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33 results about "Bone biomechanics" patented technology
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Health product for increasing bone density and preparation method of health product
InactiveCN104431684AImprove adsorption capacityStrong adsorption effect is stronger; 3) water holding capacityFood preparationRe absorptionIncreased Bone Density
The invention discloses a health product for increasing bone density and a preparation method of the health product. Chinese dwarf cherries, Chinese herbal medicine extracts refined by adopting a modern extraction technology and other raw materials having the function of increasing the bone density are scientifically compounded and are scientifically combined omnibearingly to play a synergistic effect, so as to effectively promote the calcium absorption in multiple aspects, repair and reconstruct the cartilago articularis, promote the generation of synovial fluid, promote the synthesis of collagen in cartilago articularis substrates, prevent the further degradation of cartilage, indirectly reduce the osteoclast function, inhibit the re-absorption of bones, increase the content of bone calcium and perfect the biomechanical properties of the bones, so that the product has a good function of increasing the bone density. A microwave drying technology in the preparation method can be used for further improving the integration and biological stability of the health product, and by means of the antioxidant activity of a grape seed extract in the raw materials, the strong adsorption and inclusion functions of modified dietary fibers and the antifungal propertie of the Chinese herbal medicine extracts, an efficient, safe, nutritional and stable health product having the function of increasing the bone density is prepared finally.
Owner:邵素英
Bone biomechanical measurement device
InactiveCN101886995AEasy to measureImprove adaptabilityMaterial strength using tensile/compressive forcesMaterial strength using steady bending forcesMeasurement deviceData acquisition
The invention discloses a bone biomechanical measurement device. The device is used for measuring single parameters of bones such as three mechanical parameters of bone pull pressure, torsion and bending; the fatigue parameter measurement comprises measurement of bone pull pressure, torsion and bending fatigue parameters; and the composite mechanical property measurement is the mechanical property measurement when the bone is subjected to composite stress. The bone biomechanical measurement device comprises a host system and a control system; the host system comprises a host mechanical system, a servo motor controller for driving a servo motor, a pull pressure sensor for measuring pull pressure of the bone, a bending pressure sensor for measuring the bending force of the bone, and a displacement sensor for measuring the pull pressure of the bone to generate pull pressure deformation; and the control system comprises a programmable controller, a data acquisition controller and a measurement control processor. The bone biomechanical measurement device not only realizes the measurement of single mechanical properties when the bone is acted with pull pressure, torsion and bending respectively, but also realizes the fatigue mechanical property measurement of the bone and the composite mechanical property measurement when the bone is acted with pull pressure, torsion and bending at the same time.
Owner:BEIHANG UNIV
Composition for increasing bone mineral density and preparation method of composition
InactiveCN104489699AImprove adsorption capacityStrong adsorption effect is stronger; 3) water holding capacityOrganic active ingredientsPeptide/protein ingredientsRe absorptionMechanical property
The invention discloses a composition for increasing bone mineral density and a preparation method of the composition. Chinese dwarf cherry, a Chinese herbal medicine extract refined by a modern extraction technology and other raw materials with the function of increasing the bone mineral density are scientifically compounded, are scientifically combined in an omnibearing manner, and work together, so as to achieve the effects of effectively promoting absorption of calcium from a plurality of aspects, restoring and rebuilding cartilago articularis, creating synovial fluid, and promoting collagen synthesis in the cartilago articularis, preventing cartilage from further degenerating, indirectly reducing osteoclast action, inhibiting re-absorption of bones, increasing bone calcium content and improving the mechanical property of the bone, so that the product has a good effect of increasing the bone mineral density. The integrating property and the biological stability of the composition can be further improved by a microwave drying technology in the preparation method. Due to the oxidation resistance of a grape pip extract in the raw materials, high adsorption and embedding effects of modified dietary fiber, and antifungal properties of the Chinese herbal medicine extract, the efficient, safe, nutrient and stable composition with the function of increasing the bone mineral density is finally prepared.
