A method and infusion pump device for reducing flow fluctuation in liquid chromatograph

A technology of flow fluctuations and infusion pumps, which is applied in the field of liquid chromatography, can solve problems affecting analysis accuracy and mobile phase residue, and achieve the effects of reducing fluctuations, constant flow, and accurate and reliable analysis results

Active Publication Date: 2016-03-16
ANHUI WAYEE SCI & TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When analyzing a variety of substances, the mobile phase needs to be replaced, and the damper is easy to cause the residue of the mobile phase, which affects the accuracy of the analysis

Method used

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  • A method and infusion pump device for reducing flow fluctuation in liquid chromatograph
  • A method and infusion pump device for reducing flow fluctuation in liquid chromatograph
  • A method and infusion pump device for reducing flow fluctuation in liquid chromatograph

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Embodiment Construction

[0028] Such as figure 1 , 5 As shown, an infusion pump device for reducing flow fluctuations in a liquid chromatograph includes a main control device 1, the main control device 1 controls and connects a motor 10, and the motor 10 drives and connects with a cam group, and the cam group includes large cams connected in series 8. Small cam 9, large cam 8, and small cam 9 are respectively equipped with cam positioning devices, and large cam 8 and small cam 9 respectively drive plunger rod one 6 and plunger rod two 7 in cylinder one 4 and cylinder two. Alternate reciprocating motion in 5, the inlet and outlet of liquid cylinder one 4 are respectively provided with a check valve 2, the outlet of liquid cylinder one 4 is connected with liquid cylinder two 5 and is equipped with pressure detection for real-time monitoring of the pressure of the mobile phase in the system The device 3, the cam positioning device, and the pressure detection device 3 are connected with the main control ...

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Abstract

The invention discloses a method for reducing flow fluctuation in a liquid chromatograph and an infusion pump device, including a main control device, the main control device controls and connects a motor, the motor drives and connects a cam group, and the cam group includes large cams connected in series, The small cam, the large cam and the small cam are respectively equipped with cam positioning devices. The large cam and the small cam respectively drive the plunger rod 1 and the plunger rod 2 to perform alternate reciprocating motions in the liquid cylinder 1 and the liquid cylinder 2. The inlet and the outlet are respectively provided with a one-way valve, the outlet of the liquid cylinder 1 is connected with the liquid cylinder 2 and equipped with a pressure detection device for real-time monitoring of the pressure of the mobile phase in the system, and the cam positioning device and the pressure detection device are connected with the main control device. The pressure detection device is also connected with one input and output end of the comparator, and the other input end and output end of the comparator are both connected with the main control device. The invention ensures accurate and reliable analytical results of the chromatographic instrument.

Description

Technical field: [0001] The invention relates to the field of liquid chromatographs, in particular to a method for reducing flow fluctuations in liquid chromatographs and an infusion pump device. Background technique: [0002] Liquid chromatograph is a widely used analytical instrument, which uses the difference in physical and chemical properties of each component in the mixture to be separated to separate it in mobile phase and stationary phase to different degrees, and then conducts the separation of the separated components. In quantitative analysis, whether the flow rate of the mobile phase (solvent) is constant or not directly affects the detection results of the liquid chromatograph, so it is necessary to ensure that the infusion pump system provides a constant flow rate. [0003] When the infusion pump transports the solvent from the solvent bottle to the chromatographic column, the pressure of the solvent rises from one atmosphere to tens of MPa. The increase in pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): F04B1/02F04B17/03F04B49/06
Inventor 翟畅张鑫高美丽周宇
Owner ANHUI WAYEE SCI & TECH CO LTD
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