Composition for increasing bone mineral density and preparation method of composition

A technology for increasing bone density and composition, applied in the field of bone density increasing composition and its preparation, can solve the problems of low extraction rate of active ingredients, unsatisfactory bone density curative effect, incomplete synergistic effect, etc., and achieve rich grid structure , improve growth and reproductive capacity, and improve the effect of intestinal micro-ecological environment

Inactive Publication Date: 2015-04-08
邵素英
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

[0009] The curative effect of the above-mentioned disclosed products for increasing bone density is far from satisfactory, and has the following defects: 1) the Chinese herbal medicine extract used has a simple formula and incomplete synergistic effect; 2) the Chinese herbal medicine extract is prepared by a traditional method, and the extraction rate of active ingredients 3) The calcium source disclosed in the product is mainly inorganic calcium or organic calcium such as calcium carbonate, which are all extracted, separated or synthesized by chemical methods. prepared, there are certain food safety hazards, the application of calcium carbonate will have side eff...

Method used

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  • Composition for increasing bone mineral density and preparation method of composition
  • Composition for increasing bone mineral density and preparation method of composition
  • Composition for increasing bone mineral density and preparation method of composition

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Embodiment 1

[0058] Embodiment 1 Raw material preparation

[0059] 1. Preparation of herbal extracts

[0060] The preparation method of the Chinese herbal medicine extract comprises the following steps: in parts by weight, weigh 20 parts of Eucommia ulmoides, 15 parts of Pueraria lobata, 11 parts of salvia miltiorrhiza, 10 parts of epimedium, 8 parts of drynaria, 5 parts of wolfberry, 4 parts of angelica Parts; put in an ultrasonic cleaning machine filled with 0.2% sodium bicarbonate solution, wash at 200W, 30KHz for 12min, drain, grind the above-mentioned Chinese herbal medicine to a particle size below 2 mm, put it in a container and mix evenly and add 5 times the weight of water , to obtain the mixed material, control the temperature at 80°C for 3 hours, then lower the temperature to 45°C, adjust the pH value to 4 with lactic acid, and carry out microwave extraction under the conditions of power 200W and frequency 2000Hz, wherein the total time of each microwave irradiation is 70s. Int...

Embodiment 2

[0069] A capsule for increasing bone density, mainly prepared from the following raw materials in parts by weight:

[0070] Glucosamine hydrochloride 23 parts, Chinese herbal medicine extract 20 parts, calcium carbonate 19 parts, calcium fruit extract 20 parts, chondroitin sulfate 8 parts, milk calcium 7 parts, casein calcium peptide 5 parts, magnesium lactate 4.8 parts, two 3 parts of methyl sulfone, 2.8 parts of grape seed extract, 0.21 parts of zinc lactate;

[0071] The capsule for increasing bone density also includes the following adjuvants in parts by weight:

[0072] 14 parts of maltodextrin, 11 parts of D-mannitol, 17 parts of modified dietary fiber, 1 part of hydroxypropyl methylcellulose, 1 part of citric acid, and 0.6 part of magnesium stearate.

[0073] The preparation method comprises the following steps:

[0074] 1) According to the formula, take glucosamine hydrochloride, Chinese herbal medicine extract, calcium carbonate, calcium fruit extract, chondroitin s...

Embodiment 3

[0079] A capsule for increasing bone density, mainly prepared from the following raw materials in parts by weight:

[0080] 15 parts of glucosamine hydrochloride, 12 parts of Chinese herbal medicine extract, 10 parts of calcium carbonate, 15 parts of calcium fruit extract, 5 parts of chondroitin sulfate, 2 parts of milk calcium, 2.5 parts of casein calcium peptide, 3 parts of magnesium lactate, two 2 parts of methyl sulfone, 1.5 parts of grape seed extract, 0.15 parts of zinc lactate;

[0081] The capsule for increasing bone density also includes the following adjuvants in parts by weight:

[0082] 5 parts of maltodextrin, 5 parts of D-mannitol, 5 parts of modified dietary fiber, 0.5 part of hydroxypropyl methylcellulose, 0.5 part of citric acid, 0.3 part of magnesium stearate;

[0083] The preparation method comprises the following steps:

[0084] 1) According to the formula, take glucosamine hydrochloride, Chinese herbal medicine extract, calcium carbonate, calcium fruit e...

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Abstract

The invention discloses a composition for increasing bone mineral density and a preparation method of the composition. Chinese dwarf cherry, a Chinese herbal medicine extract refined by a modern extraction technology and other raw materials with the function of increasing the bone mineral density are scientifically compounded, are scientifically combined in an omnibearing manner, and work together, so as to achieve the effects of effectively promoting absorption of calcium from a plurality of aspects, restoring and rebuilding cartilago articularis, creating synovial fluid, and promoting collagen synthesis in the cartilago articularis, preventing cartilage from further degenerating, indirectly reducing osteoclast action, inhibiting re-absorption of bones, increasing bone calcium content and improving the mechanical property of the bone, so that the product has a good effect of increasing the bone mineral density. The integrating property and the biological stability of the composition can be further improved by a microwave drying technology in the preparation method. Due to the oxidation resistance of a grape pip extract in the raw materials, high adsorption and embedding effects of modified dietary fiber, and antifungal properties of the Chinese herbal medicine extract, the efficient, safe, nutrient and stable composition with the function of increasing the bone mineral density is finally prepared.

Description

technical field [0001] The invention relates to a composition, in particular to a composition for increasing bone density and a preparation method thereof. Background technique [0002] In recent years, osteoporosis has become a disease that seriously threatens human health worldwide, and has attracted increasing attention. At present, there are more than 200 million osteoporosis patients in the world, and its incidence rate has jumped to the seventh among various common diseases in the world. It is generally believed that in the West, 1 in 4 women or 1 in 8 men suffers from this disease. In the United States, there are 10 million people with osteoporosis and 18 million people with low bone mass who may develop osteoporosis. There are 9-10 million elderly people suffering from osteoporosis in Japan, accounting for about 9% of the total population of Japan. It is estimated to affect approximately 75 million people in the United States, Europe, and Japan, the vast majority ...

Claims

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Application Information

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IPC IPC(8): A23L1/304A23L1/305A61K38/17A61K36/815A61P19/08A61P19/10A61K31/737A23L33/105A23L33/16A23L33/18
CPCA23V2002/00A23V2200/306A23V2250/21A23V2250/55A23V2250/161A23V2250/1642A23V2250/5114A23V2250/032
Inventor 邵素英
Owner 邵素英
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