6 results about "Bone biomechanics" patented technology

The application discloses a bone health tablet candy rich in marine peptide calcium chelate and a preparation method thereof, and belongs to the technical field of polypeptides, wherein the calcium chelate peptide provided by the application has an amino acid sequence as shown in SEQ ID No.1, and the specific sequence is GETGPA (F21-1), and the calcium binding capacity of the calcium chelate peptide is 4.72±1.06 μg / mg. The bone health tablet candy provided by the application has good calcium absorption promoting activity. The results of a mouse experiment show that the bone health tablet candy does not cause adverse effects on the growth of mice, can reverse high bone conversion caused by osteoporosis, improves the bone biomechanical properties of osteoporotic mice, and thus achieves the effect of enhancing bone density.

The present invention discloses a preparation method and application of fermented milk rich in osteogenic growth peptide FPPQSVL, and belongs to the technical field of dairy product processing. The present invention prepares Lactobacillus helveticus fermented milk rich in osteogenic growth peptide FPPQSVL by inoculating Lactobacillus helveticus CCFM1263 into skimmed milk for fermentation. The fermented milk has the functions of significantly enhancing bone density, significantly increasing the number and thickness of trabeculae, significantly increasing bone volume fraction, significantly enhancing the bone biomechanics of rats, and significantly reducing the content of bone turnover biomarkers TRAP, CTX-1, and DPD in serum, while significantly increasing the content of BALP. The Lactobacillus helveticus fermented milk rich in osteogenic growth peptide FPPQSVL provided by the present invention can effectively prevent or treat osteoporosis, promote bone health, and is of great significance to the development of health products and medicines that promote bone health.

The application discloses application of black corn polysaccharide in preparation of a medicine for preventing or treating senile osteoporosis. The evaluation of the prevention or treatment effect of the black corn polysaccharide on senile osteoporosis includes improvement effects on serum bone metabolism markers, bone microstructure and bone biomechanics. The black corn polysaccharide of the application refers to a polysaccharide powder after water extraction, alcohol precipitation, Sevag method deproteinization, H2O2 method depigmentation and dialysis bag dialysis from dried black corn kernels. The black corn polysaccharide has improvement effects on imbalance of serum bone metabolism markers of senile osteoporosis, deterioration of bone microstructure and decrease of bone strength. The results show that the black corn polysaccharide has great improvement effects on bone loss in preventing senile osteoporosis. Therefore, the black corn polysaccharide has important significance in developing senile osteoporosis in clinic.

The application discloses application of a lignan and flaxseed polysaccharide in preparation of health care products for improving osteoporosis, and belongs to the technical field of health care functions. The postmenopausal osteoporosis model is established by ovariectomized rats, and the comparison of the lignan and flaxseed polysaccharide on bone metabolism, related bone conversion indexes, bone microstructure, bone biomechanics and intestinal flora of the rats is systematically studied, so that the dominant material for improving osteoporosis of the lignan and flaxseed polysaccharide is explored, and a more effective theoretical basis is provided for development of functional food of flaxseed.

The present application provides a Chlorella pyrenoidosa calcium-chelating peptide and a Chlorella pyrenoidosa peptide calcium-chelate prepared by using the Chlorella pyrenoidosa calcium-chelating peptide; the prepared Chlorella pyrenoidosa peptide calcium-chelate can enhance the maximum load and structural strength of the tibia of an osteoporosis mouse. The Chlorella pyrenoidosa calcium-chelating peptide provided by the present application combines with calcium ions to form a peptide calcium-chelate, and experiments on animals prove that the peptide calcium-chelate can significantly improve the maximum load and structural strength of the tibia of an osteoporosis mouse, and has a good effect of improving the bone biomechanical properties of an osteoporosis mouse.

The invention provides a traditional Chinese medicine composition for preventing or treating osteoporosis. The colla corii asini polypeptide composition is prepared from colla corii asini polypeptide, cornu cervi pantotrichum, eurycoma longifolia, mulberries and dried blood oranges according to a specific proportion, through the synergistic effect of multiple traditional Chinese medicines, the bone mineral density, bone microstructure and bone biomechanical properties are remarkably improved, and the colla corii asini polypeptide composition is suitable for preventing or treating osteoporosis of middle-aged and elderly people.