Owner:邵素英
Prosthetic socket having deformation adjusting and controlling function and 4D printing forming method of prosthetic socket
ActiveCN109717991AImprove wearing comfortImprove the safety of useAdditive manufacturing apparatusProsthesisCarrying capacityHardness
The invention provides a prosthetic socket having a deformation adjusting and controlling function. The prosthetic socket comprises an inner cavity and an outer cavity, wherein the inner cavity is made from intelligent deformable materials; the outer cavity is made from polymer structure materials having better carrying capacity; and the thickness ratio of the inner cavity to the outer cavity is 1to (3-5). The inner cavity made from the intelligent deformable materials is introduced into a prosthetic socket through a 4D printing technique to form the prosthetic socket having a deformation adjusting and controlling function, a hard and soft coupled prosthetic socket having human body biological mechanical properties is printed layer by layer according to parameters of three-dimensional pattern data, biological mechanics characteristics of muscle and bone and the like of disabled limbs of a wearer, under the excitation of an outer field, the inner cavity produces intelligent chronologydeformation of expanding, distorting, folding and the like, the shape and the hardness of the inner part of the prosthetic socket are dynamically adjusted, the jointing degree of the prosthetic socketand the disabled limbs of the wearer is improved, the uniformity of pressure distribution between the prosthetic socket and the interface of the disabled limbs of the wearer is strengthened, and thedressing comfortability and the use safety of the wearer are improved.
Owner:国家康复辅具研究中心
Traditional Chinese medicine compound preparation for treating osteoporotic fractures and preparation method and application thereof
The invention discloses a traditional Chinese medicine compound preparation for treating osteoporotic fractures. The compound preparation is prepared from traditional Chinese medicine for strengthening the spleen and reinforcing the kidney and pharmaceutical excipients, wherein the traditional Chinese medicine for strengthening the spleen and reinforcing the kidney is prepared, by weight, 6-30 parts of codonopsis pilosula, 6-30 parts of acanthopanax senticosus, 6-30 parts of drynaria rhizome, 6-30 parts of epimedium, 6-15 parts of salvia miltiorrhiza and 3-12 parts of angelica pubescens. According to the traditional Chinese medicine compound preparation for the treating osteoporotic fractures, a formula for strengthening the spleen and reinforcing the kidney is based on a spleen-kidney-related theory that the kidney is a congenital origin and the spleen is an acquired foundation, through animal experiments, it is found that the formula for strengthening the spleen and reinforcing the kidney can significantly promote healing of bone calluses in different periods of ovariectomized mice suffering from the osteoporotic fractures, the bone mass and biomechanical strength of the bone calluses are improved, the expression of beta-catenin in fractured bone end muscles and bone calluses is promoted, the number of muscle-derived stem cells in the fractured bone end muscles is increased, the proliferative activity is promoted, the muscle-derived stem cells are promoted to migrate to the bone calluses, and therefore osteogenic differentiation is simulated, and healing of the osteoporotic fractures is accelerated. The invention further discloses a preparation method and medicinal application of the traditional Chinese medicine compound preparation.
Owner:LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
Pharmaceutical compositions for improving bone loss of hyperthyroid high-conversion type and reduction of biomechanical properties of bone
InactiveCN108578470AAdjust densityWell mixedSkeletal disorderAldehyde active ingredientsSalvia miltiorrhizaBone density
The invention provides pharmaceutical compositions for improving the bone loss of hyperthyroid high-conversion type and the reduction of the biomechanical properties of the bone, and relates to an extract of a Chinese medicinal Danshen, or the formula and the production process of pharmaceutical compositions for improving the bone loss of high-conversion type and the reduction of the biomechanicalproperties of the bone caused by the hypersplenism of the thyroid, which is prepared from the following components in parts by weight: 0.1 to 0.3 g of a danshensu and 5 g of crystalline fructose, thepharmaceutical compositions are characterized by being prepared into an injection. The invention further discloses a formula and production process of the injection, a granule and a non-alcoholic beverage. The high-dose thyroxine-induced hyperthyroid high-conversion bone loss animal model proves that the pharmaceutical composition prepared from the danshensu and the fructose can influence the bone metabolism of the rat, promote the bone formation, inhibit the bone resorption, increase the bone mass, improve the bone mineral density and the bone mineral salt content, and improve the performance of the bone biomechanics, and has a good preventive effect on the damage of the bone biological biomechanical properties of the hyperthyroid osteoporosis.
