution, add hydrochloric acid to the water solution to adjust the pH to 3-4, add the same amount of n-butanol to extract twice, combine the n-butanol solution, and adjust the pH of the water solution to 9 with ammonia water ~10, add the same amount of n-butanol to extract twice, combine all the n-butanol liquids, recover the solvent under reduced pressure to a thick paste with a relative density of 1.34~1.40 (50~60°C), add 4 ...

Embodiment 2

[0034] Example 2: 288.2g of horseshoe gold, 153.3g of iron-coated gold, 115g of verbena, 191.6g of Fangji, 115g of Patrinia, 153.3g of Epimedium, 153.3g of Astragalus, 153.3g of Radix Paeoniae Rubra, 230g of Salvia miltiorrhiza

[0035]Add the above nine medicinal materials, add 6 times of water and decoct twice, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.14-1.16 (70-75°C), cool to room temperature, add Extract twice with the same amount of n-butanol, combine the n-butanol solution, add hydrochloric acid to the water solution to adjust the pH to 3-4, add the same amount of n-butanol to extract twice, combine the n-butanol solution, and adjust the pH of the water solution to 9 with ammonia water ~10, add the same amount of n-butanol to extract twice, combine all n-butanol liquids, recover the solvent under reduced pressure to a thick paste with a relative density of 1.34~1.40 (50~60°C), dry under...

Embodiment 3

[0036] Example 3: 288.2g of horseshoe gold, 153.3g of iron-coated gold, 115g of verbena, 191.6g of Fangji, 115g of Patrinia, 153.3g of Epimedium, 153.3g of Radix Astragali, 153.3g of Radix Paeoniae Rubra, 230g of Salvia miltiorrhiza

[0037] Add the above nine medicinal materials, add 6 times of water and decoct twice, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.14-1.16 (70-75°C), cool to room temperature, add Extract twice with the same amount of n-butanol, combine the n-butanol solution, add hydrochloric acid to the water solution to adjust the pH to 3-4, add the same amount of n-butanol to extract twice, combine the n-butanol solution, and adjust the pH of the water solution to 9 with ammonia water ~10, adding an equal amount of n-butanol for extraction twice, combining all the n-butanol liquids, recovering the solvent under reduced pressure to a thick paste with a relative density of 1.34~1.4...

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Abstract

The invention relates to a preparation method of a Jinma Gantai preparation for treating hepatitis, belonging to the technical field of traditional Chinese medicines. The product is prepared from dichondra repens, berchemia lineate and the like and is prepared into pharmaceutically allowable dosage forms. The preparation has good stability and high bioavailability, is convenient to take, has beautiful and clean appearance and is easy to accept by the patients. The provided preparation method can be used for effectively preparing the needed preparation and ensuring that the production process of the prepared preparation is scientific and reasonable.

Description

technical field [0001] The invention relates to a preparation method of Jinmagantai preparation for treating hepatitis, and belongs to the technical field of traditional Chinese medicine. technical background [0002] According to the severity of the disease, hepatitis can be divided into common hepatitis and severe hepatitis; according to the length of the disease, it can be divided into acute hepatitis and chronic hepatitis. This disease belongs to the category of syndromes such as "jaundice", "rib pain", "fever yellow" and "urgent yellow" in traditional Chinese medicine. From the perspective of etiology of traditional Chinese medicine, damp heat is the basic cause of disease of this disease, and runs through the course of the disease from beginning to end. Jinmagantai granules are made of horseshoe gold, iron-coated gold, verbena, Fangji, Patrinia, epimedium, astragalus, red peony root, and salvia miltiorrhiza; it can clear away heat and detoxify, invigorate the spleen a...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61K9/16A61K9/20A61K9/48A61P1/16
Inventor 邬建明
Owner 明远药业有限公司
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