Injection for clearing heat, reducing phlegm and detoxifying

A technology of injection and form, which is applied in the direction of antipyretics, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve the problems of difficult curative effect and shortage of varieties

Inactive Publication Date: 2014-03-05
李兴惠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional Chinese medicine has a long history of treating febrile diseases. For a long time, there are mainly the Shanghan School and the Febrile Disease School. They have accumulated rich experience and have a common theoretical basis. For the characteristics of acute febrile diseases, which are characterized by rapid onset and rapid change, They established a dialectical treatment method that combines typhoid fever and febrile disease to control the disease as soon as possible, and then achieve the purpose of treatment. Although there are many kinds of Chinese patent medicines for treating this disease, there is still a shortage of varieties that are effective and quick-acting. Some Shuanghuanglian injections contain honeysuckle, Huangling and forsythia, which are suitable for the wind-warm lung-heat syndrome stage. Although it has a certain curative effect on acute febrile disease, it is not suitable for severe acute febrile disease, that is, for the exterior-interior syndrome stage and interior syndrome stage. period, because the disease is severe and the medicine is light, so the curative effect is difficult to achieve

Method used

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  • Injection for clearing heat, reducing phlegm and detoxifying
  • Injection for clearing heat, reducing phlegm and detoxifying
  • Injection for clearing heat, reducing phlegm and detoxifying

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1a

[0107] Preparation Example 1a: Preparation of Ursocholic Acid

[0108] Obtain ursodeoxycholic acid according to the method of the [0097]-[0098] section of the CN101890048A specification sheet that is embodiment 3, after measuring, wherein contain 83.3% ursodeoxycholic acid and 11.4% chenodeoxycholic acid (bear / cheese =7.3; in the following examples, in the prepared total ursodeoxycholic acid, the content of ursodeoxycholic acid: the ratio of chenodeoxycholic acid content is in the range of 5-16).

preparation example 1b

[0109] Preparation Example 1b: Preparation of Ursocholic Acid

[0110] Prepare ursocholic acid according to the example method of the [0024] paragraph of the CN1947746B description; then re-purify again: after dissolving with ethyl acetate, add an appropriate amount of water therein to obtain a precipitate, and dry in vacuum to obtain ursocholic acid, which contains 84.3% ursodeoxycholic acid.

preparation example 1c

[0111] Preparation Example 1c: Preparation of Ursocholic Acid

[0112] Prepare ursocholic acid according to the method recorded in line 21-31 on page 2 of the CN1110150A instruction manual, and then repurify again: dissolve it with ethyl acetate, add an appropriate amount of water to it to obtain a precipitate, and dry it in a vacuum to obtain ursocholic acid, which contains 80.8% ursodeoxycholic acid.

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Abstract

The invention relates to an injection for clearing heat, reducing phlegm and detoxifying. The injection comprises active substances, propylene glycol and water for injection. The active substances are prepared from the following materials: bear gall powder or ursodesoxycholic acid, cornu gorais, scutellaria baicalensis, honeysuckle and fructus forsythiae. The invention also relates to a preparation method of the injection and a pharmaceutical use thereof. The injection provided by the invention can be used for clearing heat, reducing phlegm and detoxifying; the injection can be applied to wind-warm lung-heat disease which belongs to phlegm-heat obstructing lung syndrome, and can be used for treating fever, cough, expectoration and un-comfort, swollen sore throat, thirst, reddened tongue and yellow tongue coating; the injection can be used for patients suffering early-stage pneumonia, acute bronchitis, acute attack of chronic bronchitis and upper respiratory infection with the previous syndromes.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine injection which can be used for clearing heat, resolving phlegm and detoxifying. Background technique [0002] Traditional Chinese medicine has a long history of treating febrile diseases. For a long time, there are mainly the Shanghan School and the Febrile Disease School. They have accumulated rich experience and have a common theoretical basis. For the characteristics of acute febrile diseases, which are characterized by rapid onset and rapid change, They established a dialectical treatment method that combines typhoid fever and febrile disease to control the disease as soon as possible, and then achieve the purpose of treatment. Although there are many kinds of Chinese patent medicines for treating this disease, there is still a shortage of varieties that are effective and quick-acting. Some Shuanghuanglian injections contain ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61K9/08A61P11/00A61P11/10A61P29/00A61P11/14A61P11/04A61K35/413A61K35/32A61K31/575
CPCA61K9/0019A61K9/08A61K31/575A61K35/32A61K35/413A61K36/355A61K36/539A61K36/634A61K47/10A61K2300/00
Inventor 李兴惠
Owner 李兴惠
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