Owner:GUANGDONG SPRINGYOUNG BIOTECH +1
Fructose and dried tangerine peel-containing health food for strengthening bones and muscles and improving exercise performance and its formula and production process
Disclosed are a fructose and dried tangerine peel-containing health food for strengthening bones and muscles and improving exercise performance and its formula and production process, aiming to overcome muscle injury and pain, dysfunction and bone fracture which are easy to be caused by excessive movement. The health food comprises five different preparations, and is characterized in that the health food refers to a compound comprising 12% of fructose and 50% of dried tangerine peel and having prevention function on reduction of bone biomechanical property and muscle fatigue caused by excessive movement, sport injury, diseases or senility. According to the formula, fructose can replenish necessary life energy to muscles, enter the muscles directly rather than by the way of insulin, and canbe converted into muscle glycogen directly to overcome metabolic disturbance caused by energy deficiency to muscle tissue cells; dried tangerine peel can improve bone biomechanical property, especially improve synthesis of bone collagen, improve elastic load of bones greatly so as to prevent bones from being easy fracture during exercise, and is effective in strengthening bones and muscles and improving exercise performance together with fructose.
Owner:GUANGDONG SPRINGYOUNG BIOTECH +1
Application of rare earth 1-hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt
InactiveCN105079008ADecreased bone biomechanical strengthGood treatment effectOrganic active ingredientsSkeletal disorderSide effectOsteoblast
The invention discloses application of a rare earth 1-hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt. The rare earth 1-hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt is applicable to preparation of an anti-osteoporosis drug. The anti-osteoporosis drug has an obvious function of treating the symptoms that the osteoblast activity and the bone biomechanical strength of an osteoporosis model rat are reduced, is free from obvious toxic and side effects, and has a broad application prospect.
Owner:HAINAN NORMAL UNIV
Automated patient-specific method for biomechanical analysis of bone
ActiveUS9937011B2Reduce in quantityFlat surfaceDetails involving 3D image dataCharacter and pattern recognitionMedicineHand held
A computer-implemented method for providing FEA analysis of at least a portion of at least one bone in a patient, the method comprising steps of: providing at least one image of at least a portion of a bone; selecting at least a portion of the bone; automatically performing an FE analysis of the selected portion of the bone; and displaying at least one result of the FE analysis. Bone selection and display of the bone, the selected portion thereof, and the results of the FE analysis occur via a hand-held device, with processing and data storage performed remotely.
Owner:PERSIMIO LTD
Bone biomechanical modeling method, system and device based on multi-modal image
The embodiment of the invention discloses a bone biomechanical modeling method, system and device based on a multi-modal image, and the method comprises the steps: carrying out the calculation of a fat fraction image through employing a water image and a fat image extracted from an MRI image, carrying out the image registration of the fat fraction image and a QCT image to obtain an image bone marrow fat fraction, correcting a CT value of the QCT image by using the image bone marrow fat fraction, establishing a bone biomechanical finite element model by using the corrected CT value, and performing bone biomechanical calculation and analysis. Therefore, the correction of the material attribute of the bone biomechanical model is taken as an entry point, the problem that the material attribute of the existing bone biomechanical model is inaccurate is solved, the bone biomechanical finite element model is established based on multi-modal image correction, and the method has important significance in improving the bone biomechanical model and improving the accuracy of clinical fracture risk prediction.
