Traditional Chinese medicine preparation for preventing and treating osteoporosis and preparation method of traditional Chinese medicine preparation

A traditional Chinese medicine preparation and osteoporosis technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, bone diseases, etc., can solve the problems of high price, serious toxic and side effects, etc., to improve bone density, promote osteoblast bone Forming and promoting the effect of inhibiting bone resorption of osteoclasts

Inactive Publication Date: 2014-03-26
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the clinical osteoporosis drugs have the disadvantages of relatively large toxic and side effects and high prices.

Method used

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  • Traditional Chinese medicine preparation for preventing and treating osteoporosis and preparation method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for preventing and treating osteoporosis and preparation method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for preventing and treating osteoporosis and preparation method of traditional Chinese medicine preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1 (Preparation of Longxian Recipe)

[0025] Weigh 0.5 kg of Hailong coarse powder (passed through a 60-mesh sieve) and stir evenly to form Hailong dry powder. Then weigh 0.5 kg each of Epimedium leaf and Cuscuta, add 10 times the weight volume of the water to decoct 3 times, 2 hours each time, filter, combine the filtrate, add Hailong dry powder, mix well, dry under reduced pressure to solid, crush , Go through a 60-mesh sieve, and get the dragon fairy formula

Embodiment 2

[0026] Example 2 (Preparation of Longxian Recipe)

[0027] Weigh 0.5 kg of Hailong coarse powder (passed through a 60-mesh sieve) and stir evenly to form Hailong dry powder. Then soak in 10 times the amount of 70% ethanol, and extract at 70℃ reflux for 3 times, 2 hours each time, to obtain the extract; filter the obtained extract, combine the filtrate, recover ethanol under reduced pressure, and continue to concentrate to 60℃ relative density 0.8-1.2kg / L, get sea dragon extract concentrate. Weigh 0.5 kg each of Epimedium leaf and Cuscuta, add 20 times the weight volume to each of them, and decoct them twice, 1 hour each time, filter, combine the filtrate, add Hailong dry powder or Hailong extract concentrate, mix well, and reduce pressure Dried into a solid, crushed, and passed through a 60-mesh sieve to obtain the Longxian formula.

Embodiment 3

[0028] Example 3 (Preparation of Longxian Recipe)

[0029] Weigh 0.5 kg of Hailong coarse powder (passed through an 80-mesh sieve) and stir evenly to form Hailong dry powder. Then soak with 20 times the amount of 50% ethanol, and extract 3 times at 80°C under reflux for 1 hour each time to obtain the extract; the obtained extracts are filtered, the filtrate is combined, the ethanol is recovered under reduced pressure, and the concentration is continued to 60°C relative density 0.8-1.2kg / L, get sea dragon extract concentrate. Weigh 0.5 kg each of Epimedium Leaf and Cuscuta, add 10 times the weight volume, respectively, and decoct 3 times in water for 1 hour, filter, combine the filtrate, add Hailong dry powder or Hailong extract concentrate, mix well, and reduce pressure Dried into a solid, crushed, and passed through an 80-mesh sieve to obtain the Longxian prescription.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for preventing and treating osteoporosis. The traditional Chinese medicine preparation is prepared from the following crude drugs in parts by weight: 1-10 parts of sea otter, 10-50 parts of epimedium herbs and 10-50 parts of semen cuscutae. Proved by pharmacodynamic study, the traditional Chinese medicine preparation disclosed by the invention can be used for remarkably improving the physiological status of a rat bone with osteoporosis caused by estrogen deficiency, enhancing the strength and toughness of the bone, obviously promoting the bone forming ability of an osteoblast and remarkably inhibiting the bone absorbing ability of an osteoclast so as to have a remarkable effect for preventing and treating postmenopausal osteoporosis. The invention also discloses a preparation method of a traditional Chinese medicine preparation for treating the postmenopausal osteoporosis.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation for preventing and treating osteoporosis; in addition, the invention also relates to a preparation method of the traditional Chinese medicine preparation. Background technique [0002] Osteoporosis is one of the common diseases in postmenopausal women and the elderly. In recent years, the prevalence and mortality of osteoporosis have continued to rise, bringing a huge burden to the entire society. However, most of the clinical treatment of osteoporosis drugs have the disadvantages of large side effects and high prices. Traditional Chinese medicine believes that "kidney deficiency" is the basic pathological factor for osteoporosis. Therefore, scientists continue to devote themselves to the development of new drugs from the abundant resources of kidney-tonifying Chinese medicine. Summary of the invention [0003] The technical problem to be solved by the present invention is to provide a tr...

Claims

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Application Information

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IPC IPC(8): A61K36/39A61P19/10A61K35/56A61K35/60
Inventor 秦路平蒋益萍薛黎明黄宝康
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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