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A kind of traditional Chinese medicine composition and its application in the preparation of traditional Chinese medicine preparation for treating osteoporosis

A traditional Chinese medicine preparation, osteoporosis technology, applied in the direction of drug combination, medical formula, bone diseases, etc., can solve the problem of Da Bushen Decoction, such as cold, cool, greasy medicinal taste, insufficient power of warming yang and transforming qi, easy damage to spleen and stomach yang qi, etc. To achieve the effect of improving bone biomechanics, improving osteoporosis, and inhibiting bone resorption

Active Publication Date: 2022-03-25
李鼎鹏 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Da Bushen Decoction provides a good reference for traditional Chinese medicine to treat osteoporosis through tonifying kidney essence, but Da Bushen Decoction has a wide range of indications, and there are still some limitations and deficiencies in the treatment of osteoporosis, mainly: osteoporosis and kidney deficiency The pathogenesis is the main line, and the kidney is used as the main method to send prescriptions and medicines. In clinical practice, the pathogenesis of osteoporosis has different syndromes, such as deficiency of kidney yang, deficiency of kidney yin, and deficiency of both yin and yang. Bushen Decoction is mainly composed of traditional Chinese medicines for nourishing yin and nourishing kidney. It has a strong effect of nourishing yin and reducing fire, but the power of warming yang and transforming qi is insufficient. At the same time, Dabushen Decoction has too much taste of cold and greasy medicine. Long-term use of the medicine will easily nourish and hinder the stomach. Excessive cold and cool can easily damage the yang qi of the spleen and stomach, which will intensify the imbalance of yin and yang in the kidneys. Therefore, Dabushen decoction is mainly used to nourish the kidney and replenish essence, and at the same time, dialectical addition and subtraction should be combined with the differences in yin and yang of the five internal organs.

Method used

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  • A kind of traditional Chinese medicine composition and its application in the preparation of traditional Chinese medicine preparation for treating osteoporosis
  • A kind of traditional Chinese medicine composition and its application in the preparation of traditional Chinese medicine preparation for treating osteoporosis
  • A kind of traditional Chinese medicine composition and its application in the preparation of traditional Chinese medicine preparation for treating osteoporosis

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Experimental program
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Effect test

Embodiment 1

[0016] Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: 25g of rehmannia glutinosa, 20g of bamboo leaves, 15g of licorice, 15g of Eucommia ulmoides, 10g of drynariae, Knee 10g, Psoralen 10g, Guizhi 10g, Dried Ginger 10g, Epimedium 10g, Cistanche 10g, Schisandra 10g, Alisma 10g.

[0017] Clinical validation:

[0018] 1. Case selection: 120 outpatients with osteoporosis in Gansu Hospital of Traditional Chinese Medicine were selected, including 63 males and 57 females; aged 55-85 years. They were randomly divided into control group and experimental group, 60 cases in each group. There was no significant difference between the two groups in age, height, weight and other baseline data ( P >0.05), it is comparable.

[0019] The diagnostic criteria refer to the standards of the World ...

Embodiment 2

[0035]Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: rehmannia glutinosa 35g, bamboo leaves 30g, licorice 25g, Eucommia ulmoides 25g, drynaria rhizome 20g, bovine Knee 20g, Psoralen 20g, Guizhi 20g, Dried Ginger 20g, Epimedium 20g, Cistanche 20g, Schisandra 20g, Alisma 20g.

Embodiment 3

[0037] Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: Rehmannia glutinosa 30g, bamboo leaves 25g, licorice 20g, Eucommia ulmoides 20g, Drynaria rhizome 15g, bovine Knee 15g, Psoralen 15g, Guizhi 15g, Dried Ginger 15g, Epimedium 15g, Cistanche 15g, Schisandra 15g, Alisma 15g.

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Abstract

The invention discloses a traditional Chinese medicine composition, which is prepared from the following raw materials: rehmannia glutinosa, bamboo leaves, licorice, Eucommia, rhizoma drynariae, achyranthes bidentata, psoraleae, cassia twig, dried ginger, epimedium, cistanche, Schisandra, Alisma; and its application in the preparation of traditional Chinese medicine preparations for the treatment of osteoporosis is provided. The beneficial effect of the present invention is: the traditional Chinese medicine composition of the present invention and the traditional Chinese medicine preparation for treating osteoporosis can aim at the pathological mechanism of osteoporosis, deficiency of kidney essence, deficiency of kidney qi, deficiency of kidney yang, deficiency of kidney yin For treatment, it is suitable for osteoporosis of various TCM syndrome types. The main indications are pain in the waist and knees, weakness of the muscles and bones, flaccidity of the muscles and bones, pain in the waist and knees, inability to walk, dizziness, hotness due to deficiency, dysuria, pulse Weak numbers; through modern medical research, it has been found that this formula can improve osteoporosis, increase bone mineral content, improve bone biomechanics, promote bone formation, inhibit bone resorption, and reduce the high turnover state of bone.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and its application in preparing traditional Chinese medicine preparations for treating osteoporosis. Background technique [0002] Osteoporosis belongs to the category of "bone impotence" and "bone dryness" in traditional Chinese medicine. Traditional Chinese medicine believes that this disease is mostly caused by insufficient congenital endowment, lack of recuperation the day after tomorrow, long-term illness without treatment, and aging. The pathogenesis is mainly kidney deficiency, spleen deficiency, blood stasis and so on. As early as in the Huangdi Neijing "Suwen impotence theory", it is recorded: "If the kidney qi is hot, the waist and spine will not move, the bones will dry up and the marrow will decrease, and the hair will become bone impotence." That is, bone flaccidity is caused by kidney de...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P19/10
CPCA61K36/804A61K36/899A61K36/484A61K36/46A61K36/126A61K36/21A61K36/487A61K36/54A61K36/9068A61K36/296A61K36/64A61K36/79A61K36/57A61K36/884A61P19/10A61K2300/00
Inventor 李鼎鹏谢兴文郑先丽
Owner 李鼎鹏
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