Owner:BEIJING UNIV OF TECH
Traditional Chinese medicine composition for treating rheumatoid arthritis and bone destruction and application of traditional Chinese medicine composition
InactiveCN105687397ASignificant inhibitory effect on toe swellingInhibition of toe swellingDispersion deliveryAntipyreticSide effectRhizome
The invention relates to traditional Chinese medicine composition for treating rheumatoid arthritis and bone destruction and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from raw materials in parts by weight as follows: 10-20 parts of Japan sabia, 15-30 parts of malaytea scurfpea fruits, 15-30 parts of fortune's drynaria rhizomes, 9-15 parts of Chinese angelica and 15-20 parts of epimedium herbs. The traditional Chinese medicine composition has a remarkable inhibition function on toe swelling of a rheumatoid arthritis animal model, can remarkably reduce loss of bone mass around an inflammable joint of the rheumatoid arthritis animal model, improves the bone biomechanical parameter and inhibits bone destruction caused by rheumatoid arthritis; the traditional Chinese medicine composition has the advantages that a few raw materials are required, preparation is convenient, the cost is low, and no toxic and side effects are caused.
Owner:肖涟波 +2
Traditional Chinese medicine composition and application thereof in preparation of traditional Chinese medicine preparation for treating osteoporosis
ActiveCN111760011AIncrease mineral contentImproved biomechanicsSkeletal disorderPlant ingredientsYin deficiencyDrynaria
A traditional Chinese medicine composition is prepared from the following raw material: rehmannia, bamboo leaves, liquorice, eucommia ulmoides, rhizoma drynariae, radix achyranthis bidentatae, fructuspsoraleae, cassia twig, dried ginger, herba epimedii, herba cistanche, schisandra chinensis and rhizoma alismatis. The invention further provides application of the traditional Chinese medicine composition in preparation of a traditional Chinese medicine preparation for treating osteoporosis. The traditional Chinese medicine composition and the traditional Chinese medicine preparation for treatment osteoporosis have the beneficial effects that pathology can be carried out on treatment mechanisms of osteoporosis, kidney essence deficiency, kidney qi deficiency, kidney yang deficiency and kidney yin deficiency, and the traditional Chinese medicine composition and the traditional Chinese medicine preparation are suitable for osteoporosis of various traditional Chinese medicine syndrome types; the traditional Chinese medicine composition is mainly suitable for treating symptoms such as waist and knee aching pain, muscle and bone weakness, muscle and bone weakness, waist and knee pain, walking failure, dizziness, deficiency-heat rushing adverse flow, difficult urination and weak pulse; modern medical research finds that the formula has the effects of improving osteoporosis, increasingthe bone mineral content, improving bone biomechanics, promoting bone formation, inhibiting bone resorption and reducing the high conversion state of bones.
Owner:李鼎鹏 +2
Naringin preparations for improving male osteoporosis to prevent bone fracture
InactiveCN110934883ASalicyclic acid active ingredientsHydroxy compound active ingredientsNaringinFructose
Along with the increase of age, the testosterone levels of middle-aged and elderly men are gradually reduced and the bone biomechanical properties are reduced, so that bone fracture and osteoporosis easily occur. The research discovers that a preparation composed of naringin and fructose can replace testosterone to prevent male osteoporosis and reduced bone biomechanical properties. The naringin is natural flavanone glycosides and the fructose is a special energy supplement; and the naringin and fructose are combined according to the ratio of 1: (3-4) to prepare oral liquid, a capsule, a tablet, a granule, oral liquid and beverage, thereby preventing and treating people suffering from the bone biomechanical property reduction and osteoporosis due to various factors. In addition, the invention also discloses formulas and production processes of naringin-fructose oral liquid, a naringin-fructose vitamin D calcium granule, a naringin-fructose estrogen tablet, and a naringin-fructose aspirin tablet. The products have good effects on preventing male osteoporosis and low bone biomechanical function as well as the good curative effect on female osteoporosis patients.
Owner:湛江广医资产经营有限公司 +1
Natural drug composition for treatment of osteoporotic fracture and/or osteoarthritis and application thereof
ActiveCN106333977AIncrease bone densityImprove bone morphologySkeletal disorderPlant ingredientsDiseaseTibia
Belonging to the technical field of research on the dose-effect of natural drug prescription compatibility and use, the invention discloses a natural drug composition for treatment of osteoporotic fracture and / or osteoarthritis and application thereof. The natural drug composition comprises, by mass percentage, 73.3%-98.3% of sea buckthorn fruit oil and 1.7%-26.7% of panax notoginseng saponins. The natural drug composition can transform and generate a signal molecule of eicosatrienoic acid, and the signal molecule can activate protein and cyclic nucleotide, calcium ion and other multi-path molecular signal pathways to generate the effect of synergistic amplification of signal molecule; the composition can improve the hematopoietic microenvironment, regulate endocrine, adjust the metabolic balance of osteoclast and osteoblast, reduce alkaline phosphatase, improve serum osteoprotegerin, osteocalcin and other bone metabolism marker indexes, increase the femur, tibia and vertebral bone density, significantly improves the bone remodeled bone shape and bone biomechanical symbolic indexes, and can effectively prevent and treat osteoporotic fracture, osteoarthritis and ostealgia diseases.
Owner:ZHEJIANG INNOVATION WISDOM VALLEY TECH CO LTD
Drug with anti-osteoporosis effect
InactiveCN103284990AEnhanced bone biomechanical strengthIncreased bone biomechanical strengthOrganic active ingredientsSkeletal disorderSide effectTreatment effect
Owner:苏州同立医药技术有限公司
Preparation method of phosphorylated krill peptide for preventing and treating osteoporosis
ActiveCN103937862AHigh in proteinNo pollution in the processHydrolysed protein ingredientsSkeletal disorderPhosphorylationPhosphate
The invention provides a phosphorylated krill peptide. A preparation method comprises the following steps: (1) degreasing krill powder, then adding a NaOH solution into the krill powder and centrifuging to obtain a supernatant, regulating a pH value of the supernatant until reaching the isoelectric points of protein and centrifuging to obtain a precipitate; (2) preparing the krill protein precipitate into an aqueous solution, adding a phosphate, regulating the pH value of the solution and performing spray drying on the solution so as to obtain krill protein powder; standing the krill protein powder at a high temperature so as to obtain phosphorylated krill protein; (3) repeatedly washing the phosphorylated krill protein with distilled water and centrifuging; and (4) preparing the phosphorylated krill protein into the aqueous solution, adding 2M NaOH, regulating the pH value of the solution, adding a protease into the solution, hydrolyzing for 3 to 6 hours at a proper temperature, heating to 100 DEG C and stopping an enzyme reaction, centrifuging to obtain the supernatant and performing the spray drying on the supernatant so as to obtain the phosphorylated krill peptide. The animal experiment proves that the prepared phosphorylated krill peptide can be used for obviously regulating the bone metabolism level of a model rat with the osteoporosis so as to enhance the bone mineral density and improve the bone biomechanical property, thereby having obvious functions for preventing and treating the osteoporosis.
Owner:OCEAN UNIV OF CHINA
Application of rare earth alendronate in preparation of osteoporosis treatment drug
InactiveCN105796595ADecreased proliferative activityDecreased bone densityHeavy metal active ingredientsOrganic active ingredientsSide effectCerium
The invention discloses an application of rare earth alendronate in preparation of an osteoporosis treatment drug. The rare earth alendronate comprises one or more of alendronate lanthanum, alendronate cerium, alendronate praseodymium, alendronate neodymium, alendronate promethium, alendronate samarium, alendronate europium and alendronate gadolinium. The osteoporosis treatment drug prepared from rare earth alendronate has obvious therapeutic action on reduction of osteoblast viability and reduction of bone biochemical strength of a model rat with osteoporosis and does not have obvious toxic and side effects.
Owner:HAINAN NORMAL UNIV
Bone biomechanical measurement device
InactiveCN101886995BObtain comprehensive mechanical propertiesEasy to measureMaterial strength using tensile/compressive forcesMaterial strength using steady bending forcesMeasurement deviceData acquisition
The invention discloses a bone biomechanical measurement device. The device is used for measuring single parameters of bones such as three mechanical parameters of bone pull pressure, torsion and bending; the fatigue parameter measurement comprises measurement of bone pull pressure, torsion and bending fatigue parameters; and the composite mechanical property measurement is the mechanical property measurement when the bone is subjected to composite stress. The bone biomechanical measurement device comprises a host system and a control system; the host system comprises a host mechanical system, a servo motor controller for driving a servo motor, a pull pressure sensor for measuring pull pressure of the bone, a bending pressure sensor for measuring the bending force of the bone, and a displacement sensor for measuring the pull pressure of the bone to generate pull pressure deformation; and the control system comprises a programmable controller, a data acquisition controller and a measurement control processor. The bone biomechanical measurement device not only realizes the measurement of single mechanical properties when the bone is acted with pull pressure, torsion and bending respectively, but also realizes the fatigue mechanical property measurement of the bone and the composite mechanical property measurement when the bone is acted with pull pressure, torsion and bending at the same time.
Owner:BEIHANG UNIV
A preparation method of phosphorylated krill peptide capable of preventing and treating osteoporosis
ActiveCN103937862BHigh in proteinNo pollution in the processHydrolysed protein ingredientsSkeletal disorderPhosphateProtein
Owner:OCEAN UNIV OF CHINA
Application of Sare Shisanwei Pengniao pills to osteoporosis treatment medicine preparation
The invention relates to application of Tibetan medicine-Sare Shisanwei Pengniao pills to osteoporosis treatment medicine preparation. The application overcomes technology biases on the aspect of application in the prior art, and the Sare Shisanwei Pengniao pills play a remarkable improvement role in model rat bone density, a bone biomechanics index, an HOP index in urine and a serum biochemical index and can be used for osteoporosis treatment, particularly treating osteoporosis resulting from estrogen lack.
Owner:SHANDONG JINHE DRUG RES DEV
Application of peony seed oil in preparation of drugs and health food for improving male bone biomechanical properties
With the increase of age, the testosterone level of middle-aged and elderly men gradually decreases, the bone biomechanical properties decrease, and fracture and osteoporosis are easy to occur. Testosterone deficiency is believed to be one of the main causes of osteoporosis in men. Our research found that peony seed oil has the same effect as testosterone, has a certain antagonistic effect on thedecrease of bone biomechanical properties and osteoporosis caused by testis-removed mice. The peony seed oil provided by the invention can be made into soft capsules, hard capsules, tablets, granules,oral liquids and beverages that can be used for clinical application, and is used for preventing and treating male osteoporosis patients and people whose bone biomechanical properties are reduced dueto various reasons. The invention also discloses formulas and preparation technologies of peony seed oil soft capsules, peony seed oil vitamin D calcium soft capsules, peony seed oil estrogen soft capsules and peony seed oil aspirin soft capsules, which have good effects of preventing and treating low bone biomechanical function and osteoporosis of various populations.
Owner:GUANGDONG MEDICAL UNIV +1
Formula and production technology of health-care food and medicine composed of fructose and radix astragali seu hedysari and used for preventing and treating muscle atrophy
The invention provides a formula and production technology of one group of health-care foods and medicines composed of fructose and radix astragali seu hedysari and used for preventing and treating muscle atrophy. Osteoporosis and the muscle atrophy are common symptoms occurred along with human body aging; commonly, legs become old before people get old; the invention discloses one group of the health-care foods and medicines composed of the fructose and the radix astragali seu hedysari and used for preventing and treating the muscle atrophy, and one group of the health-care foods and medicines comprises 7 preparations with different preparation forms and is characterized in that a composition is composed of 12 percent of the fructose and 50 percent of the radix astragali seu hedysari; thecompositions have very good prevention and treatment effects on muscle fatigues, muscle loss, the muscle atrophy and bone biomechanics performance degradation caused by excessive exercise, damages, diseases or ageing; the fructose in the formula can be used for enabling muscle to obtain energy supplementation needed by lives; the fructose can directly enter the muscle, without the need of an insulin way, and is directly transformed into muscle glycogen; metabolic disorders caused by the fact that muscle tissue cells are lack of energy are supplemented in time; meanwhile, the radix astragali seu hedysari can be used for promoting the repairing of muscle tissues and the synthesis of protein, so that the muscle is stronger and more powerful; the fructose and the radix astragali seu hedysariare combined and commonly play a role of strengthening bones and the muscle and preventing and controlling the muscle atrophy.
Owner:GUANGDONG SPRINGYOUNG BIOTECH +1
Experimental device for generating standard bone injury
InactiveCN105719549APrecise control and adjustment of impact forceRepeatableEducational modelsCircular discEngineering
The invention provides an experimental device for generating standard bone injury and belongs to the field of the experimental device. A vertical column is arranged on a base; a top horizontal block is arranged at the top end of the vertical column; a guiding bracket is arranged in the middle of the vertical column; a slide rod is arranged at a cantilever end of the top horizontal block; a disc is arranged on the slide rod; a spring is arranged between the disc and the upper end of the guiding bracket; a blade is arranged at the lower end of the slide rod; a slide block set is arranged on the base under the blade; a sample platform is arranged on a side wall of the slide block set; and a counterweight sleeves the slide rod in a sliding form. The experimental device is used for generating the standard bone injury of an experimental bone sample by supplying a magnitude-specified and value-adjustable impact force, so as to accurately and quantitatively realize the dynamic breakage feature experiment of the bone sample; the repeatability of the experimental result is excellent; the batch acquisition or preparation for the standard bone injury sample or model can be conveniently realized; and the experimental device can be widely applied to the experimental field of bone biomechanical property research and bone sample dynamic breakage features.
Owner:SHANGHAI UNIV OF MEDICINE & HEALTH SCI
Pharmaceutical composition for treating osteoporosis and preparing method thereof
The invention discloses a pharmaceutical composition for treating osteoporosis and a preparing method thereof. The pharmaceutical composition is prepared from conic gymnadenia rhizome, west szechwan pyrethrum, ginseng, cortex lycii radicis, tinospora sinensis stem, yak bone, rhizoma anemarrhenae and concha margaritifera. The preparing method comprises the steps of smashing concha margaritifera into fine powder and conducting heat extraction on other medicinal materials, combining extracting solutions and conducting concentration to dry, adding the concha margaritifera fine powder, and conducting even mixing. It is found through pharmacological research that aqueous extracts and alcohol extracts, especially acidity alcohol extracts, of the pharmaceutical composition have certain curative effect on the bone mineral density and bone biomechanics index of the thighbone and tibia of an osteoporosis model rat, the indexes of calcium and BGP in serum, and the index of HOP in urine, and the pharmaceutical composition can be used for treating osteoporosis, especially osteoporosis caused by estrogen deficiency.
Owner:ZIBO VOCATIONAL INST
Traditional Chinese medicine composition for treating deficiency of spleen and stomach qi type postmenopausal osteoporosis
InactiveCN104706889AReduced responseLittle side effectsSkeletal disorderPlant ingredientsSide effectBone density
The invention relates to a traditional Chinese medicine composition for treating deficiency of spleen and stomach qi type postmenopausal osteoporosis, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from medical raw materials: radix astragali, stir-baked rhizoma dioscoreae, rhizoma atractylodis macrocephalae, radix acanthopanacis semticosi, fructus psoraleae, eucommia ulmoides, sargentodoxa cuneata and radix aucklandiae, and can be prepared into multiple dosage forms. The medicines are organically combined, and have the effects of regulating spleen and stomach, tonifying kidney and nourishing stomach, strengthening tendons and bones, promoting blood circulation to remove meridian obstruction, and relieving pain. The traditional Chinese medicine composition is small in adverse reaction and side effect, is high in treatment rate and effective rate, improves the bone density, increases the bone mineral content, improves the bone biochemistry state, and treats both manifestation and root causes of the deficiency of spleen and stomach qi type postmenopausal osteoporosis while improving the deficiency of spleen and stomach qi type postmenopausal osteoporosis.
Owner:陈红
An experimental setup for generating standard bone lesions
InactiveCN105719549BPrecise control and adjustment of impact forceRepeatableEducational modelsEngineeringRepeatability
Owner:SHANGHAI UNIV OF MEDICINE & HEALTH SCI
Medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and preparation method thereof
ActiveCN109106913ADoes not limit the scope of protectionComponent separationInanimate material medical ingredientsBone densityLumbricus
The invention belongs to the field of traditional Chinese medicines, and relates to a medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 2 to 8 parts of radix astragali seu hedysari, 2 to 8 parts of bighead atractylodes rhizome, 2 to 8 parts of Chinese angelica, 2 to 8 parts of radix puerariae, 2 to 8 parts of radix salviae miltiorrhizae, 2 to 8 parts of radix curcumae, 2 to 8 parts of radix achyranthis bidentatae, 1 to 4 parts of radix rehmanniae preparata, 1 to 4 parts of lumbricus, 1 to 4 parts of deer-horn glue, 1 to 4 parts of turtle shell, 1 to 4 parts of dragon bone, and 1 to 4 parts of concha ostreae. The medicine with effects of producing marrow and strengthening bone has the advantages that the bone density BMC is increased, and the content of bone mineral (BMD) is increased; various indexes of biological and mechanical properties of bone, such as maximum load, extreme strength, maximum flexibility, and elastic modulus, can be obviously improved, and the bone hardness and bone elasticity are improved.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE
A marrow-growing and bone-strengthening medicine for treating alcoholic osteoporosis and its preparation method
ActiveCN109106913BDoes not limit the scope of protectionComponent separationInanimate material medical ingredientsSalvia miltiorrhizaAngelica Sinensis Root
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE
Application of Sare Thirteen Wei Pengniao Pills in the Preparation of Drugs for Treating Osteoporosis
The invention relates to application of Tibetan medicine-Sare Shisanwei Pengniao pills to osteoporosis treatment medicine preparation. The application overcomes technology biases on the aspect of application in the prior art, and the Sare Shisanwei Pengniao pills play a remarkable improvement role in model rat bone density, a bone biomechanics index, an HOP index in urine and a serum biochemical index and can be used for osteoporosis treatment, particularly treating osteoporosis resulting from estrogen lack.
Owner:SHANDONG JINHE DRUG RES DEV
A traditional Chinese medicine composition for treating rheumatoid arthritis inflammation and bone destruction and its application
InactiveCN105687397BSignificant inhibitory effect on toe swellingInhibition of toe swellingDispersion deliveryAntipyreticSide effectRhizome
The invention relates to traditional Chinese medicine composition for treating rheumatoid arthritis and bone destruction and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from raw materials in parts by weight as follows: 10-20 parts of Japan sabia, 15-30 parts of malaytea scurfpea fruits, 15-30 parts of fortune's drynaria rhizomes, 9-15 parts of Chinese angelica and 15-20 parts of epimedium herbs. The traditional Chinese medicine composition has a remarkable inhibition function on toe swelling of a rheumatoid arthritis animal model, can remarkably reduce loss of bone mass around an inflammable joint of the rheumatoid arthritis animal model, improves the bone biomechanical parameter and inhibits bone destruction caused by rheumatoid arthritis; the traditional Chinese medicine composition has the advantages that a few raw materials are required, preparation is convenient, the cost is low, and no toxic and side effects are caused.
Owner:肖涟波 +2
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